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Find hotels in South Central Houston, Houston
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Our top choices for South Central Houston hotels
1. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,212 reviews)
"great location and the hotel is quite comfortable"
Juan
The price is AED 531
AED 661 total
includes taxes & fees
11 Oct - 12 Oct
2. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterSouth Central Houston
8.6 out of 10, Excellent, (2,166 reviews)
"Beautiful Hotel and excellent Service"
olga
The price is AED 389
AED 459 total
includes taxes & fees
11 Oct - 12 Oct
3. Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,006 reviews)
"Nice hotel"
Deul
The price is AED 885
AED 1,205 total
includes taxes & fees
8 Oct - 9 Oct
4. InterContinental Houston by IHG
InterContinental Houston by IHGSouth Central Houston
9.4 out of 10, Exceptional, (1,008 reviews)
"Great stay!"
Luke
The price is AED 599
AED 774 total
includes taxes & fees
25 Oct - 26 Oct
5. Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,002 reviews)
"They are very accommodating. Easy access to Houston Methodist Hoptial."
Melanie
The price is AED 625
AED 850 total
includes taxes & fees
17 Oct - 18 Oct
6. Downtowner Inns - Houston Downtown
Downtowner Inns - Houston DowntownSouth Central Houston
9.2 out of 10, Wonderful, (244 reviews)
"Second time stay here. Lovely place"
Jaelon
The price is AED 328
AED 384 total
includes taxes & fees
29 Sep - 30 Sep
7. Sentral Forme Houston
Sentral Forme HoustonSouth Central Houston
9.0 out of 10, Wonderful, (87 reviews)
"Great place to stay!"
Keeshaun
The price is AED 590
AED 798 total
includes taxes & fees
28 Sep - 29 Sep
8. La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&BSouth Central Houston
9.8 out of 10, Exceptional, (599 reviews)
"I loved this property and the people who owned it are awesome!! Delicious breakfast, great location..clean and stylish rooms. Great amenitie!!!. Highly recommended!!"
Charles
The price is AED 631
AED 738 total
includes taxes & fees
30 Sep - 1 Oct
9. Americas Best Value Inn Medical Center Downtown
Americas Best Value Inn Medical Center DowntownSouth Central Houston
8.0 out of 10, Very good, (1,001 reviews)
"Clean room, comfortable stay"
Susanne
The price is AED 272
AED 318 total
includes taxes & fees
28 Sep - 29 Sep
10. DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston
8.4 out of 10, Very good, (681 reviews)
"Great hotel"
Brandon
The price is AED 479
AED 560 total
includes taxes & fees
11 Oct - 12 Oct
11. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults OnlySouth Central Houston
9.6 out of 10, Exceptional, (221 reviews)
"The room was very clean, the staff was just great and the breakfast was very good! The Parking was a little difficult, but it was very safe!"
Walter
The price is AED 646
AED 811 total
includes taxes & fees
29 Sep - 30 Sep
12. Hilton University of Houston
Hilton University of HoustonSouth Central Houston
9.0 out of 10, Wonderful, (982 reviews)
"Pretty amazing stay"
DELISA
The price is AED 569
AED 666 total
includes taxes & fees
4 Oct - 5 Oct
13. Wanderstay Boutique Hotel
Wanderstay Boutique HotelSouth Central Houston
9.8 out of 10, Exceptional, (80 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
Sharon
The price is AED 509
AED 596 total
includes taxes & fees
28 Sep - 29 Sep
14. Modern 3BR Near UH Downtown Toyota Center NRG
Modern 3BR Near UH Downtown Toyota Center NRGSouth Central Houston
The price is AED 430
AED 3,227 total
includes taxes & fees
28 Sep - 29 Sep
15. Scott Inn Suites - Downtown Houston
Scott Inn Suites - Downtown HoustonSouth Central Houston
8.4 out of 10, Very good, (47 reviews)
"Nice staff, good clean room and close to public transportation"
Sergio
The price is AED 239
AED 298 total
includes taxes & fees
5 Oct - 6 Oct
16. Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood BlSouth Central Houston
6.0 out of 10, (1,003 reviews)
"The perfect place to stay!"
Maria Fernanda
The price is AED 284
AED 334 total
includes taxes & fees
4 Oct - 5 Oct
17. Southmore Boulevard Motel
Southmore Boulevard MotelSouth Central Houston
5.6 out of 10, (245 reviews)
"Very sweet lady I will be back"
LaKeara
The price is AED 215
AED 251 total
includes taxes & fees
9 Oct - 10 Oct
18. Wanderstay Houston Hostel
Wanderstay Houston HostelSouth Central Houston
8.2 out of 10, Very good, (214 reviews)
"Excellent stay experience"
Binkeung
The price is AED 190
AED 222 total
includes taxes & fees
28 Sep - 29 Sep
19. Golden Motel Near Houston Medical Center
Golden Motel Near Houston Medical CenterSouth Central Houston
2.0 out of 10, (4 reviews)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
Jacari
The price is AED 257
AED 316 total
includes taxes & fees
10 Oct - 11 Oct
20. Affordable Eado Stay Near Downtown Houston
Affordable Eado Stay Near Downtown HoustonSouth Central Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in South Central Houston
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 La Maison in Midtown an urban B&B | 9.8 Exceptional 599 reviews | View | ||||||
 Wanderstay Boutique Hotel | 9.8 Exceptional 80 reviews | View | ||||||
 Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only | 9.6 Exceptional 221 reviews | View | ||||||
 The Westin Houston Medical Center/Museum District | 9.2 Wonderful 1,212 reviews | View | ||||||
 Downtowner Inns - Houston Downtown | 9.2 Wonderful 244 reviews | View |
Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Top South Central Houston Hotel Reviews
La Maison in Midtown an urban B&B
10/10 Excellent
