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Our top choices for Santa Cruz hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (347)
"Great spacious property with nice pool!"
United States
Douglas
The price is AEDĀ 476
AEDĀ 476 total
4 Jan - 5 January 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is AEDĀ 408
AEDĀ 408 total
2 Jan - 3 January 2026
Marriott Santa Cruz de la Sierra Hotel

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (77)
"Great Spot"
United States
Jose
The price is AEDĀ 143
AEDĀ 143 total
25 Dec - 26 Dec
Ibis Santa Cruz DE LA Sierra

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.4 out of 10, Very Good, (331)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is AEDĀ 329
AEDĀ 329 total
26 Dec - 27 Dec
Sun Hotel

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (407)
"The parrots. Unique"
United States
Juan P
The price is AEDĀ 661
AEDĀ 661 total
25 Dec - 26 Dec
Camino Real Hotel

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (124)
"The staff and property are second to none! "
United States
Cynthia
The price is AEDĀ 448
AEDĀ 448 total
9 Jan - 10 January 2026
Hotel Cortez

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (104)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is AEDĀ 367
AEDĀ 367 total
8 Jan - 9 January 2026
Novotel Santa Cruz De La Sierra

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (36)
"Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!"
United States
Robert
HOTEL OSHO

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (256)
"Nice hotel "
United States
Narciso Lorenzo
The price is AEDĀ 338
AEDĀ 338 total
26 Dec - 27 Dec
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (93)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz

ChairĆŗ Eco Hotel

ChairĆŗ Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (48)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
ChairĆŗ Eco Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (81)
"Good price, great hotel!"
United States
James
The price is AEDĀ 143
AEDĀ 143 total
25 Dec - 26 Dec
Premium Suites Deluxe Aparthotel Equipetrol

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (145)
"Nice stay with good service "
United States
Jianyuan
The price is AEDĀ 327
AEDĀ 327 total
25 Dec - 26 Dec
TRYP by Wyndham Santa Cruz

SwissƓtel Santa Cruz De La Sierra

SwissƓtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (81)
"Beautiful hotel"
Australia
Joanna
The price is AEDĀ 544
AEDĀ 544 total
7 Jan - 8 January 2026
SwissƓtel Santa Cruz De La Sierra

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (73)
"Excellent place to stay!"
United States
Luisa
The price is AEDĀ 179
AEDĀ 179 total
29 Dec - 30 Dec
Delfines Collection Hotel By Mercure

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (30)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is AEDĀ 130
AEDĀ 130 total
1 Jan - 2 January 2026
Lido Hotel

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (40)
"Love it. Will stay again!!"
United States
Juan
The price is AEDĀ 389
AEDĀ 389 total
1 Jan - 2 January 2026
Alfonsina Hotel Boutique by Inboccaluppo

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (281)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (201)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol

Hotel Las AmƩricas

Hotel Las AmƩricas
3.0 star property
Santa Cruz
6.0 out of 10, (1)
"O chuveiro foi impossĆ­vel tomar um.banho de qualidade "
Brazil
Jean
The price is AEDĀ 141
AEDĀ 141 total
25 Dec - 26 Dec
Hotel Las AmƩricas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals inĀ Santa Cruz

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Top Santa Cruz Hotel Reviews

Guide to exploring around Santa Cruz

Top reasons to visit Santa Cruz

  • Bustling Local Markets: Experience the vibrant atmosphere of Santa Cruz's markets, where you can find local crafts, fresh produce, and delicious street food.
  • Vibrant Cultural Scene: Enjoy a mix of cultural events, including soccer matches and operas, showcasing the city's lively spirit.
  • Stunning Natural Parks: Explore national parks that offer breathtaking views and opportunities for outdoor adventures.
  • Friendly Locals: Engage with the warm and welcoming locals who enhance your travel experience with their hospitality.
  • Diverse Accommodations: Choose from a range of lodging options, including family-friendly hotels and cozy hostels.

Find great hotels in Santa Cruz

Discover a variety of accommodation options in Santa Cruz, Bolivia, ranging from family-friendly hotels to cozy hostels perfect for backpackers. Whether you're traveling for business or leisure, you'll find pet-friendly hotels and top-notch amenities to suit your needs. Experience the vibrant culture of Santa Cruz while enjoying comfortable stays at well-rated hotels. Explore your options and make your visit memorable in this beautiful city.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Nestled in the heart of Santa Cruz, Los Tajibos is a charming 3.5-star hotel that embodies a city-themed experience ideal for business travelers and families alike. This property prioritizes comfort and convenience, featuring amenities that cater to children, including a First Aid Kit for peace of mind. Its central location allows guests to easily explore the vibrant culture and attractions of Santa Cruz while enjoying the warm hospitality and well-appointed accommodations.
  • Hotel G: A unique 3.5-star lodging, Hotel G extends a warm welcome to pet lovers, making it an ideal choice for travelers with furry companions. This pet-friendly hotel permits dogs and cats, ensuring that no family member is left behind. With its thoughtful pet policy that waives fees for service animals and provides a comfortable environment for pets, Hotel G combines a relaxed atmosphere with modern amenities, making it a great choice for those looking to spend quality time with their pets while enjoying the local scenery.
  • Marriott Santa Cruz de la Sierra Hotel: Experience luxury at its finest at the 5-star Marriott Santa Cruz de la Sierra Hotel, where every detail is designed for relaxation and indulgence. Perfect for business travelers and spa enthusiasts, this hotel features an extensive onsite spa offering a range of treatments, an outdoor pool, and accessible facilities to ensure a rejuvenating stay. Guests can unwind in elegant accommodations while enjoying top-notch service, making it an excellent choice for those seeking a high-end escape in Santa Cruz.

Where to stay in Santa Cruz

Santa Cruz, Bolivia, is a vibrant destination perfect for city lovers and families alike. Experience stunning city views and stylish getaways in this tropical paradise. Explore the bustling local markets, relax on beautiful beaches, and enjoy friendly interactions with the locals. With its mix of exciting excursions and laid-back atmospheres, Santa Cruz offers an unforgettable vacation for travelers seeking both adventure and relaxation in a great location.

  • Santa Cruz: Santa Cruz is a vibrant city known for its cultural richness and urban charm. Nestled in the heart of Bolivia, it attracts visitors year-round, with peak tourist seasons occurring in January, July, and September. Travelers flock here for a city-themed experience, where shopping malls and cinema offer entertainment, while local landmarks such as the piazza square and cathedral provide a glimpse into the city’s historical and spiritual significance. Enjoy the lively atmosphere and diverse culinary offerings as you explore this dynamic urban center.
  • Samaipata: Located a short drive from Santa Cruz, Samaipata is a charming city that offers breathtaking outdoor adventures and stunning scenery. With peak visitor numbers in January, July, and September, this area is perfect for those seeking a blend of nature and culture. Popular activities include hiking on scenic trails and exploring vibrant local markets. Notable attractions include archaeological sites and museums that highlight the region's rich history, making it an ideal destination for adventure seekers and history buffs alike.
  • Warnes: Warnes is a family-friendly city that combines urban experiences with outdoor activities. Situated close to Santa Cruz, it sees a rise in visitors during September and from December to January. The city features resorts and shopping centers, making it a convenient getaway for families. The botanical garden is a must-visit, offering a serene environment to relax and appreciate nature. Warnes provides a perfect blend of city life and outdoor exploration, ensuring a delightful experience for all ages.

Things to do in Santa Cruz

Santa Cruz offers a vibrant mix of activities perfect for city-themed, family, and sports vacations. Visitors can explore bustling markets, catch an exciting soccer match, or enjoy a night at the opera, making it an ideal destination for diverse interests and unforgettable experiences.

Shopping

Ventura Mall offers a vibrant shopping experience with entertainment and family-friendly vibes. For unique gifts, visit La Recova Artisan Walk, where local artisans showcase their crafts. Lastly, Patio Design LifeStyle Center combines shopping with a relaxed atmosphere perfect for families and business enthusiasts alike.

Recreation

Ramon Tahuichi Aguilera Stadium is a vibrant sports facility in Santa Cruz, offering an energetic atmosphere ideal for fitness enthusiasts. Engage in recreational activities or attend exciting sporting events while soaking in the local culture and community spirit.

Adventure

Experience the thrills of the Lomas de Arena Regional Park, where you can sandboard down stunning dunes and explore the unique desert landscape. For a dose of adrenaline, try zip-lining at Parque Aventura, soaring above lush greenery and enjoying breathtaking views of the surrounding area.

Nightlife

Experience the vibrant nightlife in Santa Cruz with a visit to Cine Center, where you can catch the latest films in a romantic and family-friendly atmosphere. For a taste of culture, head to Casa Municipal de Cultura RaĆŗl Otero Reiche, a theater that offers enchanting performances in a lively setting.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money on your trip to Santa Cruz, Bolivia, consider visiting during the cheaper months of January, June, or August. Saturdays offer the lowest accommodation rates, while Tuesdays tend to be the priciest. Use Expedia’s search tool to find budget-friendly hotel options, and don't forget to apply the price filter for the best deals. Combining your hotel stay with flights and activities can lead to great package savings. For transportation, walking is a cost-effective way to explore the city, allowing you to enjoy various free activities along the way.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are January, June and August, where the prices are slightly lower. This is in comparison to March, September and December, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to customize your options based on your budget, desired location, and preferred type of accommodation. To find the best prices and offers, arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Santa Cruz with your flights and activities through an Expedia package deal.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is perfect for city-themed, family, and sports vacations, offering a mix of cultural and outdoor adventures. Explore popular attractions like national parks, cathedrals, and local landmarks that showcase the vibrant culture and scenic beauty of the area. Whether you're seeking excitement or a leisurely experience, Santa Cruz has something for every traveler to enjoy.

  • Plaza 24 de Septiembre: Experience the vibrant heart of Santa Cruz at this bustling square, surrounded by charming cafes and colonial architecture. It's a perfect spot to immerse yourself in local culture and enjoy people-watching amidst the lively atmosphere.
  • Amboró National Park: Discover the breathtaking beauty of nature at Amboró National Park, where lush forests and diverse wildlife await. Perfect for outdoor enthusiasts, the park offers hiking trails, stunning views, and a chance for adventure in a pristine environment.
  • San Lorenzo Cathedral: Visit this stunning example of colonial architecture, renowned for its beautiful interior and serene ambiance. The San Lorenzo Cathedral is a cultural gem, offering insight into the religious heritage of the region and a peaceful retreat from the city’s hustle.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.700000000000003°C)Light RainMostly SunnySlightly LowSlightly Low
February77.0°F (25.0°C)Light RainMostly CloudySlightly HighAverage
March76.5°F (24.700000000000003°C)Light RainMostly SunnyAverageSlightly High
April74.5°F (23.6°C)Light RainMostly SunnyAverageAverage
May70.2°F (21.200000000000003°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnyAverageAverage
August72.9°F (22.700000000000003°C)No RainSunnySlightly HighSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnyAverageAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowSlightly High

The nearest major airports for your trip to Santa Cruz

When visiting Santa Cruz, Bolivia, the primary airport is Viru Viru International Airport (VVI), located 16.1km from the city. Nearby, you'll find excellent accommodations such as the five-star Marriott Santa Cruz de la Sierra and Radisson Hotel Santa Cruz, both approximately 14.5km away. Another great option is the Novotel Santa Cruz De La Sierra, situated 17.7km from the airport. For travelers considering other airports, Monteagudo (MHW) and Potosi (POI) are located 150 and 331.5km away, respectively, with hotels like Coloso Potosi and Hotel Santa Monica providing transportation services to Potosi Airport.

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Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from AEDĀ 130 in a few different ways on Expedia. First, key in the dates you'd like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ĀŗC to 31ĀŗC. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from AEDĀ 130 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveler experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Book your Santa Cruz hotel with Expedia and enjoy a world of options at unbeatable prices. Use our search filters to help you find exactly what you want, whether that's a 5-star escape or something a little more unique, like a houseboat, log cabin or villa! Join Expedia Rewards and you'll save 10% or more on over 100,000 hotels worldwide when you're signed in. Collect points on eligible bookings, which you can use to save on your next epic adventure. Plus, many of our hotels come with flexible cancellation policies, so you can rest easy if your plans happen to change.