Photo by Isa

Find 5 Star Hotels in Santa Ana from AED 339

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Santa Ana 5 Star Hotels

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
This weekend
3 Oct - 5 Oct
Next weekend
10 Oct - 12 Oct

Compare Santa Ana 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4332)
"Excellent stay!!"
The price is AED 436
AED 479 total
includes taxes & fees
5 Oct - 6 Oct
Hotel Riu Plaza Panama
Waldorf Astoria Panama
View from property

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1000)
"Great hotel for my recent stay in Panam "
The price is AED 823
AED 905 total
includes taxes & fees
25 Oct - 26 Oct
Waldorf Astoria Panama
JW Marriott Panama
4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities "
The price is AED 809
AED 889 total
includes taxes & fees
17 Oct - 18 Oct
JW Marriott Panama
The Westin Playa Bonita Panama
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1000)
"Excelente hotel. "
The price is AED 546
AED 601 total
includes taxes & fees
13 Oct - 14 Oct
The Westin Playa Bonita Panama
Sofitel Legend Casco Viejo, Panama City
Exterior

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (512)
"Great stay"
The price is AED 1,074
AED 1,182 total
includes taxes & fees
1 Nov - 2 Nov
Sofitel Legend Casco Viejo, Panama City
Renaissance Panama City Hotel
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

5.0 star property
9.0 out of 10, Wonderful, (65)
"The Room was very clean, all staff were very kind and professional, the breakfast and dinner are so delicious, nothing comparative with other restaurant around. "
The price is AED 378
AED 416 total
includes taxes & fees
10 Oct - 11 Oct
Renaissance Panama City Hotel
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (611)
"Staff was lovely - especially front desk, door staff, cleaning team and room service. Only critique is that service was very slow in the restaurant both times but otherwise a lovely visit. "
The price is AED 810
AED 891 total
includes taxes & fees
10 Oct - 11 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
W Panama
2 restaurants, local cuisine

W Panama

5.0 star property
9.0 out of 10, Wonderful, (1001)
"Great hotel "
The price is AED 686
AED 755 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
Bristol Panama, a Registry Collection Hotel
Couples treatment rooms, sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1000)
"We had an amazing time, great hotel and great breakfast. "
The price is AED 450
AED 495 total
includes taxes & fees
23 Oct - 24 Oct
Bristol Panama, a Registry Collection Hotel
Hilton Panama
Outdoor pool

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1000)
"Great property You don’t go wrong Amenities are great Location is perfect area safe and walkable rooms are nice large clean modern "
The price is AED 843
AED 927 total
includes taxes & fees
10 Oct - 11 Oct
Hilton Panama
Megapolis Hotel Panamá
View from property

Megapolis Hotel Panamá

5.0 star property
8.4 out of 10, Very Good, (1000)
"Great stay! Very safe!"
Megapolis Hotel Panamá
Waymore Hotel Spa and Casino
Outdoor pool

Waymore Hotel Spa and Casino

5.0 star property
6.2 out of 10, (1000)
"Clean and safe. Lot of security."
Waymore Hotel Spa and Casino
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Ana.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is AED 433 per night from Nov 1 to Nov 2
AED 433
AED 477 total
1 Nov - 2 Nov
includes taxes & fees
8.4/10 Very Good! (2,260 reviews)
Still don't see what you're looking for?
See all properties in Santa Ana.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Ana Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"It was our first time at this hotel, everything was to our satisfaction."
Jean 5-night trip
Posted 23 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

What are the best 5-star hotels in Santa Ana?
According to reviews by our customers, Villa Palma Boutique Hotel is one of the best properties for an indulgent stay in the Panama City neighborhood of Santa Ana. Want more 5-star hotels around the area? Waldorf Astoria Panama and Hilton Panama will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Ana?
The amount you pay for a 5-star hotel in Santa Ana can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best deal on a high-end getaway.

  • Search for the lowest price per night from AED 339

What makes a hotel 5 stars in Santa Ana?
From high-end dining venues and 24-hour fitness centers to swimming pools and premium bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it requires more than just upscale conveniences to receive a 5-star rating. Hotels must also offer superior guest services like in-room massages, laundry and dry cleaning and room service any time day or night.

Explore a world of travel with Expedia

Explore a world of travel with Expedia