The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

Shwetha

AED 450

AED 510 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A swimming pool with a metal railing, surrounded by a building with multiple windows and a sign indicating no lifeguard on duty.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Kimberly R

AED 404

AED 459 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Luis

AED 230

AED 268 total

includes taxes & fees

1 Nov - 2 Nov

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

4. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Nicole

AED 496

AED 563 total

includes taxes & fees

26 Oct - 27 Oct

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern living room with a fireplace, seating area, and a pool table.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

5. JB Duke Hotel

6.2 km from Duke Regional Hospital

samantha

AED 731

AED 830 total

includes taxes & fees

21 Oct - 22 Oct

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

A person performing a yoga pose outdoors with trees and a golf course in the background.

6. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Lowell

AED 872

AED 990 total

includes taxes & fees

21 Oct - 22 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Maurice

AED 434

AED 491 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

8. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Shelby

AED 404

AED 458 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

9. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Chip

AED 436

AED 495 total

includes taxes & fees

30 Oct - 31 Oct

A spacious indoor area with wooden flooring, multiple seating arrangements, and large windows offering a view of the outdoors.

A modern interior with wooden flooring, leather seating, and pendant lighting.

A bathroom with a granite countertop, a mirror, and a potted plant.

A hotel room with a large bed, two bedside tables, and two wall-mounted lamps.

10. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Sierra

AED 378

AED 429 total

includes taxes & fees

5 Nov - 6 Nov

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

A hotel room with a sofa, a small table, a desk, a chair, a TV, and a window with curtains.

11. Courtyard Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Sharon

AED 475

AED 538 total

includes taxes & fees

25 Oct - 26 Oct

A conference room with a long table, six chairs, a flat-screen TV, and a painting on the wall.

A row of electric vehicle charging stations with a sign indicating parking is only allowed while charging.

A swimming pool with a tiled deck, surrounded by lounge chairs and tables.

A hotel room with a bed, a desk, a chair, a television, and a bathroom visible through an open door.

12. Home2 Suites by Hilton Durham University Medical Center

5 km from Duke Regional Hospital

katey

AED 528

AED 599 total

includes taxes & fees

29 Oct - 30 Oct

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

A bar area with a granite countertop, wooden chairs, and a large television screen.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

13. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Michael

AED 481

AED 546 total

includes taxes & fees

9 Nov - 10 Nov

A swimming pool with lounge chairs and a wooden fence.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

14. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Jessica

AED 496

AED 563 total

includes taxes & fees

26 Oct - 27 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

A modern hotel lobby with seating areas, large windows, and a dining section.

A conference room with a long table, chairs, and a modern chandelier.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

15. Residence Inn Raleigh-Durham Airport/Brier Creek

16.6 km from Duke Regional Hospital

Janet

AED 512

AED 580 total

includes taxes & fees

31 Oct - 1 Nov

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A swimming pool with lounge chairs and a view of a building with large windows.

A hotel lobby with a reception desk, a modern abstract sculpture, and a patterned floor.

A courtyard with a pathway leading to a building with large windows and a yellow facade.

16. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 10.4 km from Duke Regional Hospital

Barbara

AED 302

AED 343 total

includes taxes & fees

1 Nov - 2 Nov

A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.

A bar area with wooden shelves, a chalkboard menu, and various bottles.

A covered porch with steps leading to a door, a brick wall, and a street lamp.

A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

17. The Colonial Inn, an Ascend Collection Hotel

18.6 km from Duke Regional Hospital

Matt W

AED 429

AED 487 total

includes taxes & fees

12 Nov - 13 Nov

A hotel room with two beds, a nightstand with a lamp, and a window with a view of trees.

A shelf stocked with various snack items, including boxed cereals and candy.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A gym with treadmills, elliptical machines, and exercise bikes.

18. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

16.9 km from Duke Regional Hospital

Nathaniel

AED 437

AED 513 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel reception area with two wooden reception desks, a large digital display wall, and a seating area with chairs.

A modern lobby with a fireplace, seating area, and wooden wall accents.

A modern restaurant with bar seating, a Starbucks sign, and a bar area with a counter and shelves.

19. Hilton Durham near Duke University

5.4 km from Duke Regional Hospital

Isaac

AED 419

AED 475 total

includes taxes & fees

26 Oct - 27 Oct

A long, narrow hallway with dark walls and wooden flooring.

A hotel room with a large bed, two bedside lamps, a chair, a desk, a heater, and a window with curtains.

A modern reception area with a reception desk, a seating area with chairs and a table, and a bookshelf with books.

20. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Nicole

AED 426

AED 484 total

includes taxes & fees

25 Oct - 26 Oct

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,001 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,000 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,003 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 579 reviews	View
JB Duke Hotel	9.4 Exceptional 736 reviews	View

Top Duke Regional Hospital Hotel Reviews

Millennium Hotel Durham

10/10 Excellent

"Nice place to stay"

Comfort Inn & Suites Durham near Duke University

8/10 Good

"The room we were given was very clean"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This is such a sweet cottage, so many details and there are instructions for EVERYTHING! NO guessing how to operate anything, they thought of it all,highly recommend to anyone! You can tell how much they care about every detail. I have stayed in many rentals and I can tell you this is a great deal for what you pay...very comfy beds, great linnens and the outdoor deck and front porch are a great bonus,plus there is a fireplace, but bring some starter kindling.Location is close to everything. Again, great value,it is really a little happy place,filled with little treasures!"

Courtyard Durham Near Duke University/Downtown

10/10 Excellent

"Staff is helpful and friendly"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"Super cute and clean!"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

10/10 Excellent

"!"

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

10/10 Excellent

"We loved it! Rooms were large and well decorated, everything was so cute! We played football in the yard and lots of other games. The neighborhood is really nice and safe too. Lots of kids and families. I would definitely stay again!"

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from AED 268

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Hampton Inn & Suites Durham University Medical Center

5. JB Duke Hotel

6. Washington Duke Inn & Golf Club

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

8. Hyatt House Raleigh / RDU / Brier Creek

9. Fairfield by Marriott Inn & Suites Durham

10. DoubleTree Suites by Hilton Raleigh - Durham

11. Courtyard Raleigh-Durham Airport/Brier Creek

12. Home2 Suites by Hilton Durham University Medical Center

13. Hilton Garden Inn Durham/University Medical Center

14. Hyatt Place Durham Southpoint

15. Residence Inn Raleigh-Durham Airport/Brier Creek

16. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

17. The Colonial Inn, an Ascend Collection Hotel

18. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG

19. Hilton Durham near Duke University

20. University Inn Durham next to Duke University Medical Center

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Millennium Hotel Durham

Comfort Inn & Suites Durham near Duke University

Cottage with Yard, Mins to Duke

Courtyard Durham Near Duke University/Downtown

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Everything within 1 mile

Unscripted Durham, Part of JDV by Hyatt

Durham Retreat: 10 mins from Duke & Downtown, 20 mins from RTP & RDU I Sleeps 8

Not Your Average Stay” +Glow Room by 9th St, Duke, Alexa,Games & WiFi + NEW! 2bd

Frequently asked questions