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Check prices for these dates

Tonight
12 Aug - 13 Aug
Tomorrow
13 Aug - 14 Aug
This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

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Our top choices for Lyon hotels

Breakfast included
Hotel
Reserve now, pay later
Airport shuttle included
Hostel/Backpacker accommodation

1. Travelers Hotel

Travelers Hotel
Clarksdale
United States
Katrina
AED 555
AED 605 total
includes taxes & fees
27 Aug - 28 Aug
Travelers Hotel

2. Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel
Clarksdale
United States
Rydell
AED 407
AED 444 total
includes taxes & fees
13 Aug - 14 Aug
Auberge Clarksdale Blues Hostel

3. Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale
Clarksdale
United States
Kartreace
AED 294
AED 320 total
includes taxes & fees
13 Aug - 14 Aug
Americas Best Value Inn & Suites Clarksdale

4. Hampton Inn Clarksdale

Hampton Inn Clarksdale
Clarksdale
United States
William Owen
AED 479
AED 522 total
includes taxes & fees
23 Aug - 24 Aug
Hampton Inn Clarksdale

5. Quality Inn Clarksdale

Quality Inn Clarksdale
Clarksdale
United States
Sherra
AED 307
AED 335 total
includes taxes & fees
8 Sep - 9 Sep
Quality Inn Clarksdale
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Top Lyon Hotel Reviews

Travelers Hotel

Travelers Hotel

10/10 Excellent
"It was clean, within walking distance of blues club, museum and restaurants."
Carolyn 1-night trip
Posted 5 days ago
Travelers Hotel
Sunset Log Cabin

Sunset Log Cabin

10/10 Excellent
"Perfect porch, perfect bed"
Jon H. 1-night trip
Posted 6 days ago
Sunset Log Cabin
Quality Inn Clarksdale

Quality Inn Clarksdale

8/10 Good
"All good. Staff is a big plus."
John 1-night trip
Posted 6 days ago
Quality Inn Clarksdale
Only a mile from historic downtown Clarksdale!

Only a mile from historic downtown Clarksdale!

10/10 Excellent
"Great spot. Excellent host"
Todd G. 2-night trip
Posted 2 weeks ago
Only a mile from historic downtown Clarksdale!
Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale

8/10 Good
"Receptionist at least knew were places were. Rare"
tony 1-night trip
Posted 3 weeks ago
Americas Best Value Inn & Suites Clarksdale
Cottage on riverbank one mile from Clarksdale in gated community

Cottage on riverbank one mile from Clarksdale in gated community

10/10 Excellent
"The property was very clean, comfortable and check in was so easy, the hospitality was amazing, we really enjoyed ourselves and will be visiting again!!!"
Bridget I. 3-night trip
Posted 3 weeks ago
Cottage on riverbank one mile from Clarksdale in gated community
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

10/10 Excellent
"The location was so perfect for us on our volunteer trip. The house was clean and easily accessible. Kitchen stocked with everything you need. Great shower. We loved the house and the front porch too. Parking is easy. The owner communicated so well in regards to any questions we had. She told us places to eat on days when a lot of restaurant were closed, told us about the farmers market and where to find groceries. Thank you."
Neil g. 5-night trip
Posted 3 weeks ago
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

10/10 Excellent
"We had an incredible stay at this historic mansion in Clarksdale! Our large group had more than enough room to spread out comfortably, and the house itself is full of charm, character, and history. It was the perfect place to gather together while still having plenty of space for everyone.The pool was one of the highlights of our trip. It was large, well-maintained, and the perfect place to relax after a day of exploring.Our host was fantastic from start to finish. They were incredibly friendly, quick to respond to any questions, and gave us wonderful recommendations for local restaurants, attractions, and hidden gems that made our trip even more memorable.If you have the chance, be sure to spend some time exploring downtown Clarksdale. It's packed with history, incredible music culture, and so many unique places to discover. If you're a fan of the blues, this town is an absolute must-visit.We couldn't have asked for a better place to stay and would absolutely recommend it to anyone visiting Clarksdale, whether you're traveling with family, friends, or a large group. We would gladly stay here again!"
Nicole S. 8-night trip
Posted 1 month ago
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time
Casa D’Amore!!!!  Adorable home less than 1/2 mile from downtown Clarksdale

Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

8/10 Good
"While the house was older, updating was done well by the owners. The homes around it and the neighborhood surrounding it leave a lot to be desired. It is definitely an oasis in the middle of the desert. We enjoyed our stay."
Terrence 4-night trip
Posted 2 months ago
Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

More cheap stays in Lyon

Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS
AED 294
AED 320 total
13 Aug - 14 Aug
includes taxes & fees
6/10 (427 reviews)
Americas Best Value Inn & Suites Clarksdale
Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
AED 307
AED 335 total
8 Sep - 9 Sep
includes taxes & fees
7.2/10 Good! (766 reviews)
Quality Inn Clarksdale
Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel

164 Delta Ave Clarksdale MS
AED 407
AED 444 total
13 Aug - 14 Aug
includes taxes & fees
Auberge Clarksdale Blues Hostel
Hampton Inn Clarksdale

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS
AED 479
AED 522 total
23 Aug - 24 Aug
includes taxes & fees
Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

212 3rd St Clarksdale MS
AED 555
AED 605 total
27 Aug - 28 Aug
includes taxes & fees
9.8/10 Exceptional! (313 reviews)
Travelers Hotel
High Cotton Condos

High Cotton Condos

249 Delta Ave Clarksdale MS
Get rates
8.8/10 Excellent! (6 reviews)
High Cotton Condos

Frequently asked questions

What's the best place for a stay in Lyon?
Quality Inn Clarksdale, located 3.2 mi (5.2 km) from the heart of Lyon, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Hampton Inn Clarksdale and Travelers Hotel. See all available top hotels, or vacation rentals in Lyon.
What are some of the best vacation rentals that Lyon has to offer?
The Sunflower Penthouse on the River in Clarksdale: This vacation home rental outside of Lyon is located on a river and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Make the most of the books in this rental home to help you unwind. See all vacation rentals in Lyon.
If I need to cancel my hotel reservation in Lyon, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Lyon.
Where can I learn more about changing or cancelling my trip to Lyon?
For additional details about updating your trip to Lyon or cancelling it, head over to our customer service page.
What is staying in Lyon like?
Travelers to Lyon will find plenty to explore and enjoy. There are 32 hotels and other accommodations in the surrounding area. Find out more about Lyon.
What should I do while I'm visiting Lyon?
Places to visit in the wider area include Delta Blues Museum, Ground Zero Blues Club, and Rock N' Roll & Blues Heritage Museum. You'll also find The Crossroads and Hambone Art Gallery in the area. Check out what more to see and do in Expedia's Lyon guide.
What's the seasonal weather like in Lyon?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 47°F. The rainiest months in Lyon are April, March, May, and December, with each month seeing an average of 7 inches of rainfall.