Top 10 Hotels in Murphy, MO from AED 335 - Competitive Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Murphy

Pet friendly

Apartment

Condo

Pool

Hot tub

Cottage

Family friendly

Cabin

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Murphy hotels

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

A modern hotel with a prominent 'La Quinta' sign, large windows, and a covered entrance area.

A modern hotel lobby with a cityscape view, a reception desk, and ambient lighting.

A modern hotel lobby with a seating area, a desk, and large windows offering a view of the outside.

1. La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis

Cheryl

AED 350

AED 406 total

includes taxes & fees

4 Oct - 5 Oct

A modern dining area with multiple tables and chairs, recessed ceiling lights, and a kitchen in the background.

An indoor swimming pool with tiled flooring, a pool ladder, and lounge chairs.

An outdoor patio area with a fire pit, black metal chairs, and a blue umbrella.

A gym with treadmills, elliptical machines, and a mirrored wall.

2. Best Western Plus Fenton

Fenton

Brian

AED 356

AED 411 total

includes taxes & fees

4 Oct - 5 Oct

A modern interior with hanging pendant lights, large windows, and a view of the outside.

A hotel indoor pool area with a hot tub, seating, and a view of the outdoors.

A modern hotel with a covered entrance, brick facade, and a parking area.

A modern hotel lobby with a high ceiling, multiple hanging pendant lights, a reception desk with a Missouri US 66 sign, and large windows allowing natural light.

3. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Dashaun

AED 328

AED 379 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel lobby with a high ceiling, a central seating area with sofas and a coffee table, and a flat-screen TV mounted on the wall.

An indoor swimming pool with a hot tub, lounge chairs, and a tiled floor.

A modern hotel breakfast area with a central island, buffet setup, and a large window providing a view.

A spacious lobby with a high ceiling, a flat-screen TV mounted on the wall, and a seating area with sofas and ottomans.

4. Drury Inn & Suites Southwest St. Louis

Valley Park

Randy

AED 422

AED 494 total

includes taxes & fees

7 Oct - 8 Oct

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

A hotel room with a large bed, a bedside lamp, a telephone, a mirror, and a bathroom with a sink and towel rack.

A modern bathroom with a large mirror, white vanity, and a bathtub.

5. The Wildwood Hotel

Wildwood

Ryan

AED 304

AED 354 total

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with multiple seating areas, a central coffee table, and artwork on the walls.

A kitchen with wooden cabinets, a black countertop, and a microwave. There is a table and chairs set up for dining.

A hotel room with two beds, a nightstand with a lamp, a painting on the wall, and a window with curtains.

A hotel with multiple floors, a prominent 'Best Western' sign, and a parking area with several cars.

6. Best Western St. Louis-Kirkwood Route 66

Kirkwood

Mildred

AED 338

AED 395 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, a dresser, and a TV.

A swimming pool with clear blue water, surrounded by lounge chairs and a fenced area.

Two white cups of coffee on a reflective black surface with a glass of milk in the background.

A modern building with a brick facade and a green roof.

7. Wingate by Wyndham St. Louis/Fenton Route 66

Fenton

Cooper

AED 290

AED 335 total

includes taxes & fees

18 Oct - 19 Oct

A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

A lobby with a reception desk, seating area, and large windows.

A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.

A hotel room with a bed, a desk, a television, a sofa, and a lamp.

8. Pear Tree Inn St. Louis Arnold

Arnold

Lynda

AED 331

AED 382 total

includes taxes & fees

7 Oct - 8 Oct

A modern lobby with a stone fireplace, blue sofas, and potted plants.

A modern building with a stone facade, large windows, and a covered entrance area.

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled deck.

A modern kitchen with a coffee machine, microwave, and refrigerator. There is a dining area with tables and chairs.

9. Comfort Suites St. Louis - Sunset Hills

St. Louis

John

AED 434

AED 504 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a large bed, a desk with a chair, a television, and a waste bin.

A modern kitchen with a sink, dishwasher, and microwave. There is a large mirror above the sink and a countertop with various items. The room has a neutral color scheme and a view of a living area with a couch and a TV.

A snack display area with various packaged snacks and a refrigerated section.

10. Hampton Inn & Suites St. Louis/South I-55

St. Louis

Shannon

AED 389

AED 447 total

includes taxes & fees

18 Oct - 19 Oct

A modern living room with a sofa set, a coffee table, and a TV mounted on the wall.

