The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Duke Regional Hospital hotels

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A gym with various exercise machines, a large mirror, and a television on the wall.

A workspace with two monitors, a printer, and a chair.

1. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

AED 404

AED 459 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

2. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

AED 230

AED 268 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A courtyard with a pathway leading to a building with large windows and a yellow facade.

A hotel reception area with a counter, coffee station, and a large window with curtains.

A swimming pool with lounge chairs and a view of a building with large windows.

3. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 10.4 km from Duke Regional Hospital

Barbara

AED 302

AED 343 total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor area with wooden flooring, multiple seating arrangements, and large windows offering a view of the outdoors.

A bathroom with a granite countertop, a mirror, and a potted plant.

A tented outdoor dining area with round tables set for a meal, each with white chairs and yellow tablecloths.

A hotel room with a large bed, two bedside tables, and two wall-mounted lamps.

4. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Sierra

AED 378

AED 429 total

includes taxes & fees

5 Nov - 6 Nov

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

5. JB Duke Hotel

6.2 km from Duke Regional Hospital

samantha

AED 731

AED 830 total

includes taxes & fees

25 Oct - 26 Oct

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

6. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

AED 503

AED 571 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

7. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Shelby

AED 404

AED 458 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

8. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Michael

AED 481

AED 546 total

includes taxes & fees

2 Nov - 3 Nov

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

9. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.3 km from Duke Regional Hospital

Robert

AED 335

AED 380 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

10. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Sharon

AED 475

AED 538 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a nightstand with a lamp, and a window with a view of trees.

A shelf stocked with various snack items, including boxed cereals and candy.

A gym with treadmills, elliptical machines, and exercise bikes.

A coffee station with two coffee machines and a variety of coffee pods and cups.

11. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

16.9 km from Duke Regional Hospital

Nathaniel

AED 437

AED 513 total

includes taxes & fees

1 Nov - 2 Nov

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A person performing a yoga pose outdoors with trees and a golf course in the background.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

12. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Lowell

AED 873

AED 991 total

includes taxes & fees

3 Nov - 4 Nov

An outdoor seating area with a circular fire pit surrounded by wicker chairs and a table.

A multi-story hotel with a flat facade, large windows, and a clear sky.

A reception area with a large screen displaying a sea view, a bench, and a sign indicating the location as Marriott Bonvoy.

A modern hotel lobby with a mix of seating areas, a bar, and a large wall-mounted TV.

13. SpringHill Suites by Marriott Durham Chapel Hill

12.6 km from Duke Regional Hospital

Logan

AED 470

AED 533 total

includes taxes & fees

25 Oct - 26 Oct

A long, narrow hallway with dark walls and wooden flooring.

A compact kitchenette with a refrigerator, microwave, and a flat-screen TV on a dark cabinet.

A hotel room with a large bed, two bedside lamps, a chair, a desk, a heater, and a window with curtains.

A modern reception area with a reception desk, a seating area with chairs and a table, and a bookshelf with books.

14. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Nicole

AED 426

AED 484 total

includes taxes & fees

30 Oct - 31 Oct

An outdoor patio with a stone fire pit surrounded by wicker furniture and a large window overlooking the building.

A modern hotel lobby with a central bar area, seating arrangements, and large windows offering views of the outdoors.

A modern living room with a fireplace, comfortable seating, and a large window offering a view of the outdoors.

A modern bar area with a curved counter, bar stools, a coffee machine, and a refrigerated display of beverages.

15. Courtyard Durham Near Duke University/Downtown

Croasdaile Farm Master, 3.5 km from Duke Regional Hospital

Billy

AED 340

AED 386 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with wooden ceiling beams, a central bar area, multiple seating options including sofas and chairs, and framed pictures on the walls.

A hotel room with two beds, a headboard, bedside lamps, a television, and a window with curtains.

A spacious indoor area with high ceilings, modern lighting fixtures, and a mix of seating arrangements including sofas and chairs.

A spacious lobby with a reception desk, comfortable seating, and a large window.

16. Hampton Inn & Suites Chapel Hill/Durham, Area

16 km from Duke Regional Hospital

Laura

AED 434

AED 493 total

includes taxes & fees

9 Nov - 10 Nov

A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.

A covered porch with steps leading to a door, a brick wall, and a street lamp.

A colonial-style building with a covered porch, multiple windows, and outdoor seating.

A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

17. The Colonial Inn, an Ascend Collection Hotel

18.6 km from Duke Regional Hospital

Matt W

AED 399

AED 452 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a reception desk, seating area, and a balcony.

A hotel dining area with tables, chairs, a decorative water feature, and a large window providing natural light.

A Wingate hotel with a beige facade, stone entrance, and an American flag.

A hotel room with a bed, a desk with a TV, a chair, and a lamp.

18. Wingate by Wyndham Raleigh Durham Airport RTP

18.2 km from Duke Regional Hospital

Supratik

AED 340

AED 386 total

includes taxes & fees

2 Nov - 3 Nov

An outdoor seating area with wicker furniture and a stone fire pit.

A modern hotel lobby with seating areas, large windows, and a dining section.

A conference room with a long table, chairs, and a modern chandelier.

19. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

AED 512

AED 580 total

includes taxes & fees

31 Oct - 1 Nov

A compact kitchen with a stainless steel refrigerator, a microwave, a coffee maker, and a dishwasher.

A modern hotel room with a desk, chair, and a television.

A modern kitchen with a long counter, various appliances, and a refrigerator.

A hotel room with a desk, chair, couch, and a small table with a lamp.

20. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

AED 528

AED 599 total

includes taxes & fees

29 Oct - 30 Oct

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Holiday Inn Express Durham by IHG	8.8 Excellent 1,000 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,001 reviews	View
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill	8.6 Excellent 1,981 reviews	View
DoubleTree Suites by Hilton Raleigh - Durham	9.2 Wonderful 1,000 reviews	View
JB Duke Hotel	9.4 Exceptional 737 reviews	View

Top Duke Regional Hospital Hotel Reviews

Hilton Durham near Duke University

10/10 Excellent

"Very friendly and accommodating staff! Clean rooms and great location."

Courtyard Durham Near Duke University/Downtown

10/10 Excellent

"Good, clean room, helpful staff, and very comfortable beds and room! Great location for visiting Duke hospital."

Millennium Hotel Durham

10/10 Excellent

"Nice place to stay"

Comfort Inn & Suites Durham near Duke University

8/10 Good

"The room we were given was very clean"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This is such a sweet cottage, so many details and there are instructions for EVERYTHING! NO guessing how to operate anything, they thought of it all,highly recommend to anyone! You can tell how much they care about every detail. I have stayed in many rentals and I can tell you this is a great deal for what you pay...very comfy beds, great linnens and the outdoor deck and front porch are a great bonus,plus there is a fireplace, but bring some starter kindling.Location is close to everything. Again, great value,it is really a little happy place,filled with little treasures!"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"Super cute and clean!"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from AED 268

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Duke Regional Hospital hotels

1. Holiday Inn Express Durham by IHG

2. Red Roof Inn Durham - Duke Univ Medical Center

3. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

4. DoubleTree Suites by Hilton Raleigh - Durham

5. JB Duke Hotel

6. Hampton Inn & Suites Durham University Medical Center

7. Hyatt House Raleigh / RDU / Brier Creek

8. Hilton Garden Inn Durham/University Medical Center

9. Comfort Inn & Suites Durham near Duke University

10. Courtyard Raleigh-Durham Airport/Brier Creek

11. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

12. Washington Duke Inn & Golf Club

13. SpringHill Suites by Marriott Durham Chapel Hill

14. University Inn Durham next to Duke University Medical Center

15. Courtyard Durham Near Duke University/Downtown

16. Hampton Inn & Suites Chapel Hill/Durham, Area

17. The Colonial Inn, an Ascend Collection Hotel

18. Wingate by Wyndham Raleigh Durham Airport RTP

19. Residence Inn Raleigh-Durham Airport/Brier Creek

20. Home2 Suites by Hilton Durham University Medical Center

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Hilton Durham near Duke University

Courtyard Durham Near Duke University/Downtown

Millennium Hotel Durham

Comfort Inn & Suites Durham near Duke University

Cottage with Yard, Mins to Duke

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Everything within 1 mile

Unscripted Durham, Part of JDV by Hyatt

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Frequently asked questions