The Best Hotels Closest to Historic Main Street in St. Louis for 2026

A brick-paved street lined with historic buildings and a yellow fire hydrant.

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Our top choices for Historic Main Street hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A gym with treadmills, stationary bikes, and a weight machine.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

1. Drury Plaza Hotel St. Louis St. Charles

1.8 km from Historic Main Street

Robert

AED 499

AED 579 total

includes taxes & fees

4 Oct - 5 Oct

A brick building with a sign reading "Country Inn & Suites."

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

2. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District, 1 km from Historic Main Street

Roseanna

AED 523

AED 601 total

includes taxes & fees

12 Oct - 13 Oct

A modern kitchen with a central island, breakfast bar, and various appliances.

A hotel room with a large bed, a desk, a chair, and a window with a view.

A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.

An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.

3. Hampton Inn & Suites St. Charles Old Town Area

1.5 km from Historic Main Street

Daniel

AED 423

AED 508 total

includes taxes & fees

18 Oct - 19 Oct

A spacious indoor lobby with multiple seating areas, including round tables and sofas, and a central water feature.

A grand staircase with a wooden railing leading to a lower level, surrounded by potted plants and a patterned carpet.

A multi-story hotel with a central courtyard, a parking lot, and a green-roofed building.

A high-rise hotel with multiple floors, each featuring balconies with red railings and green plants. The interior includes a central atrium with a winding pathway and seating areas.

4. Embassy Suites by Hilton St. Louis St. Charles

2.1 km from Historic Main Street

Anonymous traveler

AED 509

AED 585 total

includes taxes & fees

11 Oct - 12 Oct

A large hotel with a prominent tower and multiple parking areas.

A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.

A bar area with a long counter, multiple screens, and seating.

A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.

5. Hollywood Casino & Hotel St. Louis

3 km from Historic Main Street

Nicole

AED 306

AED 466 total

includes taxes & fees

22 Oct - 23 Oct

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

A bar area with multiple seating arrangements, a stage, and a chandelier.

A bakery display case with various pastries and cakes.

6. Ameristar Casino Resort and Spa

1.4 km from Historic Main Street

Melissa

AED 548

AED 702 total

includes taxes & fees

13 Oct - 14 Oct

A modern cafe with a self-serve beverage station, a central island with seating, and large windows offering a view.

A modern lounge area with seating arrangements, tables, and hanging pendant lights.

A modern lounge area with sofas, tables, and chairs, featuring a mix of seating arrangements and a central coffee station.

7. Tru by Hilton St. Charles St. Louis, MO

2.1 km from Historic Main Street

Meridith

AED 509

AED 590 total

includes taxes & fees

11 Oct - 12 Oct

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A lobby with a wooden floor, a reception desk, a seating area with a red sofa, and a glass door leading to another room.

8. Comfort Suites St Charles - St Louis

1.5 km from Historic Main Street

Bryan

AED 333

AED 382 total

includes taxes & fees

19 Oct - 20 Oct

A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

A spacious lobby with a high ceiling, a seating area with sofas and chairs, a reception desk, and a television screen.

A spacious room with multiple tables and chairs, a reception desk, and a counter with various items.

A hotel room with a large bed, bedside tables with lamps, a flat-screen TV, and a large window with curtains.

9. Best Western Plus The Charles Hotel

1.5 km from Historic Main Street

Tony

AED 340

AED 394 total

includes taxes & fees

13 Oct - 14 Oct

A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and a view of the outside through large windows.

A hotel room with two beds, a desk with a television, a microwave, and a small refrigerator.

10. Elimwood Hotel, a Ramada by Wyndham

3.1 km from Historic Main Street

Rebecca

AED 306

AED 354 total

includes taxes & fees

4 Oct - 5 Oct

A restaurant with a long wooden table, cushioned seating, and decorative lanterns.

A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a patterned carpet.

A hotel room with a kitchenette, a sofa, a desk, and a large window with curtains.

A lobby with a checkered floor, a sofa, armchairs, a small table, and a water dispenser.

11. Holiday Inn St. Louis Arpt West-Earth City by IHG

2.9 km from Historic Main Street

Bryan

AED 378

AED 435 total

includes taxes & fees

29 Oct - 30 Oct

A spacious lobby with a reception desk, seating area, and a fireplace.

A living room with a beige sofa, a wooden coffee table, a patterned rug, a potted plant, and two framed pictures on the wall.

A dining area with round tables and white chairs, a kitchen counter with appliances, and a framed picture on the wall.

A hotel room with a large bed, two bedside lamps, a nightstand with a phone and alarm clock, and two framed floral pictures on the wall.

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1.6 km from Historic Main Street

Tom

AED 281

AED 326 total

includes taxes & fees

30 Sep - 1 Oct

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

13. Hyatt Place St. Louis/Chesterfield

15.9 km from Historic Main Street

Chelsea

AED 476

AED 552 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a central round table, two sofas, and a chandelier.

