Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
You can learn about the history of Florence with a stop at Brancacci Chapel. Stroll along the riverfront or visit the notable monuments in this vibrant area.
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Uffizi Gallery
You can study the exhibits at Uffizi Gallery, a museum with a story of its own, during your travels to Florence. Stroll along the riverfront or visit the churches in this vibrant area.
Ponte Vecchio
Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the notable monuments and stunning cathedral in this vibrant area.
Santo Spirito Hotel Deals
Hotel Horto Convento
Staff were super lovely, we were greeted by a very enthusiastic and full of character Giovanni who made us feel welcome. The place is very well kept, breakfast had a surprisingly wider variety of food for a continental breakfast, and is in a nice quiet part of Florence that is still accessible to ...
Reviewed on 22 November 2025
Palazzo Mannaioni Suites
Perfect stay
Reviewed on 18 November 2025
La Torre Del Cestello
What a great place. Great communication and staff. The apartment was lovely and large for our family. The location was very good and close to everything.
Reviewed on 26 November 2025
UNA Hotels Vittoria Firenze
Super nice reception staffs, everyone is so friendly and welcoming. But don’t like the red room decoration.
Reviewed on 5 November 2025
Casa Santo Nome di Gesù
I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced.
Reviewed on 11 November 2025
Oltrarno Splendid
It was Wonderful!!!
Reviewed on 16 November 2025
Other neighborhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Boboli Gardens.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Duomo
Via de' Calzaiuoli and Giotto's Campanile are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Via de' Calzaiuoli and Piazza della Repubblica are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Santo Spirito
- Places of interest
- Santo Spirito Hotels by Star Rating
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- Hotels in top Florence neighborhoods
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- Piazza Santo Spirito
- Porta Romana
- Santo Spirito Basilica
- Santa Maria della Carmine
- Brancacci Chapel
- Torrigiani Garden
- Piazza del Carmine
- Il Nabucco di Matteo Gabellini
- Church of St Felix
- Piazza di Santa Maria Novella
- Uffizi Gallery
- Ponte Vecchio
- Cathedral of Santa Maria del Fiore
- Piazza del Duomo
- Pitti Palace
- Piazza della Signoria
- Palazzo Vecchio
- Mugello Circuit
- Piazzale Michelangelo
- Fortezza da Basso
- Central Market
- Careggi Hospital
- Basilica of Santa Maria Novella
- Gallery of the Academy of Florence
- Antinori nel Chianti Classico
- Piazza Santa Croce
- Arno River
- Basilica of Santa Croce
- The Mall Luxury Outlet
- Piazza della Repubblica
- Piazza San Marco
- Via de' Tornabuoni
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