A hotel room with two beds, a flat-screen TV mounted on the wall, a minibar, and a wooden wardrobe.

A reception area with a wooden wall and a large decorative piece. There are two reception counters and a sign on the wall.

A Marriott Fairfield hotel with a covered entrance, stone facade, and a clear sky.

11. Fairfield Inn & Suites by Marriott St. Louis South

St. Louis

Megan

AED 426

AED 490 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

12. Hyatt Place St. Louis/Chesterfield

Chesterfield

Chelsea

AED 476

AED 552 total

includes taxes & fees

5 Oct - 6 Oct

A hotel named Sonesta ES Suites with a staircase leading to the entrance, surrounded by well-maintained greenery and red flowers.

A hotel room with a living area, kitchenette, and a bed.

A 'check in' sign in front of a building with a landscaped garden and a lamp post.

A compact kitchen with a refrigerator, microwave, stove, and a small dining table with two stools.

13. Sonesta ES Suites St. Louis - Chesterfield

Chesterfield

Dennis

AED 362

AED 420 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

A hotel room with a desk, two beds, a television, a lamp, and a cityscape painting on the wall.

An indoor swimming pool area with a hot tub, a table with chairs, and a sign warning of no lifeguard on duty.

A spacious dining area with multiple tables and chairs, large windows, and ceiling lights.

14. Drury Inn & Suites St. Louis Arnold

Arnold

Bailey

AED 463

AED 535 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a central round table, two sofas, and a chandelier.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

A buffet setup with various food items and a decorative vase of flowers.

15. Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Cassandra

AED 477

AED 554 total

includes taxes & fees

8 Oct - 9 Oct

A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.

A large indoor pool with clear glass walls, a tiled edge, and a seating area with chairs and tables.

A modern lobby with a reception desk, seating area, and a fireplace.

A modern living room with a sectional sofa, a round coffee table, and large windows offering a view of the city.

16. Best Western St. Louis Inn

St. Louis

Harold

AED 291

AED 335 total

includes taxes & fees

8 Oct - 9 Oct

An outdoor patio area with wicker furniture and a central fire feature.

A Courtyard Marriott hotel with a parking lot and a green shuttle service.

A modern hotel lobby with a reception desk, seating area, and a television screen displaying a map.

A modern hotel lobby with a bar area, seating arrangements, and a reception desk.

17. Courtyard by Marriott St. Louis Chesterfield

Chesterfield

Kelly

AED 426

AED 496 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with stainless steel appliances, a central island with stools, and a wine cooler.

A swimming pool with a lifebuoy on the wall, poolside chairs, and a sign with pool rules.

A Hilton Garden Inn with a brick facade, a covered entrance, and landscaped gardens.

A spacious lobby with a seating area, a reception desk, and a kitchen area.

18. Hilton Garden Inn Chesterfield

Chesterfield

Bryan

AED 373

AED 435 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with a built-in grill, seating area, and stone walls.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.

19. Residence Inn by Marriott St. Louis Chesterfield

Chesterfield

Chelsea

AED 694

AED 812 total

includes taxes & fees

9 Oct - 10 Oct

An indoor swimming pool with clear water, a tiled border, and a no diving sign.

A modern kitchen with a central island, bar stools, and a patterned rug.

A snack display with various packaged snacks and a 'Treats' sign above.

A hotel room with a large bed, a desk, a chair, and a lamp.

20. Hampton Inn St. Louis/Chesterfield

Chesterfield

Cynthia

AED 373

AED 433 total

includes taxes & fees

11 Oct - 12 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Murphy Hotel Reviews

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"The staff at this location near Lambert Airport is always amazing. The excellent customer service, enjoyable breakfast, and food selection available at 6:00 make every stay a pleasure. The rooms are neat, clean, and very comfortable. I have relatives in St. Louis, but I’m happy to pay to stay here for the convenience and the wonderful experience. Thanks for making my stay so pleasant! Baron C."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"Very friendly and helpful staff. Good breakfast and clean room."

Ameristar Casino Resort and Spa

10/10 Excellent

"Perfect place to stay, for a fun weekend. The pool was amazing!"

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Todo estubo muy bien y me encanto el hotel estube muy comoda y volveria ir sin duda."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Very friendly staff."

