The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Cindy

AED 434

AED 492 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A breakfast buffet with a bakery section, a coffee station, and a sign indicating the availability of breakfast.

A gym with various exercise machines, a large mirror, and a television on the wall.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

AED 404

AED 459 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

AED 230

AED 268 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio with a stone fire pit surrounded by wicker furniture and a large window overlooking the building.

A modern bar area with a curved counter, bar stools, a coffee machine, and a refrigerated display of beverages.

A modern hotel lobby with a central bar area, seating arrangements, and large windows offering views of the outdoors.

A swimming pool with lounge chairs and a building with balconies in the background.

4. Courtyard Durham Near Duke University/Downtown

Croasdaile Farm Master, 3.5 km from Duke Regional Hospital

Billy

AED 303

AED 343 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A hotel reception area with a counter, coffee station, and a large window with curtains.

A hotel lobby with a reception desk, a modern abstract sculpture, and a patterned floor.

A swimming pool with lounge chairs and a view of a building with large windows.

5. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 10.4 km from Duke Regional Hospital

Yolanda

AED 308

AED 350 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

6. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.3 km from Duke Regional Hospital

BRIAN

AED 313

AED 355 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel reception area with two wooden reception desks, a large digital display wall, and a seating area with chairs.

A modern restaurant with bar seating, a Starbucks sign, and a bar area with a counter and shelves.

A hotel room with two beds, a desk, and a chair.

7. Hilton Durham near Duke University

5.4 km from Duke Regional Hospital

Kenny

AED 419

AED 475 total

includes taxes & fees

11 Oct - 12 Oct

A dining area with wooden chairs and a table, a kitchen with a red wall and a clock, and a wall-mounted artwork of the U.S. map.

A kitchen area with waffle makers, a coffee machine, and a sign indicating breakfast time.

A hotel room with a bed, bedside tables, a chair, and a desk.

A large, red sign with 'EconoLodge' written on it, set against a backdrop of lush greenery and a clear blue sky.

8. Econo Lodge Research Triangle Park

14.3 km from Duke Regional Hospital

Stanley

AED 194

AED 220 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

9. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

AED 434

AED 491 total

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

10. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Ahmed

AED 404

AED 458 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a TV, a desk, and a mirror.

A covered walkway with red brick walls and a concrete floor, leading to a parking area with cars.

A room with a patterned carpet, a double door with a window, a vending machine, and a potted plant.

A reception area with a counter, a potted plant, a clock, and a red carpet.

11. OYO Hotel Durham West Hills

9.7 km from Duke Regional Hospital

Logan

AED 193

AED 215 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, bedside table, chair, desk, and a small kitchenette.

A hallway with vending machines and a refrigerator.

A compact kitchen with a microwave and a mini-fridge.

Two white washing machines in a room with tiled flooring.

12. Budget Inn

6 km from Duke Regional Hospital

Miguel Alfredo

AED 195

AED 221 total

includes taxes & fees

5 Oct - 6 Oct

A waterfall cascading over irregularly shaped rocks into a pond, surrounded by lush greenery and a building in the background.

A pool area with lounge chairs, a small building with a sign, and a mural of a beach scene.

A large stone building with multiple towers and windows, surrounded by a grassy area with trees.

A spacious lobby with a chandelier, a luggage stand, and a reception desk.

13. Millennium Hotel Durham

5.6 km from Duke Regional Hospital

Sinclair

AED 327

AED 371 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.

A modern kitchen with a microwave, coffee maker, and dishwasher. There is a round table with two green chairs in front.

A hotel room with a large bed, a bedside table with a lamp, a TV mounted on the wall, and a window with curtains.

A kitchen with a microwave, coffee maker, and a dishwasher.

14. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Stephen

AED 386

AED 438 total

includes taxes & fees

2 Nov - 3 Nov

A hotel with a prominent tower, a covered entrance, and a well-maintained garden.

A hotel room with two beds, a desk, a chair, a television, a window, and a bathroom with a sink and mirror.

A spacious lobby with a central seating area, a reception desk, and a skylight.

A swimming pool with a lifeguard stand and a metal railing, surrounded by a building with multiple windows and balconies.

15. La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint

14.4 km from Duke Regional Hospital

CHELSEA

AED 284

AED 323 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk, a TV, and a lamp.

A reception desk with a sign reading "Comfort Inn" and a clock above it.

A compact hotel room with a kitchenette, a sofa, a lamp, and a mirror.

A gym with exercise equipment, a TV, and a rack of dumbbells.

