Find hotels in South Central Houston, Houston from AED 241

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Check prices for these dates

This weekend
22 May - 24 May
Next weekend
29 May - 31 May

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Our top choices for South Central Houston hotels

Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,156 reviews)
"Fantastic reasonably priced property."
United States
William
The price is AED 592
AED 737 total
includes taxes & fees
22 May - 23 May
The Westin Houston Medical Center/Museum District
Terrace/patio

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very Good, (1,922 reviews)
"Breakfast was wonderful and the front desk staff were very helpful."
United States
Reta
The price is AED 400
AED 473 total
includes taxes & fees
24 May - 25 May
Hilton Houston Plaza/Medical Center
Dinner served, American cuisine

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,001 reviews)
"Right in the center of the Medical District. Didn’t even have to go outside to get to my wife’s appointment. "
United States
Dominick
The price is AED 691
AED 928 total
includes taxes & fees
31 May - 1 Jun
Houston Marriott Medical Center/Museum District
Exterior

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,000 reviews)
"Modern, elegant great restaurant"
United States
Kathryn
The price is AED 554
AED 722 total
includes taxes & fees
24 May - 25 May
InterContinental Houston by IHG
Exterior detail

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (35 reviews)
"Verry nice and staff was very helpful. Will stay again"
United States
Carolyn
The price is AED 657
AED 877 total
includes taxes & fees
24 May - 25 May
Sentral Forme Houston
Laptop workspace, blackout drapes, soundproofing, iron/ironing board

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (138 reviews)
"Great place. The staff is very friendly and the place is clean."
United States
Fernando
The price is AED 301
AED 352 total
includes taxes & fees
21 May - 22 May
Downtowner Inns - Houston Downtown
Premium bedding, pillowtop beds, minibar, in-room safe

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,001 reviews)
"Beautiful hotel, with wonderful service. We enjoyed the restaurant, the art and the pool!"
United States
Shahriyor
The price is AED 715
AED 1,002 total
includes taxes & fees
25 May - 26 May
Hotel Zaza Houston Museum District
Breakfast and dinner served

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (584 reviews)
"Staff was wonderful "
United States
Lynn
The price is AED 450
AED 526 total
includes taxes & fees
24 May - 25 May
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Reception

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very Good, (1,008 reviews)
"Convenient location and comfortable room."
United States
Rogelio
The price is AED 259
AED 303 total
includes taxes & fees
21 May - 22 May
Americas Best Value Inn Medical Center Downtown
Exterior

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (572 reviews)
"We felt welcome from the moment we walked in. The owners are so hospitable and the place such a delight. Loved the generous breakfast and ambiance- great parking as well!"
United States
Carolina
The price is AED 592
AED 692 total
includes taxes & fees
25 May - 26 May
La Maison in Midtown an urban B&B
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (212 reviews)
"Beautiful place and wonderful management. Would definitely stay again! "
United States
Shelly
The price is AED 760
AED 945 total
includes taxes & fees
22 May - 23 May
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Lobby

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (947 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
United States
Ricardo
The price is AED 535
AED 625 total
includes taxes & fees
26 May - 27 May
Hilton University of Houston
Apartment, Smoking | 2 bedrooms

2-bedroom - Equipped Kitchen - Gated Parking

2-bedroom - Equipped Kitchen - Gated Parking
2.0 star property
South Central Houston
The price is AED 257
AED 2,319 total
includes taxes & fees
26 May - 27 May
2-bedroom - Equipped Kitchen - Gated Parking
Reception

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (73 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
United States
Sharon
The price is AED 442
AED 517 total
includes taxes & fees
26 May - 27 May
Wanderstay Boutique Hotel
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout drapes, free WiFi

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (238 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is AED 206
AED 241 total
includes taxes & fees
21 May - 22 May
Southmore Boulevard Motel
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,019 reviews)
"Love the pet friendly property"
United States
Nelda
The price is AED 264
AED 310 total
includes taxes & fees
21 May - 22 May
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Reception

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (1 review)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is AED 192
AED 244 total
includes taxes & fees
1 Jun - 2 Jun
Golden Motel Near Houston Medical Center
Interior

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very Good, (200 reviews)
"it was a great experience, staff was kind and helpful. "
United States
James
The price is AED 224
AED 262 total
includes taxes & fees
21 May - 22 May
Wanderstay Houston Hostel
Apartment, Smoking | 1 bedroom

Gated Studio Near Downtown Houston and NRG

Gated Studio Near Downtown Houston and NRG
2.0 star property
South Central Houston
The price is AED 357
AED 2,161 total
includes taxes & fees
25 May - 26 May
Gated Studio Near Downtown Houston and NRG
House | Private kitchen

Downtown Houston 3BR Bachelorette Escape

Downtown Houston 3BR Bachelorette Escape
2.0 star property
South Central Houston
9.8 out of 10, Exceptional, (6 reviews)
"Everything was great. Look no further and book this property. "
United States
Iesheal
Downtown Houston 3BR Bachelorette Escape
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Laptop workspace, blackout drapes, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
138 reviews
View
Reception
Wanderstay Boutique Hotel
3.0 star property
9.8
Exceptional
73 reviews
View
Outdoor pool
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
9.6
Exceptional
212 reviews
View
Premium bedding, pillowtop beds, minibar, in-room safe
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,001 reviews
View
Exterior
InterContinental Houston by IHG
4.0 star property
9.2
Wonderful
1,000 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Houston_TexasChildrensHospital_553248635389801905_9

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4/10 Poor
"The lobby was beautiful and very well maintained, but unfortunately the actual room did not match the price point. For nearly $200 a night, the room felt underwhelming and unfinished. It smelled strongly of fresh paint, and early in the morning there were workers banging on the walls, which made it difficult to rest. The bed was by far the biggest disappointment. The mattress had no support whatsoever and sagged badly in the middle. I woke up with significant back pain and did not sleep comfortably at all. The front desk experience also left a lot to be desired. The staff member assisting me, Beatrice, came across as rude and impatient. She repeatedly interrupted me while I was speaking and did not seem welcoming or hospitable. Overall, while the hotel was clean and the lobby looked impressive, the guest room experience did not justify the cost. It honestly feels like more effort is being put into appearances in the common areas than into the comfort and quality of the rooms themselves. I expected much more from the Hilton brand and left very disappointed."
Camila 1-night trip
Posted 2 hours ago
Hilton Houston Plaza/Medical Center

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Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Be sure to check out Children's Museum of Houston and Houston Natural Science Museum as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveler data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and Sentral Forme Houston.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1157 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Children's Museum of Houston and Houston Natural Science Museum are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.