The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Shwetha

AED 450

AED 510 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A gym with various exercise machines, a large mirror, and a television on the wall.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

AED 419

AED 475 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

AED 230

AED 268 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A hotel reception area with a counter, coffee station, and a large window with curtains.

A swimming pool with lounge chairs and a view of a building with large windows.

A hotel lobby with a reception desk, a modern abstract sculpture, and a patterned floor.

4. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 10.4 km from Duke Regional Hospital

Yolanda

AED 311

AED 353 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

A modern living room with a fireplace, seating area, and a pool table.

A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

5. JB Duke Hotel

6.2 km from Duke Regional Hospital

samantha

AED 731

AED 830 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with a table set for a meal, surrounded by chairs and a red umbrella.

A hotel room with two beds, a desk, a mirror, a television, and a kitchenette.

A bathroom with a granite countertop, a mirror, and a potted plant.

A tented outdoor dining area with round tables set for a meal, each with white chairs and yellow tablecloths.

6. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Stephen

AED 378

AED 429 total

includes taxes & fees

5 Nov - 6 Nov

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

7. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

AED 465

AED 528 total

includes taxes & fees

25 Oct - 26 Oct

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

8. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Michael

AED 481

AED 546 total

includes taxes & fees

9 Nov - 10 Nov

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

9. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

AED 434

AED 491 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

An outdoor patio area with wicker furniture, stone pillars, and string lights.

A bar area with multiple liquor cabinets and hanging pendant lights.

10. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

18.2 km from Duke Regional Hospital

Darren C.

AED 584

AED 662 total

includes taxes & fees

25 Oct - 26 Oct

A long, narrow hallway with dark walls and wooden flooring.

A modern reception area with a reception desk, a seating area with chairs and a table, and a bookshelf with books.

A compact kitchenette with a refrigerator, microwave, and a flat-screen TV on a dark cabinet.

11. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Nicole

AED 426

AED 484 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

12. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Sharon

AED 491

AED 556 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel reception area with two wooden reception desks, a large digital display wall, and a seating area with chairs.

A modern restaurant with bar seating, a Starbucks sign, and a bar area with a counter and shelves.

A modern lobby with a fireplace, seating area, and wooden wall accents.

13. Hilton Durham near Duke University

5.4 km from Duke Regional Hospital

tigist

AED 419

AED 475 total

includes taxes & fees

21 Oct - 22 Oct

An outdoor seating area with a circular fire pit surrounded by wicker chairs and a table.

A reception area with a large screen displaying a sea view, a bench, and a sign indicating the location as Marriott Bonvoy.

A modern hotel lobby with a mix of seating areas, a bar, and a large wall-mounted TV.

A multi-story hotel with a flat facade, large windows, and a clear sky.

14. SpringHill Suites by Marriott Durham Chapel Hill

12.6 km from Duke Regional Hospital

Logan

AED 470

AED 533 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

A person performing a yoga pose outdoors with trees and a golf course in the background.

15. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Lowell

AED 882

AED 1,001 total

includes taxes & fees

25 Oct - 26 Oct

A swimming pool with lounge chairs and a wooden fence.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

16. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Jessica

AED 496

AED 563 total

includes taxes & fees

21 Oct - 22 Oct

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

17. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.3 km from Duke Regional Hospital

BRIAN

AED 343

AED 389 total

includes taxes & fees

25 Oct - 26 Oct

A modern indoor space with multiple seating areas, including tables and chairs, a television, and decorative shelves.

A multi-story hotel with a prominent "HOME 2" sign, a brick facade, and a well-lit entrance.

18. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

AED 528

AED 599 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

19. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Chip

AED 436

AED 495 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

20. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Alton

AED 404

AED 458 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,006 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,005 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill	8.6 Excellent 1,967 reviews	View
JB Duke Hotel	9.4 Exceptional 730 reviews	View

Top Duke Regional Hospital Hotel Reviews

Courtyard Durham Near Duke University/Downtown

10/10 Excellent

"Everyone was nice; the room was super clean!"

Comfort Inn & Suites Durham near Duke University

8/10 Good

"The property is well located, easily accessed from I-85. Breakfast was ok. Bathroom very modern. My only complaint is that I saw two small cockroaches in the room, about half an inch, one near the bathroom (I think I killed it), the other one near the window."

Hilton Durham near Duke University

10/10 Excellent

"Good location and has all ameneties for a comfortable stay"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

The Lodge at Duke Medical Center

8/10 Good

"Very convenient to the medical center and university. The staff was very helpful. Good value. Very safe."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from AED 268

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

5. JB Duke Hotel

6. DoubleTree Suites by Hilton Raleigh - Durham

7. Hampton Inn & Suites Durham University Medical Center

8. Hilton Garden Inn Durham/University Medical Center

9. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

10. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

11. University Inn Durham next to Duke University Medical Center

12. Courtyard Raleigh-Durham Airport/Brier Creek

13. Hilton Durham near Duke University

14. SpringHill Suites by Marriott Durham Chapel Hill

15. Washington Duke Inn & Golf Club

16. Hyatt Place Durham Southpoint

17. Comfort Inn & Suites Durham near Duke University

18. Home2 Suites by Hilton Durham University Medical Center

19. Fairfield by Marriott Inn & Suites Durham

20. Hyatt House Raleigh / RDU / Brier Creek

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Courtyard Durham Near Duke University/Downtown

Comfort Inn & Suites Durham near Duke University

Hilton Durham near Duke University

Everything within 1 mile

The Lodge at Duke Medical Center

Unscripted Durham, Part of JDV by Hyatt

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Cottage with Yard, Mins to Duke

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Frequently asked questions