16. Comfort Inn University Durham - Chapel Hill

12.8 km from Duke Regional Hospital

Tracy

AED 312

AED 354 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with a circular fire pit surrounded by wicker chairs and a table.

A multi-story hotel with a flat facade, large windows, and a clear sky.

A reception area with a large screen displaying a sea view, a bench, and a sign indicating the location as Marriott Bonvoy.

A modern hotel lobby with a mix of seating areas, a bar, and a large wall-mounted TV.

17. SpringHill Suites by Marriott Durham Chapel Hill

12.6 km from Duke Regional Hospital

Logan

AED 470

AED 533 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

18. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

eidy

AED 492

AED 557 total

includes taxes & fees

18 Oct - 19 Oct

A modern building with a red roof and a sign that reads "Red Roof Inn."

A gazebo with picnic tables in a park with lush green grass and trees.

A hotel room with a vending machine, a water dispenser, and a washing machine.

A reception area with a stone wall, two red chairs, a reception desk, and a wall-mounted screen advertising a credit card offer.

19. Red Roof Inn Chapel Hill - UNC

13.3 km from Duke Regional Hospital

KANDI

AED 250

AED 289 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a covered entrance, a flagpole, and a parking area.

A hotel room with a large bed, a desk, a chair, a television, and a framed picture on the wall.

A compact kitchenette with a microwave, a small refrigerator, and a sink.

A hotel kitchen with a microwave, coffee machine, and juicer. There are wooden cabinets and a table with a plant.

20. Microtel Inn & Suites by Wyndham Hillsborough

18.6 km from Duke Regional Hospital

Fouad

AED 245

AED 278 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,000 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,002 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,002 reviews	View
Courtyard Durham Near Duke University/Downtown	8.2 Very good 1,000 reviews	View
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill	8.6 Excellent 1,987 reviews	View

Top Duke Regional Hospital Hotel Reviews

Comfort Inn & Suites Durham near Duke University

8/10 Good

"Unsure"

Holiday Inn Express Durham by IHG

8/10 Good

"Clean rooms"

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent

"Convenient"

University Inn Durham next to Duke University Medical Center

10/10 Excellent

"Very clean and large room. Convenient to Duke campus."

Millennium Hotel Durham

10/10 Excellent

"Good"

The Durham Hotel

10/10 Excellent

"One of the best hotels I have ever been to.. period world wide. Nice rooms, modern era decor, great in house restaurant with superb breakfast at reasonable price and coffee bar. Best cortado I ever had. All staff were friendly and super supportive. Parking in lots street or garage within easy walking distance. Many restaurants and bars in the area. Reasonably safe area but there are panhandlers on occasion. Room had adequate closet space, excellent bathroom and shower. Quiet at night. Super comfy bed. I’m a coffee nerd and they offer fresh ground gourmet options brought to your door each morning if you choose the night before. No hotel I’ve ever stayed at offered this. I liked it so much I returned on a return visit to the city. No pool but workout facility. Highly recommended if you travel in the area.,"

The Lodge at Duke Medical Center

10/10 Excellent

"My stay was great!"

Drexall Haven - Stylish + Peaceful Stay

8/10 Good

"The house is newly renovated so everything looks really nice. The only issue I have is a lack of dressers for our clothes. Otherwise the experience was great. Quiet neighborhood out of the way but accessible."

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"Kristin was a wonderful host and we loved our stay! The house was so thoughtfully curated and comfortable. We would definitely stay here again if we visit Durham in the future!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from AED 215

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Courtyard Durham Near Duke University/Downtown

5. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

6. Comfort Inn & Suites Durham near Duke University

7. Hilton Durham near Duke University

8. Econo Lodge Research Triangle Park

9. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

10. Hyatt House Raleigh / RDU / Brier Creek

11. OYO Hotel Durham West Hills

12. Budget Inn

13. Millennium Hotel Durham

14. DoubleTree Suites by Hilton Raleigh - Durham

15. La Quinta Inn & Suites by Wyndham Raleigh/Durham Southpoint

16. Comfort Inn University Durham - Chapel Hill

17. SpringHill Suites by Marriott Durham Chapel Hill

18. Courtyard Raleigh-Durham Airport/Brier Creek

19. Red Roof Inn Chapel Hill - UNC

20. Microtel Inn & Suites by Wyndham Hillsborough

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Comfort Inn & Suites Durham near Duke University

Holiday Inn Express Durham by IHG

Unscripted Durham, Part of JDV by Hyatt

University Inn Durham next to Duke University Medical Center

Millennium Hotel Durham

The Durham Hotel

The Lodge at Duke Medical Center

Drexall Haven - Stylish + Peaceful Stay

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Frequently asked questions