A buffet setup with various food items and a decorative vase of flowers.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

14. Drury Plaza Hotel St. Louis Chesterfield

15.8 km from Historic Main Street

Cassandra

AED 477

AED 554 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

15. Wingate by Wyndham St. Louis Airport

10.7 km from Historic Main Street

Mary

AED 343

AED 404 total

includes taxes & fees

30 Sep - 1 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

16. Pear Tree Inn St. Louis Airport

10.6 km from Historic Main Street

Murphy

AED 331

AED 389 total

includes taxes & fees

4 Oct - 5 Oct

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

17. Drury Inn & Suites St. Louis Airport

11.3 km from Historic Main Street

Lakeshia

AED 422

AED 496 total

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern lobby with blue seating, a reception desk, and large windows.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

18. Hyatt Select St. Louis Airport

12 km from Historic Main Street

Will

AED 404

AED 497 total

includes taxes & fees

8 Oct - 9 Oct

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A snack vending machine with various snack options.

19. Hampton Inn By Hilton St Louis Airport

11.7 km from Historic Main Street

Leia

AED 473

AED 565 total

includes taxes & fees

8 Oct - 9 Oct

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A modern lobby with a reception desk, seating area, and a dining section.

A Holiday Inn Express hotel with a modern design, featuring a covered entrance and multiple windows.

A hotel room with two beds, a desk, a blue sofa, and a TV.

20. Holiday Inn Express & Suites St Peters by IHG

15.7 km from Historic Main Street

Serah

AED 433

AED 521 total

includes taxes & fees

4 Oct - 5 Oct

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Compare popular hotels close to Historic Main Street

Property	Property class	Guest rating
Drury Plaza Hotel St. Louis St. Charles	9.6 Exceptional 1,002 reviews	View
Country Inn & Suites by Radisson, St. Charles Historic District	9.4 Exceptional 1,098 reviews	View
Hampton Inn & Suites St. Charles Old Town Area	9.0 Wonderful 741 reviews	View
Embassy Suites by Hilton St. Louis St. Charles	8.8 Excellent 1,008 reviews	View
Hollywood Casino & Hotel St. Louis	8.6 Excellent 2,246 reviews	View

Top Historic Main Street Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District

8/10 Good

"nice size free parking spots in the garage. Breakfast was slim. one morning just had sausage and eggs and waffles. next morning had biscuits and gravy and waffles. hotel was clean staffing was friendly. location was good. The cookies were delicious."

Ameristar Casino Resort and Spa

10/10 Excellent

"Very nice hotel. Staff very friendly."

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent

"They were excellent hosts and great communication!! I highly recommend this house!"

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

8/10 Good

"Great accessibility to shops and restaurants"

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent

"The Host ensured our needs were taken care. Perfect location!"

Driftwood Den | Boho 2BR | Dog-Friendly

10/10 Excellent

"Clean, easy parking, easy egress and ingress"

Stylish 2BR Retreat - Concrete & Canopy

10/10 Excellent

"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent

"Everything was exactly as described. St. Charles is an awesome place!"

The Global Getaway | World-Inspired 2-Bedroom Stay

10/10 Excellent

"Perfect location to Main Street.Hosts were easy to communicate with.No issues with the unit"

Other attractions near Historic Main Street

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.

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A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)

You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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First Missouri State Capitol Historic Site

8.2/10 (25 reviews)

You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.

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Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)

You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lindenwood University

8.6/10 (183 reviews)

Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St Charles Convention Center

8.4/10 (223 reviews)

After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.

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Frequently asked questions

What's the area like around Historic Main Street?

Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 104 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Historic Main Street?

Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.

How many hotels are there near Historic Main Street?

Expedia has 104 hotels and other accommodations within a mile from Historic Main Street.

If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.

Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?

For more information about rescheduling or cancelling your stay near Historic Main Street, click here.

What can I see and do near Historic Main Street?

Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

Find hotels near Historic Main Street, St. Louis from AED 326

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Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

2. Country Inn & Suites by Radisson, St. Charles Historic District

3. Hampton Inn & Suites St. Charles Old Town Area

4. Embassy Suites by Hilton St. Louis St. Charles

5. Hollywood Casino & Hotel St. Louis

6. Ameristar Casino Resort and Spa

7. Tru by Hilton St. Charles St. Louis, MO

8. Comfort Suites St Charles - St Louis

9. Best Western Plus The Charles Hotel

10. Elimwood Hotel, a Ramada by Wyndham

11. Holiday Inn St. Louis Arpt West-Earth City by IHG

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

13. Hyatt Place St. Louis/Chesterfield

14. Drury Plaza Hotel St. Louis Chesterfield

15. Wingate by Wyndham St. Louis Airport

16. Pear Tree Inn St. Louis Airport

17. Drury Inn & Suites St. Louis Airport

18. Hyatt Select St. Louis Airport

19. Hampton Inn By Hilton St Louis Airport

20. Holiday Inn Express & Suites St Peters by IHG

Compare popular hotels close to Historic Main Street

Top Historic Main Street Hotel Reviews

Country Inn & Suites by Radisson, St. Charles Historic District

Ameristar Casino Resort and Spa

The St. Charles Guest House, lovely historic home, fun for families and groups

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

The Rustic Revival | Charming 2BR Retreat

Driftwood Den | Boho 2BR | Dog-Friendly

Stylish 2BR Retreat - Concrete & Canopy

The Foundry Flat | Industrial-Inspired 2-Bedroom

The Global Getaway | World-Inspired 2-Bedroom Stay

Other attractions near Historic Main Street

Frontier Park

Katy Trail

First Missouri State Capitol Historic Site

Missouri Artists on Main

Lewis & Clark Boathouse and Nature Center

Frenchtown Heritage Museum

Lindenwood University

St Charles Convention Center

Frequently asked questions