The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Shwetha

AED 450

AED 510 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A breakfast buffet with a bakery section, a coffee station, and a sign indicating the availability of breakfast.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

AED 419

AED 475 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

AED 230

AED 268 total

includes taxes & fees

1 Nov - 2 Nov

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

4. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

AED 465

AED 528 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with a circular fire pit surrounded by wicker chairs and a table.

A modern hotel lobby with a mix of seating areas, a bar, and a large wall-mounted TV.

A reception area with a large screen displaying a sea view, a bench, and a sign indicating the location as Marriott Bonvoy.

An indoor swimming pool with a 3 FT depth marker, a wheelchair-accessible chair, a potted plant, and a view of the outside through large windows.

5. SpringHill Suites by Marriott Durham Chapel Hill

12.6 km from Duke Regional Hospital

Logan

AED 470

AED 533 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A person performing a yoga pose outdoors with trees and a golf course in the background.

6. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Antonio

AED 882

AED 1,001 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

AED 434

AED 491 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with a table set for a meal, surrounded by chairs and a red umbrella.

A tented outdoor dining area with round tables set for a meal, each with white chairs and yellow tablecloths.

A tranquil lakeside setting with a dock, boats, and a seating area.

A bathroom with a granite countertop, a mirror, and a potted plant.

8. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Stephen

AED 378

AED 429 total

includes taxes & fees

5 Nov - 6 Nov

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

A multi-story hotel with a prominent "HOME 2" sign, a brick facade, and a well-lit entrance.

9. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

AED 528

AED 599 total

includes taxes & fees

25 Oct - 26 Oct

A swimming pool with lounge chairs and a wooden fence.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

10. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Jessica

AED 496

AED 563 total

includes taxes & fees

21 Oct - 22 Oct

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A hotel reception area with a counter, coffee station, and a large window with curtains.

A courtyard with a pathway leading to a building with large windows and a yellow facade.

A hotel lobby with a reception desk, a modern abstract sculpture, and a patterned floor.

11. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 10.4 km from Duke Regional Hospital

Yolanda

AED 311

AED 353 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with high ceilings, a central fountain, and seating areas.

A bar area with multiple liquor cabinets and hanging pendant lights.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

A spacious lobby with a curved seating area, large windows, and a modern chandelier.

12. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

18.2 km from Duke Regional Hospital

Darren C.

AED 584

AED 662 total

includes taxes & fees

25 Oct - 26 Oct

A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.

A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

A bar area with wooden shelves, a chalkboard menu, and various bottles.

A covered porch with steps leading to a door, a brick wall, and a street lamp.

13. The Colonial Inn, an Ascend Collection Hotel

18.6 km from Duke Regional Hospital

Elizabeth

AED 399

AED 452 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel reception area with two wooden reception desks, a large digital display wall, and a seating area with chairs.

A modern lobby with a fireplace, seating area, and wooden wall accents.

A modern restaurant with bar seating, a Starbucks sign, and a bar area with a counter and shelves.

14. Hilton Durham near Duke University

5.4 km from Duke Regional Hospital

tigist

AED 419

AED 475 total

includes taxes & fees

21 Oct - 22 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

15. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Alton

AED 404

AED 458 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

A bar area with a granite countertop, wooden chairs, and a large television screen.

16. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Michael

AED 481

AED 546 total

includes taxes & fees

9 Nov - 10 Nov

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

17. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.3 km from Duke Regional Hospital

BRIAN

AED 343

AED 389 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

A modern hotel lobby with seating areas, large windows, and a dining section.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

18. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

AED 512

AED 580 total

includes taxes & fees

18 Oct - 19 Oct

A long, narrow hallway with dark walls and wooden flooring.

A compact kitchenette with a refrigerator, microwave, and a flat-screen TV on a dark cabinet.

A modern reception area with a reception desk, a seating area with chairs and a table, and a bookshelf with books.

A hotel room with a large bed, two bedside lamps, a chair, a desk, a heater, and a window with curtains.

19. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Nicole

AED 443

AED 503 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a nightstand with a lamp, and a window with a view of trees.

A shelf stocked with various snack items, including boxed cereals and candy.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A gym with treadmills, elliptical machines, and exercise bikes.

20. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

16.9 km from Duke Regional Hospital

Sharon

AED 397

AED 467 total

includes taxes & fees

11 Nov - 12 Nov

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,006 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,005 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 573 reviews	View
SpringHill Suites by Marriott Durham Chapel Hill	9.2 Wonderful 1,002 reviews	View

Top Duke Regional Hospital Hotel Reviews

Hilton Durham near Duke University

10/10 Excellent

"Good location and has all ameneties for a comfortable stay"

Courtyard Durham Near Duke University/Downtown

10/10 Excellent

"I want to personally thank "HEIDI", the front desk staff person. She was fantatstic in every way. She went the extra mile to help us check in early and made sure we were accommodated. Please commend her."

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

The Lodge at Duke Medical Center

8/10 Good

"Very convenient to the medical center and university. The staff was very helpful. Good value. Very safe."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

21c Museum Hotel Durham

10/10 Excellent

"Stellar customer service!! Look elsewhere for food."

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from AED 268

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Hampton Inn & Suites Durham University Medical Center

5. SpringHill Suites by Marriott Durham Chapel Hill

6. Washington Duke Inn & Golf Club

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

8. DoubleTree Suites by Hilton Raleigh - Durham

9. Home2 Suites by Hilton Durham University Medical Center

10. Hyatt Place Durham Southpoint

11. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

12. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

13. The Colonial Inn, an Ascend Collection Hotel

14. Hilton Durham near Duke University

15. Hyatt House Raleigh / RDU / Brier Creek

16. Hilton Garden Inn Durham/University Medical Center

17. Comfort Inn & Suites Durham near Duke University

18. Residence Inn Raleigh-Durham Airport/Brier Creek

19. University Inn Durham next to Duke University Medical Center

20. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Hilton Durham near Duke University

Courtyard Durham Near Duke University/Downtown

Everything within 1 mile

The Lodge at Duke Medical Center

Unscripted Durham, Part of JDV by Hyatt

21c Museum Hotel Durham

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Cottage with Yard, Mins to Duke

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Frequently asked questions