The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Shwetha

AED 450

AED 510 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A swimming pool with a metal railing, surrounded by a building with multiple windows and a sign indicating no lifeguard on duty.

A hotel lobby with a seating area, a reception desk, and artwork on the walls.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

AED 378

AED 429 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

AED 230

AED 268 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

4. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Chip

AED 436

AED 495 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

5. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

AED 434

AED 491 total

includes taxes & fees

25 Oct - 26 Oct

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

6. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

AED 465

AED 528 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

7. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Shelby

AED 404

AED 458 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

8. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

AED 491

AED 556 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

An outdoor patio area with wicker furniture, stone pillars, and string lights.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

A bar area with multiple liquor cabinets and hanging pendant lights.

9. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

18.2 km from Duke Regional Hospital

Darren C.

AED 584

AED 662 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

A modern hotel lobby with seating areas, large windows, and a dining section.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

10. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

AED 512

AED 580 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio with a table set for a meal, surrounded by chairs and a red umbrella.

A tented outdoor dining area with round tables set for a meal, each with white chairs and yellow tablecloths.

A bathroom with a granite countertop, a mirror, and a potted plant.

A hotel room with a large bed, two bedside tables, and two wall-mounted lamps.

11. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Sierra

AED 378

AED 429 total

includes taxes & fees

5 Nov - 6 Nov

12. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

AED 528

AED 599 total

includes taxes & fees

25 Oct - 26 Oct

A long, narrow hallway with dark walls and wooden flooring.

A compact kitchenette with a refrigerator, microwave, and a flat-screen TV on a dark cabinet.

A hotel room with a large bed, two bedside lamps, a chair, a desk, a heater, and a window with curtains.

A modern reception area with a reception desk, a seating area with chairs and a table, and a bookshelf with books.

13. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Nicole

AED 380

AED 431 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern living room with a fireplace, seating area, and a pool table.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

14. JB Duke Hotel

6.2 km from Duke Regional Hospital

samantha

AED 607

AED 689 total

includes taxes & fees

12 Nov - 13 Nov

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A person performing a yoga pose outdoors with trees and a golf course in the background.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

15. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Lowell

AED 882

AED 1,001 total

includes taxes & fees

26 Oct - 27 Oct

A modern living room with a pool table, a sofa, and a dining area.

A bar area with multiple shelves of bottles, glasses, and a bar counter.

A modern restaurant with long communal tables, hanging pendant lights, and geometric patterned walls.

16. The Westin Raleigh-Durham Airport

18.2 km from Duke Regional Hospital

Dina

AED 790

AED 894 total

includes taxes & fees

1 Nov - 2 Nov

A swimming pool with lounge chairs and a wooden fence.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

A spacious lobby with a reception desk, seating area, and artwork on the walls.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

17. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Jessica

AED 496

AED 563 total

includes taxes & fees

22 Oct - 23 Oct

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

A bar area with a granite countertop, wooden chairs, and a large television screen.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

18. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Michael

AED 481

AED 546 total

includes taxes & fees

9 Nov - 10 Nov

A hotel room with two beds, a nightstand with a lamp, and a window with a view of trees.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A shelf stocked with various snack items, including boxed cereals and candy.

An outdoor seating area with tables and chairs, a paved walkway, and a fence.

19. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

16.9 km from Duke Regional Hospital

Nathaniel

AED 353

AED 417 total

includes taxes & fees

16 Nov - 17 Nov

A spacious lobby with a reception desk, a central seating area with a round table and chairs, and a staircase leading to an upper level.

A modern interior with a kitchen area, dining space, and seating.

A covered outdoor area with a symmetrical design, featuring a central seating area with chairs and a table, flanked by columns and potted plants.

20. Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle

17.3 km from Duke Regional Hospital

Andrew

AED 418

AED 475 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,000 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,000 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
Fairfield by Marriott Inn & Suites Durham	9.6 Exceptional 60 reviews	View
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek	9.4 Exceptional 1,001 reviews	View

Top Duke Regional Hospital Hotel Reviews

Comfort Inn & Suites Durham near Duke University

10/10 Excellent

"Breakfast was great!!!"

Hilton Durham near Duke University

10/10 Excellent

"Good location and has all ameneties for a comfortable stay"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

The Lodge at Duke Medical Center

8/10 Good

"Very convenient to the medical center and university. The staff was very helpful. Good value. Very safe."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

10/10 Excellent

"We loved it! Rooms were large and well decorated, everything was so cute! We played football in the yard and lots of other games. The neighborhood is really nice and safe too. Lots of kids and families. I would definitely stay again!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from AED 268

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Fairfield by Marriott Inn & Suites Durham

5. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

6. Hampton Inn & Suites Durham University Medical Center

7. Hyatt House Raleigh / RDU / Brier Creek

8. Courtyard Raleigh-Durham Airport/Brier Creek

9. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

10. Residence Inn Raleigh-Durham Airport/Brier Creek

11. DoubleTree Suites by Hilton Raleigh - Durham

12. Home2 Suites by Hilton Durham University Medical Center

13. University Inn Durham next to Duke University Medical Center

14. JB Duke Hotel

15. Washington Duke Inn & Golf Club

16. The Westin Raleigh-Durham Airport

17. Hyatt Place Durham Southpoint

18. Hilton Garden Inn Durham/University Medical Center

19. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

20. Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Comfort Inn & Suites Durham near Duke University

Hilton Durham near Duke University

Everything within 1 mile

The Lodge at Duke Medical Center

Unscripted Durham, Part of JDV by Hyatt

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Cottage with Yard, Mins to Duke

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

Frequently asked questions