Find Business Hotels in Santa Ana
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Santa Ana Business Hotels
Our top choices for Santa Ana business-friendly hotels
Crowne Plaza Panama Airport by IHG
Tocumen
8.4 out of 10, Very Good, (2309)
"The room was clean and the staff were nice! "
CECILIA
The price is AED 404
AED 444 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Riu Plaza Panama
Bella Vista
9.0 out of 10, Wonderful, (4640)
"Awesome great place to stay "
Herbert
The price is AED 450
AED 495 total
includes taxes & fees
10 Dec - 11 Dec
Riande Aeropuerto Hotel & Casino
Tocumen
8.6 out of 10, Excellent, (1858)
"Very nice hotel centered around courtyard and pool. Convenient for airport "
Miles
The price is AED 459
AED 505 total
includes taxes & fees
13 Dec - 14 Dec
Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
9.6 out of 10, Exceptional, (1103)
"Property and location was excellent.
Staff is very accommodating and helpful. "
Helen
The price is AED 437
AED 481 total
includes taxes & fees
24 Dec - 25 Dec
Courtyard by Marriott Panama Metromall
Cerro Viento
8.8 out of 10, Excellent, (1005)
"Conveniently located near the airport and major shopping outlets."
Greg
The price is AED 372
AED 409 total
includes taxes & fees
5 Jan - 6 January 2026
Megapolis Hotel Panamá
San Francisco
8.4 out of 10, Very Good, (1261)
"Clean rooms, staff was amazing!!"
Christopher
The price is AED 481
AED 530 total
includes taxes & fees
22 Dec - 23 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
9.6 out of 10, Exceptional, (636)
"As usual the stay was amazing in this hotel"
Jose
The price is AED 851
AED 936 total
includes taxes & fees
12 Dec - 13 Dec
Radisson Hotel Panama Canal
Amador
8.6 out of 10, Excellent, (1002)
"Wonderful staff and easy checkin!"
Kristin
The price is AED 256
AED 282 total
includes taxes & fees
22 Dec - 23 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Santa Ana Hotel Reviews
Novotel Panama City
10/10 Excellent
Explore a world of travel with Expedia
Hotels near popular Panama City Attractions
- Hotels near Avenida Central
- Hotels near Albrook Shopping Mall
- Hotels near Multiplaza Pacific Mall
- Hotels near Cinta Costera
- Hotels near Amador Causeway
- Hotels near Avenida Balboa
- Hotels near Via Espana
- Hotels near Gamboa Rainforest Resort
- Hotels near El Dorado Mall
- Hotels near Fuerte Amador Resort & Marina
Santa Ana Hotels by Star Rating
Explore more hotels
- The Westin Playa Bonita Panama
- W Panama
- Sheraton Grand Panama
- Decapolis Hotel Panama City
- JW Marriott Panama
- Novotel Panama City
- The Executive Hotel
- Hyatt Regency Panama City
- Riande Urban Hotel
- Waymore Hotel Spa & Casino
- AC Hotel by Marriott Panama City
- Central Hotel Panama Casco Viejo
- Ramada Plaza by Wyndham Panama Punta Pacifica
- Courtyard by Marriott Panama Metromall
- Aloft Panama
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- Arcadia Condo Suites
- Sofitel Legend Casco Viejo, Panama City
- Residence Inn by Marriott Panama City
- MARINN Tropical Vibes Hotel