South Central Houston, TX
Houston
Visit South Central Houston
Popular places to visit
Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's lively festivals and fascinating museums.
University of Houston
Enjoy the collegiate vibe around University of Houston, a top university in Houston. Experience the acclaimed art scene and great live music in this vibrant area.
Houston Zoo
Why not visit the native and exotic animals at Houston Zoo and see why this is a popular attraction in Houston? Experience the area's fascinating museums and lively festivals.
Houston Natural Science Museum
You can spend time studying the exhibits at Houston Natural Science Museum in Houston. Experience the area's fascinating museums and great live music.
Houston Museum of Fine Arts
You can spend time exploring the galleries in Houston Museum of Fine Arts during your trip to Houston. Experience the area's entertainment choices and fascinating museums.
Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's fascinating museums and lively festivals.
South Central Houston Hotel Deals
Hotel Zaza Houston Museum District
Great staff, they did a really nice job of taking care of my wife and I!
Reviewed on 12 November 2025
Hilton Houston Plaza/Medical Center
All was good. The parking was not free. $20 to park.
Reviewed on 10 November 2025
InterContinental Houston by IHG
Always an incredible experience staying in this hotel
Reviewed on 28 October 2025
Downtowner Inns - Houston Downtown
Arrived 2 hours before check-in, but got a room. Clean and nice.
Reviewed on 9 November 2025
The Westin Houston Medical Center/Museum District
Everything about my stay was great and everything went smoothly. Valet was efficient and careful, check-in was easy and the concierge kindly granted my request for a quiet room away from traffic and noise. Room was clean, so nice, and EVERYTHING WORKED (a rarity these days). Terrace 54 Restaurant ...
Reviewed on 10 November 2025
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Great service
Reviewed on 26 October 2025
Check South Central Houston hotel availability
Other neighborhoods around South Central Houston
Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.
Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.
Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
South Central Houston, TX
- MD Anderson Cancer Center
- Rice University
- University of Houston
- Houston Zoo
- Houston Natural Science Museum
- Texas Southern University
- Houston Methodist Hospital
- Texas Children's Hospital
- Houston Museum of Fine Arts
- Children's Museum of Houston
- Hermann Park
- Main Street Theater - Rice Village
- Memorial Hermann Hospital
- Midtown Arts and Theater Center Houston
- Continental Club
- Harris Health System - Ben Taub General Hospital
- Chi St. Lukes Health Baylor College Of Medicine Medical Center
- Conrad Hilton Archives
- Shriners Hospitals For Children
- Health Museum
- Holocaust Museum Houston
- Ensemble Theatre
- Miller Outdoor Theater
- Buffalo Soldiers National Museum
- Hermann Drive Surgical Hospital
