Panama City Vacations

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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
View of the Panama City Old Town

Casco Viejo

4.5/5(179 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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Panama City Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is AED 520 per night from Jun 2 to Jun 3
AED 520
AED 571 total
2 Jun - 3 Jun
includes taxes & fees
9/10 Wonderful! (5,496 reviews)
"The hotel and location were amazing. I truly enjoy the daily breakfast buffet."

Reviewed on 28 May 2026

Hotel Riu Plaza Panama
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Fully refundable
The price is AED 326 per night from Jun 17 to Jun 18
AED 326
AED 358 total
17 Jun - 18 Jun
includes taxes & fees
9.2/10 Wonderful! (1,116 reviews)
"Todo Estuvo Excelente Muchas Gracias 10/10"

Reviewed on 26 May 2026

The Executive Hotel
Hotel Ojos del Rio

Hotel Ojos del Rio

3.5 out of 5
calle 41 este Panama City Panama
Fully refundableReserve now, pay when you stay
The price is AED 182 per night from May 30 to May 31
AED 182
AED 201 total
30 May - 31 May
includes taxes & fees
8/10 Very Good! (1,001 reviews)
"Me gusto el hotel es muy bonito"

Reviewed on 21 May 2026

Hotel Ojos del Rio
See all 1,683 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How do I find cheap flights to Panama City that have flexible change policies?
By using our clever "No change fee" filter, that's how. Simply type in your travel details, click the "Search" button, then tick the checkbox under the "Flexible change policies" heading (left-hand side of your screen). Expedia makes it a snap to find flexible and affordable airfares to Panama City.
Which airlines fly to Panama City?
Book a seat with one of these airlines and exciting Panama City will be yours to explore:

  • Copa Airlines - 915 flights to or near Panama City each month, including 915 flights to Tocumen Intl. Airport (PTY) per month.
  • United Airlines - 152 flights to or near Panama City each month, including 152 flights to Tocumen Intl. Airport (PTY) per month.
  • American Airlines - 30 flights to or near Panama City each month, including 30 flights to Tocumen Intl. Airport (PTY) per month.

How can I find cheap tickets to Panama City?
You'll always find a terrific deal with Expedia, but our "flexible dates" search function makes it that much easier. Enter your preferred travel date, then click on the flexible dates link above to compare prices for nearby days. was the best price for a flight to Panama City in the last seven days.
How much is a flight to Panama City?
In the last seven days, round-trip airfares to Panama City sold from just and reached a maximum price of . For one-way trips leaving (), the cheapest seat during this same period was .
What are the most popular airports to fly into in Panama City?
Jet into Tocumen Intl. Airport (PTY) and sample the best that Panama City has to offer. As the region's primary entry point, about 1,097 flights touch down here every month.
When is the cheapest time to fly to Panama City?
Take off to Panama City early on in the week and you'll usually be rewarded with more affordable fares. Tuesday is known for being the cheapest day to fly out, with Monday a close second. If you're eager to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Panama City?
In the last seven days, fares to Panama City ranged from to .
What months are the cheapest to book a flight to Panama City?
The ideal month to snare a fabulous deal to Panama City is February, while prices are at a premium in December. Try to avoid this month if you're watching your pennies.
How long is a flight to Panama City?
The time it takes will largely depend on the place you're traveling from. This list of the most popular routes to Panama City will give you an idea of what to expect:

  • Miami, FL (MIA-Miami Intl.) to Tocumen Intl. Airport (PTY) - 3 hours and 13 minutes
  • Orlando, FL (MCO-Orlando Intl.) to Tocumen Intl. Airport (PTY) - 3 hours and 30 minutes
  • Los Angeles, CA (LAX-Los Angeles Intl.) to Tocumen Intl. Airport (PTY) - 6 hours and 23 minutes

What are the best things to do in Panama City?

  • Begin your Panama City vacation in the happening city of Ancon. There's plenty to keep you occupied here, from top attractions like Soberania National Park to spectacular food, shopping, arts and more.
  • When deciding what kind of clothing to bring on your trip, bear in mind that Ancon has a tropical monsoon climate. To give you a better idea of what to expect, check out the weather conditions before you leave.
  • Be sure to make Juan Diaz your next port of call. It's approximately 14 kilometers to the east of Ancon and home to Los Pueblos Commercial Center, one of the destination's best sights.