The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Shwetha

AED 450

AED 510 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A gym with various exercise machines, a large mirror, and a television on the wall.

A breakfast buffet with a bakery section, a coffee station, and a sign indicating the availability of breakfast.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

AED 419

AED 475 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

AED 230

AED 268 total

includes taxes & fees

1 Nov - 2 Nov

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

4. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

AED 465

AED 528 total

includes taxes & fees

25 Oct - 26 Oct

A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.

A bar area with wooden shelves, a chalkboard menu, and various bottles.

A colonial-style building with a covered porch, multiple windows, and outdoor seating.

A covered porch with steps leading to a door, a brick wall, and a street lamp.

5. The Colonial Inn, an Ascend Collection Hotel

18.6 km from Duke Regional Hospital

Elizabeth

AED 399

AED 452 total

includes taxes & fees

25 Oct - 26 Oct

A modern indoor space with multiple seating areas, including tables and chairs, a television, and decorative shelves.

A multi-story hotel with a prominent "HOME 2" sign, a brick facade, and a well-lit entrance.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

6. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

AED 528

AED 599 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

7. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Chip

AED 436

AED 495 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

AED 434

AED 491 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern living room with a fireplace, seating area, and a pool table.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

9. JB Duke Hotel

6.2 km from Duke Regional Hospital

samantha

AED 731

AED 830 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

A bar area with multiple liquor cabinets and hanging pendant lights.

A spacious lobby with a curved seating area, large windows, and a modern chandelier.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

10. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

18.2 km from Duke Regional Hospital

Darren C.

AED 584

AED 662 total

includes taxes & fees

25 Oct - 26 Oct

A bar area with multiple shelves of bottles, glasses, and a bar counter.

An outdoor dining area with tables and chairs, large windows, and a view of greenery.

A modern living room with a pool table, a sofa, and a dining area.

11. The Westin Raleigh-Durham Airport

18.2 km from Duke Regional Hospital

Dina

AED 790

AED 894 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

12. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Sharon

AED 491

AED 556 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

13. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Lowell

AED 882

AED 1,001 total

includes taxes & fees

25 Oct - 26 Oct

A swimming pool with lounge chairs and a wooden fence.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

A spacious lobby with a reception desk, seating area, and artwork on the walls.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

14. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Jessica

AED 496

AED 563 total

includes taxes & fees

21 Oct - 22 Oct

An outdoor patio with a table set for a meal, surrounded by chairs and a red umbrella.

A tented outdoor dining area with round tables set for a meal, each with white chairs and yellow tablecloths.

A tranquil lakeside setting with a dock, boats, and a seating area.

A hotel room with two beds, a desk, a mirror, a television, and a kitchenette.

15. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Stephen

AED 378

AED 429 total

includes taxes & fees

5 Nov - 6 Nov

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

16. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

AED 404

AED 458 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with wicker furniture and a stone fire pit.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

A conference room with a long table, chairs, and a modern chandelier.

17. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

AED 512

AED 580 total

includes taxes & fees

18 Oct - 19 Oct

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

A bar area with a granite countertop, wooden chairs, and a large television screen.

18. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Michael

AED 481

AED 546 total

includes taxes & fees

9 Nov - 10 Nov

A spacious, elegantly decorated interior with a central round table, high ceilings, and classic architectural columns.

A spacious living room with a sofa, armchairs, a coffee table, and a chandelier.

A large, historic building with a central courtyard, columns, and a brick facade.

A well-lit living room with a sofa, armchairs, a coffee table, and a fireplace.

19. The Carolina Inn, a Destination by Hyatt Hotel

19.9 km from Duke Regional Hospital

Stephanie Pauline

AED 1,370

AED 1,555 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.

A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.

A modern dining area with wooden tables and chairs, large windows, and geometric pendant lighting.

A modern hotel lobby with a reception desk, a beverage refrigerator, and a well-stocked snack bar.

20. SpringHill Suites by Marriott Durham City View

5.4 km from Duke Regional Hospital

Taurean

AED 471

AED 535 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,006 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,005 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 574 reviews	View
The Colonial Inn, an Ascend Collection Hotel	9.6 Exceptional 323 reviews	View

Top Duke Regional Hospital Hotel Reviews

Courtyard Durham Near Duke University/Downtown

10/10 Excellent

"Everyone was nice; the room was super clean!"

Comfort Inn & Suites Durham near Duke University

8/10 Good

"The property is well located, easily accessed from I-85. Breakfast was ok. Bathroom very modern. My only complaint is that I saw two small cockroaches in the room, about half an inch, one near the bathroom (I think I killed it), the other one near the window."

Hilton Durham near Duke University

10/10 Excellent

"Good location and has all ameneties for a comfortable stay"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

The Lodge at Duke Medical Center

8/10 Good

"Very convenient to the medical center and university. The staff was very helpful. Good value. Very safe."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from AED 268

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Hampton Inn & Suites Durham University Medical Center

5. The Colonial Inn, an Ascend Collection Hotel

6. Home2 Suites by Hilton Durham University Medical Center

7. Fairfield by Marriott Inn & Suites Durham

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

9. JB Duke Hotel

10. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

11. The Westin Raleigh-Durham Airport

12. Courtyard Raleigh-Durham Airport/Brier Creek

13. Washington Duke Inn & Golf Club

14. Hyatt Place Durham Southpoint

15. DoubleTree Suites by Hilton Raleigh - Durham

16. Hyatt House Raleigh / RDU / Brier Creek

17. Residence Inn Raleigh-Durham Airport/Brier Creek

18. Hilton Garden Inn Durham/University Medical Center

19. The Carolina Inn, a Destination by Hyatt Hotel

20. SpringHill Suites by Marriott Durham City View

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Courtyard Durham Near Duke University/Downtown

Comfort Inn & Suites Durham near Duke University

Hilton Durham near Duke University

Everything within 1 mile

The Lodge at Duke Medical Center

Unscripted Durham, Part of JDV by Hyatt

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Cottage with Yard, Mins to Duke

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Frequently asked questions