Tru By Hilton St. Louis Downtown

10/10 Excellent

"The hotel was very nice and friendly. I liked everyone in front desk during the morning afternoon evening. They were great. It was good but the ballet sucked. He was very rude and that was at 5 PM on Wednesday, September 30, 2026"

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"It was a great hotel located in a very neat part of town. It was clean and fit our needs perfectly."

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Walking distance to Lambo"

The Cheshire

8/10 Good

"Staff responded quickly to requests."

More cheap stays in Murphy

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

AED 291

AED 335 total

8 Oct - 9 Oct

includes taxes & fees

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

AED 328

AED 384 total

1 Nov - 2 Nov

includes taxes & fees

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

AED 331

AED 389 total

11 Oct - 12 Oct

includes taxes & fees

9.2/10 Wonderful! (3,267 reviews)

The West End

4215 Lindell Blvd St. Louis MO

AED 305

AED 430 total

4 Oct - 5 Oct

includes taxes & fees

8.6/10 Excellent! (662 reviews)

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO

AED 436

AED 501 total

25 Oct - 26 Oct

includes taxes & fees

AC Hotel St. Louis Clayton

227 South Central Ave St. Louis MO

AED 472

AED 551 total

11 Oct - 12 Oct

includes taxes & fees

Frequently asked questions

Where is the best place to stay in Murphy?

Located 14.6 mi (23.5 km) from the heart of Murphy, Clayton Plaza Hotel & Extended Stay is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Pear Tree Inn St. Louis Airport and Renaissance St. Louis Airport Hotel. See all available top hotels, or vacation rentals in Murphy.

What are some of the best vacation home rentals in Murphy?

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!: This vacation home rental near Murphy is located in the city center and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Murphy.

If I need to cancel my hotel reservation in Murphy, will I receive a refund?

Yes! Most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Murphy.

Where can I learn more about changing or cancelling my trip to Murphy?

For additional details about changing or cancelling your trip to Murphy, go to https://www.expedia.com/service/.

What is staying in Murphy like?

Travelers to Murphy will find plenty to explore and enjoy. A top sight in the area is St. Louis Zoo. There are 1863 hotels and other accommodations in the surrounding area. Find out more about Murphy.

What is there to see in Murphy?

A favorite place to visit is Lone Elk Park. Additionally, you'll find St. Louis Zoo in the area. Check out what more to see and do in Expedia's Murphy guide.

What's the seasonal weather like in Murphy?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Murphy is 52 inches.

Find hotels in Murphy, MO from AED 335

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Murphy

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Murphy hotels

1. La Quinta Inn & Suites by Wyndham St Louis Route 66

2. Best Western Plus Fenton

3. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

4. Drury Inn & Suites Southwest St. Louis

5. The Wildwood Hotel

6. Best Western St. Louis-Kirkwood Route 66

7. Wingate by Wyndham St. Louis/Fenton Route 66

8. Pear Tree Inn St. Louis Arnold

9. Comfort Suites St. Louis - Sunset Hills

10. Hampton Inn & Suites St. Louis/South I-55

11. Fairfield Inn & Suites by Marriott St. Louis South

12. Hyatt Place St. Louis/Chesterfield

13. Sonesta ES Suites St. Louis - Chesterfield

14. Drury Inn & Suites St. Louis Arnold

15. Drury Plaza Hotel St. Louis Chesterfield

16. Best Western St. Louis Inn

17. Courtyard by Marriott St. Louis Chesterfield

18. Hilton Garden Inn Chesterfield

19. Residence Inn by Marriott St. Louis Chesterfield

20. Hampton Inn St. Louis/Chesterfield

Top Murphy Hotel Reviews

Drury Inn & Suites St. Louis Airport

Pear Tree Inn St. Louis Near Union Station

Ameristar Casino Resort and Spa

Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Airport

Tru By Hilton St. Louis Downtown

Drury Plaza Hotel St. Louis Union Station

Hollywood Casino & Hotel St. Louis

The Cheshire

More cheap stays in Murphy

Best Western St. Louis Inn

Tru By Hilton St. Louis Downtown

Pear Tree Inn St. Louis Airport

The West End

Hampton Inn St. Charles St. Peters

AC Hotel St. Louis Clayton

Frequently asked questions

Go further with the Expedia app