The Best Hotels Closest to Edisto Island Serpentarium in Edisto Island for 2026

Our top choices for Edisto Island Serpentarium hotels

Charleston Kiawah Island/Andell Inn

13.4 km from Edisto Island Serpentarium

Janet

AED 1,679 total

includes taxes & fees

28 Jun - 29 Jun

The Dunlin, Auberge Collection

16.4 km from Edisto Island Serpentarium

Sandi

AED 2,528 total

includes taxes & fees

29 Jun - 30 Jun

On the beach, sun loungers, beach umbrellas, beach towels

The Sanctuary at Kiawah Island Golf Resort

18.2 km from Edisto Island Serpentarium

Nathan

AED 3,071 total

includes taxes & fees

21 Jun - 22 Jun

The Breeze in Seabrook Island

9.9 km from Edisto Island Serpentarium

AED 2,686 total

includes taxes & fees

8 Jun - 9 Jun

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Top Edisto Island Serpentarium Hotel Reviews

Beach Access, Steps Away | Seaclusion by AvantStay

10/10 Excellent

"Great place we loved it all"

Water Front Edisto with Private Dock On Deep Creek overlooking the Ocean

10/10 Excellent

"My family and I were guests over Memorial Day weekend. The location allowed us to be away from the hustle and bustle of the front beach, but also close enough to enjoy the restaurants. There is plenty of space, but the majority of our time was spent on the back porch enjoying the breeze from the beach. We loved the access to the creek and Jeremy's Inlet."

Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi

10/10 Excellent

"Great location that never disappoints! One of the best places to relax and take in Gods creation. If you’re looking for a place to disconnect then you found your spot here."

3 bedroom elevated chic home tucked among the trees~ The Paper House

10/10 Excellent

"Great place to stay!!! Very clean and new appliances. We loved all the art on the walls. We spent most of our time on the porches looking at birds and wildlife! The neighbors dog (Jack) also strolls by for his morning pets. Close proximity to the boat launch and environmental center. The beach is a short drive as well. Definitely recommend!!!!"

Paradise Found | Ocean & Marsh Views

8/10 Good

"First, I want to make it clear. This is a great house. Really liked the layout and the views are amazing. Probably my favorite of all the homes we've stayed in over the past two decades. We had a great time. However, it does have opportunities for improvement which I've shared with the host. It's an older home and older homes can have their quirks. Very comfortable beds. Solid water pressure and hot water. Gorgeous views especially from the top deck and main living area. Everything you need for food prep. Also, the host team was incredibly easy to communicate with, responsive, and really helpful. We enjoyed the week emensely and will be staying here again."

4 Bedroom 2 Bath Ocean Front Vacation Rental on Edisto Beach

10/10 Excellent

"This is our second stay at No, This is Patrick and it just gets better each time. There have been some nice upgrades to the bathrooms. The kitchen is very well stocked with a wide variety of cookware, dishes, and appliances. You can't beat the location either! The covered deck was a great shelter since we had a pretty rainy week. We were able to still sit outdoors and watch the surf during the storms. We appreciate the beach chairs that were available as well. This is a special place for us to gather our grown children and their families from Montana and California."

Hotels near other Edisto Island Serpentarium attractions

Botany Bay Plantation

4.4/5 (25 reviews)

Explore the great outdoors at Botany Bay Plantation, a lovely green space in Edisto Island. Stroll along the beaches in this relaxing area, or seek out the fishing spots.

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Frequently asked questions

What's the area like around Edisto Island Serpentarium?

Edisto Island Serpentarium is located in an area of Edisto Island known for its beautiful beaches. You'll find 196 hotels and other accommodations within a few miles for a convenient home base.

How many hotels can I expect to find near Edisto Island Serpentarium?

Expedia has 196 hotels and other accommodations a few miles from Edisto Island Serpentarium.

If I need to cancel the hotel reservation for my stay near Edisto Island Serpentarium, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review the top deals on offer near Edisto Island Serpentarium.

Where can I learn more about changing or cancelling my trip in the area near Edisto Island Serpentarium?

To access more information about updating your stay near Edisto Island Serpentarium or cancelling it, go to https://www.expedia.com/service/.

What can I see and do near Edisto Island Serpentarium?

Attractions like With These Hands Gallery and Edisto Island Museum highlight the local culture. You might plan a visit to Edisto Beach State Park or Botany Bay Plantation Heritage Preserve and Wildlife Management Area while you're in the area. You might also stop by Plantation Course at Edisto, located 5.9 mi (9.5 km) from Edisto Island Serpentarium, or Bohicket Marina which is 7.9 mi (12.7 km) away.

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Hotels near popular Edisto Island Attractions

Hotels near Freshfields Village

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See a list of all hotels in Edisto Island

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Our top choices for Edisto Island Serpentarium hotels

Charleston Kiawah Island/Andell Inn

The Dunlin, Auberge Collection

The Sanctuary at Kiawah Island Golf Resort

The Breeze in Seabrook Island

Top Edisto Island Serpentarium Hotel Reviews

Beach Access, Steps Away | Seaclusion by AvantStay

Water Front Edisto with Private Dock On Deep Creek overlooking the Ocean

The Gulls Nest Beach House

Ocean Front Home with Breath Taking Views!

Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi

3 bedroom elevated chic home tucked among the trees~ The Paper House

Paradise Found | Ocean & Marsh Views

4 Bedroom 2 Bath Ocean Front Vacation Rental on Edisto Beach

Just Renovated! Welcome to I-Land Style 4BR, 2BTH OCEANFRONT on Edisto Beach

Hotels near other Edisto Island Serpentarium attractions

Botany Bay Plantation

With These Hands Gallery

Botany Bay Plantation Heritage Preserve and Wildlife Management Area

Edisto Island Museum

Edisto Beach State Park

beach near Spinnaker Beachhouses

Plantation Course at Edisto

Deep Water Vineyard

Frequently asked questions

Explore a world of travel with Expedia

Hotels near popular Edisto Island Attractions

Other Hotels near Edisto Island Serpentarium, Edisto Island

Explore more hotels

Find hotels near Edisto Island Serpentarium, Edisto Island from AED 1,679

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Edisto Island Serpentarium hotels

Charleston Kiawah Island/Andell Inn

The Dunlin, Auberge Collection

The Sanctuary at Kiawah Island Golf Resort

The Breeze in Seabrook Island

Top Edisto Island Serpentarium Hotel Reviews

Beach Access, Steps Away | Seaclusion by AvantStay

Hotels near other Edisto Island Serpentarium attractions

Botany Bay Plantation

Frequently asked questions

Explore a world of travel with Expedia

Hotels near popular Edisto Island Attractions

Other Hotels near Edisto Island Serpentarium, Edisto Island

Explore more hotels