What's it like in South Central Houston?

Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Be sure to check out TDECU Stadium and Children's Museum of Houston as part of your South Central Houston travel plans.

What's the best accommodation in South Central Houston?

Based on our traveler data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel is a short 6-minute walk from Rice University, and it offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and The Westin Houston Medical Center/Museum District .

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1271 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.

Where can I learn more about changing or cancelling my trip to South Central Houston?

To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/ .

What is there to do around this Houston neighborhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Twilight Epiphany Skyspace. TDECU Stadium and Children's Museum of Houston are some other stops to visit in the neighborhood. Daikin Park and Toyota Center are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

Top South Central Houston Hotels

A water feature with multiple tiers and a circular viewing platform at the top.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for South Central Houston hotels

Outdoor pool, free cabanas, pool umbrellas

1. The Westin Houston Medical Center/Museum District

South Central Houston

Juan

AED 661 total

includes taxes & fees

26 Sep - 27 Sep

2. Hilton Houston Plaza/Medical Center

South Central Houston

olga

AED 459 total

includes taxes & fees

1 Oct - 2 Oct

3. InterContinental Houston by IHG

South Central Houston

Luke

AED 817 total

includes taxes & fees

18 Oct - 19 Oct

Premium bedding, pillowtop beds, minibar, in-room safe

4. Hotel Zaza Houston Museum District

South Central Houston

Deul

AED 1,263 total

includes taxes & fees

8 Oct - 9 Oct

5. Houston Marriott Medical Center/Museum District

South Central Houston

Valencia

AED 889 total

includes taxes & fees

2 Oct - 3 Oct

Laptop workspace, blackout drapes, soundproofing

6. Downtowner Inns - Houston Downtown

South Central Houston

AED 388 total

includes taxes & fees

7 Oct - 8 Oct

South Central Houston

AED 725 total

includes taxes & fees

27 Sep - 28 Sep

11. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

South Central Houston

Shelly

AED 811 total

includes taxes & fees

24 Sep - 25 Sep

12. Hilton University of Houston

South Central Houston

DELISA

AED 666 total

includes taxes & fees

29 Sep - 30 Sep

13. Extended Stay America Suites Houston Med Ctr Braeswood Bl

South Central Houston

Maria Fernanda

AED 334 total

includes taxes & fees

25 Sep - 26 Sep

14. Modern 3BR Near UH Downtown Toyota Center NRG

South Central Houston

AED 3,227 total

includes taxes & fees

24 Sep - 25 Sep

Iron/ironing board (on request), bed sheets

South Central Houston

AED 1,648 total

includes taxes & fees

24 Sep - 25 Sep

View all properties

Compare popular hotels in South Central Houston

Property	Property class	Guest rating
Downtowner Inns - Houston Downtown	2.0 star property	9.2 Wonderful 242 reviews	View
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only	3.5 star property	9.6 Exceptional 220 reviews	View
InterContinental Houston by IHG	4.0 star property	9.4 Exceptional 1,006 reviews	View
Sentral Forme Houston	4.5 star property	9.0 Wonderful 83 reviews	View
Hotel Zaza Houston Museum District	4.5 star property	9.2 Wonderful 1,008 reviews	View

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.

A sculpture garden with abstract art pieces in a city park.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

See properties

A person walking in front of a building with a brick facade and three arched windows.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

See properties

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

See properties

A modern building with a covered outdoor area and a circular garden feature.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

See properties

A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

See properties

Top South Central Houston Hotel Reviews

The Westin Houston Medical Center/Museum District

10/10 Excellent

"I had a great stay! I checked in Saturday night after attending a wine festival and needed a convenient place to stay before work on Sunday. The hotel was right across the street from my job, which made it the perfect location. The room was clean, comfortable, and well-maintained, and the shower was spotless. The complimentary bottle of wine was a thoughtful touch and made the stay even more enjoyable. I would definitely stay here again!"

DoubleTree by Hilton Houston Medical Center Hotel & Suites

10/10 Excellent

"Staff sooo helpful and nice. I am from NE so hospitality so different. Everyone I met was great. I felt genuine welcoming care with anything I needed. They have an hourly scheduled shuttle to the Medical Centers which is so convenient and helpful as I was visiting an ill family member and didn't know my way around. It was hot too so abit of respite from heat. The breakfast staff was so nice -you felt like your grandma was telling you to relax and eat... they brought me tea, checked on everyone, cleaned up to make space, remembered guests..... Awesome cookies!"

Find hotels in South Central Houston, Houston

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for South Central Houston hotels

1. The Westin Houston Medical Center/Museum District

2. Hilton Houston Plaza/Medical Center

3. InterContinental Houston by IHG

4. Hotel Zaza Houston Museum District

5. Houston Marriott Medical Center/Museum District

6. Downtowner Inns - Houston Downtown

7. Americas Best Value Inn Medical Center Downtown

8. DoubleTree by Hilton Houston Medical Center Hotel & Suites

9. La Maison in Midtown an urban B&B

10. Sentral Forme Houston

11. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

12. Hilton University of Houston

13. Extended Stay America Suites Houston Med Ctr Braeswood Bl

14. Modern 3BR Near UH Downtown Toyota Center NRG

15. Scott Inn Suites - Downtown Houston

16. Southmore Boulevard Motel

17. Wanderstay Houston Hostel

18. Golden Motel Near Houston Medical Center

19. The Oasis Checkmate HTX Rooftop

20. Affordable Eado Stay Near Downtown Houston

Compare popular hotels in South Central Houston

Where to stay in South Central Houston

Downtown Houston

The Galleria

Texas Medical Center

Montrose

Houston Central Business District

Top South Central Houston Hotel Reviews

The Westin Houston Medical Center/Museum District

Frequently asked questions