A sunset over a river with a bridge, surrounded by sparse trees and dry grass.

Murphysboro Vacation Rentals

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Check prices for these dates

In two weeks
27 Nov - 29 Nov
In two months
8 Jan - 10 Jan
In three months
5 Feb - 7 Feb
In four months
5 Mar - 7 Mar

Our top choices for Murphysboro vacation rentals

A serene outdoor setting with a wooden dock leading to a calm pond, surrounded by a grassy area and a few buildings in the background.

1. Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
3.0 star property
Murphysboro
The price is AED 441
AED 863 total
includes taxes & fees
15 Nov - 16 Nov
Pet Friendly! Couples Retreat in Southern Illinois
A hot tub surrounded by trees with autumn foliage.

2. 2BR Private Retreat • Hot Tub • Near SIU & Shawnee Wine Trail

2BR Private Retreat • Hot Tub • Near SIU & Shawnee Wine Trail
Murphysboro
8.8 out of 10, Excellent, (3 reviews)
"The home was clean inside & the host was very welcoming and prompt returning messages & meeting needs. The kitchen was very well stocked but could use a few items added to make our stay a little more comfortable such as a crock pot & blender. Overall this home was a good fit for my mom and I."
United States
Corina S.
The price is AED 358
AED 831 total
includes taxes & fees
1 Dec - 2 Dec
2BR Private Retreat • Hot Tub • Near SIU & Shawnee Wine Trail
A modern kitchen with a dining table, chairs, and a refrigerator.

3. The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.
Murphysboro
9.6 out of 10, Exceptional, (35 reviews)
"We enjoyed our visit"
United States
Tim P.
The price is AED 446
AED 695 total
includes taxes & fees
16 Nov - 17 Nov
The Lab! Come stay in our brand new space.
Property grounds

4. Cabin 2: Lakeside in Murphysboro

Cabin 2: Lakeside in Murphysboro
Murphysboro
8.0 out of 10, Very good, (3 reviews)
"Perfect but beware if you are a sensitive sleeper as the mattress on the queen bed is saggy and in need of replacing. Probably fine for 1 person but 2 people easily roll into the middle making for a not-so-good night's sleep."
United States
Pamela S.
The price is AED 323
AED 861 total
includes taxes & fees
22 Nov - 23 Nov
Cabin 2: Lakeside in Murphysboro
A wooden deck with a barbecue grill and outdoor furniture, surrounded by trees.

5. Fishing Cabin next to Kinkaid Lake

Fishing Cabin next to Kinkaid Lake
Murphysboro
10.0 out of 10, Exceptional, (4 reviews)
"Everything was very clean, parking was easy and plenty of room for the truck and boat. Check in was very easy and great contact with very quick responses. Definitely recommend to stay here."
United States
Dustin M.
The price is AED 624
AED 888 total
includes taxes & fees
14 Nov - 15 Nov
Fishing Cabin next to Kinkaid Lake
A large body of water with wooden buildings on the shore.

6. Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
Murphysboro
8.0 out of 10, Very good, (3 reviews)
"We really enjoyed our stay overall. The location was excellent—quiet, peaceful, and set far enough away from town to avoid traffic, but still close enough to get anywhere quickly. The outdoor space was a big plus, especially for our dogs, who had plenty of room to roam. The beds were also very comfortable, which made for a great night’s sleep. The only downside was the cleanliness. The property was noticeably dusty, and the inside of the refrigerator could have been cleaned more thoroughly. With...
United States
Jim P.
The price is AED 323
AED 861 total
includes taxes & fees
22 Nov - 23 Nov
Pet Friendly! Countryside Couples Stay in Illinois
A modern kitchen with white cabinets, a central island, and a stone fireplace.

7. Minutes from Lake |Fire Pit | Like-New 3BR Retreat

Minutes from Lake |Fire Pit | Like-New 3BR Retreat
Murphysboro
9.8 out of 10, Exceptional, (7 reviews)
"Everything with the house was great. Even the minor issues with the internet and washer going down were handled quick. Beautiful property and very communicative"
United States
Scott M.
The price is AED 643
AED 1,614 total
includes taxes & fees
16 Nov - 17 Nov
Minutes from Lake |Fire Pit | Like-New 3BR Retreat
A room with wooden panel walls, a marble floor, and a wooden bench.

8. Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.
Oraville
10.0 out of 10, Exceptional, (6 reviews)
"Very nice place, will definitely be back."
United States
Greg W.
The price is AED 551
AED 635 total
includes taxes & fees
15 Nov - 16 Nov
Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.
A serene outdoor setting with a wooden dock leading to a calm pond, surrounded by a grassy area and a few buildings in the background.

9. Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
Murphysboro
9.0 out of 10, Wonderful, (8 reviews)
"Easy check in and was very clean and close to everything. "
United States
Stephen
The price is AED 323
AED 837 total
includes taxes & fees
15 Nov - 16 Nov
Pet Friendly! Couples Retreat in Southern Illinois
A large body of water with wooden buildings on the shore.

10. Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
2.5 star property
Murphysboro
The price is AED 463
AED 888 total
includes taxes & fees
22 Nov - 23 Nov
Pet Friendly! Countryside Couples Stay in Illinois
A compact kitchen with a black refrigerator, a microwave, a stove, and a toaster.

11. Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.
Oraville
9.4 out of 10, Exceptional, (3 reviews)
"Great place great communication"
United States
Kevin E.
The price is AED 404
AED 475 total
includes taxes & fees
15 Nov - 16 Nov
Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.
A wooden cabinet with stacked plates and a large black container.

12. Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress
Oraville
9.4 out of 10, Exceptional, (3 reviews)
"Had a nice time. Loved staying in the camper. The host was very prompt when communicating. Would definitely stay again."
United States
Joseph S.
The price is AED 459
AED 537 total
includes taxes & fees
17 Nov - 18 Nov
Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress
A hammock tied to a wooden post, a wooden deck, and a view of a grassy yard with trees.

13. Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
Makanda
9.8 out of 10, Exceptional, (34 reviews)
"Great host, amenities, and location!"
United States
Kevin W.
The price is AED 430
AED 502 total
includes taxes & fees
15 Nov - 16 Nov
Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
A living room with a beige sofa, a matching armchair, and a coffee table. There is a window with curtains, a floor lamp, and a framed picture on the wall.

14. Located in the Luxurious Pine Manor Estates!

Located in the Luxurious Pine Manor Estates!
Carbondale
10.0 out of 10, Exceptional, (3 reviews)
"This is our second stay at Pine Manor, once in one of the larger homes with our extended family and this time in the carriage house. Both stays were perfect. The accommodations are exception quality and the location idea for our days at Southern Illinois University and the area."
United States
adaire p.
The price is AED 547
AED 1,429 total
includes taxes & fees
1 Dec - 2 Dec
Located in the Luxurious Pine Manor Estates!
A stone fireplace with a television mounted above it, a window with blinds, and a view of the outdoors.

15. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (80 reviews)
"Very clean and comfortable stay"
United States
Alison K.
The price is AED 378
AED 678 total
includes taxes & fees
30 Nov - 1 Dec
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Terrace/patio

16. Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful Makanda

Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful Makanda
Makanda
10.0 out of 10, Exceptional, (3 reviews)
"The Host was thoughtful and accommodating. The house had everything we needed and was clean and comfortable. It was a great time and we would definitely stay there again."
United States
Heather H.
The price is AED 397
AED 467 total
includes taxes & fees
16 Nov - 17 Nov
Convenient, Cozy and Pet Friendly 2-bedroom home in Beautiful Makanda
A black barbecue grill with a propane tank on a wooden deck.

17. Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.8 out of 10, Exceptional, (58 reviews)
"We enjoyed our stay at the well outfitted cabin near the Shawnee Wine Trail. Cabin is conveniently located near Giant City State Park and the lodge restaurant. "
United States
Janine B.
The price is AED 441
AED 816 total
includes taxes & fees
16 Nov - 17 Nov
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
An outdoor deck with a table and chairs, surrounded by trees.

18. Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi

Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi
Makanda
9.4 out of 10, Exceptional, (56 reviews)
"Great place to stay and host was wonderful! Definitely would stay again in the future."
United States
Teal B.
The price is AED 378
AED 678 total
includes taxes & fees
23 Nov - 24 Nov
Minutes to Giant City - SIU - Shawnee Winetrail - Shawnee Forest - Wi-Fi
A grassy outdoor area with a fire pit and three Adirondack chairs.

19. The Cozy Corner

The Cozy Corner
De Soto
10.0 out of 10, Exceptional, (3 reviews)
"Extremely clean, beautifully decorated and every amenity a person could possibly need. Great response time."
United States
yvonne o.
The price is AED 422
AED 518 total
includes taxes & fees
15 Nov - 16 Nov
The Cozy Corner
A cabin with a wooden deck and a covered porch.

20. Hot Tub Cabin- In the Heart of Shawnee Wine Trail

Hot Tub Cabin- In the Heart of Shawnee Wine Trail
Carbondale
10.0 out of 10, Exceptional, (5 reviews)
"Loved the cabin and the hot tub. Very relaxing, we will definitely be back."
United States
Jonathan G.
The price is AED 778
AED 1,060 total
includes taxes & fees
15 Nov - 16 Nov
Hot Tub Cabin- In the Heart of Shawnee Wine Trail
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Murphysboro Hotel Reviews

Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

10/10 Excellent
"Room , staff, breakfast, ac heat, bathroom all top notch, no complaints. Enjoyed my stay. THANKS"
Dennis 3-night trip
Posted 6 hours ago
Comfort Inn & Suites Marion I-57

Frequently asked questions

Are there vacation rentals in Murphysboro?

Yes, there are vacation rentals near the most popular points of interest in Murphysboro, or you can select a secluded option if you'd like a relaxing place to stay. Murphysboro is known for its restaurants and golf courses. Make sure you have time to check out the parks and museums during your trip.

What are some of the best vacation rentals in Murphysboro?

* On the Wine Trail * Hot Tub * Wi-Fi *: Visitors like this Murphysboro vacation home rental. It is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

How many vacation rentals are there in Murphysboro?

Choose from 17 Expedia vacation rentals in Murphysboro for a memorable vacation.

What’s there to see and do in Murphysboro?

Shawnee National Forest and Kinkaid Lake are a couple of scenic spots to enjoy the outdoors, whereas General John A. Logan Museum is one of the cultural attractions. Other places in town to visit include Lake Murphysboro State Park and Hickory Ridge Public Golf Center.

What’s a vacation rental in Murphysboro like?

A vacation rental is a private property you can book for short or long periods in Murphysboro. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can offer a sense of safety away from shared hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips.