Find Business Hotels in San Francisco
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on San Francisco Business Hotels
Top San Francisco Business Hotels
Plaza Paitilla Inn Hotel
San Francisco
9.4 out of 10, Exceptional, (2135)
"Great location, friendly staff, excellent views and the best breakfast around."
Gregory
The price is AED 431
AED 475 total
includes taxes & fees
30 Dec - 31 Dec
Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
9.6 out of 10, Exceptional, (1103)
"Property and location was excellent.
Staff is very accommodating and helpful. "
Helen
The price is AED 437
AED 481 total
includes taxes & fees
24 Dec - 25 Dec
Megapolis Hotel Panamá
San Francisco
8.4 out of 10, Very Good, (1259)
"Clean rooms, staff was amazing!!"
Christopher
The price is AED 508
AED 559 total
includes taxes & fees
3 Jan - 4 January 2026
JW Marriott Panama
San Francisco
9.0 out of 10, Wonderful, (1006)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
Sarran
The price is AED 889
AED 978 total
includes taxes & fees
4 Jan - 5 January 2026
Las Americas Golden Tower Panama
San Francisco
9.0 out of 10, Wonderful, (1003)
"Wonderful stay!"
Martha
The price is AED 578
AED 642 total
includes taxes & fees
19 Dec - 20 Dec
Decapolis Hotel Panama City
San Francisco
8.6 out of 10, Excellent, (1435)
"Excellent stay. Wonderful staff, good location and excellent breakfast"
Michael
The price is AED 411
AED 452 total
includes taxes & fees
10 Dec - 11 Dec
Courtyard by Marriott Panama Multiplaza Mall
San Francisco
8.8 out of 10, Excellent, (1002)
"Perfect stay "
pedro
The price is AED 403
AED 443 total
includes taxes & fees
3 Jan - 4 January 2026
Sheraton Grand Panama
San Francisco
8.6 out of 10, Excellent, (988)
"Was amazing food was delicious and stay was great "
Amanda
The price is AED 496
AED 545 total
includes taxes & fees
14 Dec - 15 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top San Francisco Hotel Reviews
Plaza Paitilla Inn Hotel
10/10 Excellent
Explore a world of travel with Expedia
More Hotel Options in San Francisco
- Adults Only Resorts & Hotels in San Francisco
- Adventure Hotels in San Francisco
- Beach Hotels in San Francisco
- Casinos in San Francisco
- Family Hotels in San Francisco
- Historic Hotels in San Francisco
- Hotel with a Concierge in San Francisco
- Hotels with Bars in San Francisco
- Hotels with Free Parking in San Francisco
- Hotels with WiFi in San Francisco
- Hotels with a Pool in San Francisco
- Hotels with smoking rooms in San Francisco
- Pet-friendly Hotels in San Francisco
- Resorts & Hotels with Spas in San Francisco
- Shopping Hotels in San Francisco
Hotels near popular Panama City Attractions
- Hotels near Multiplaza Pacific Mall
- Hotels near Avenida Balboa
- Hotels near ATLAPA Conventions Center
- Hotels near Multicentro Panama
- Hotels near Pacific Center
- Hotels near Panama Canal Murals
- Hotels near Hospital Punta Pacífica
- Hotels near Omar Torrijos Recreational Park
- Hotels near Colonial Religious Art Museum
- Hotels near Albrook Shopping Mall
San Francisco Hotels by Star Rating
Explore more hotels
- San Francisco by Wynwood House
- Hotel Riu Plaza Panama
- Crowne Plaza Panama Airport by IHG
- Waldorf Astoria Panama
- Marriott Panama Hotel
- Dreams Playa Bonita Panama - All Inclusive
- Principe Hotel and Suites
- The Westin Playa Bonita Panama
- W Panama
- Novotel Panama City
- The Executive Hotel
- Hyatt Regency Panama City
- Riande Urban Hotel
- Waymore Hotel Spa & Casino
- AC Hotel by Marriott Panama City
- Central Hotel Panama Casco Viejo
- Courtyard by Marriott Panama Metromall
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- Arcadia Condo Suites
- Sofitel Legend Casco Viejo, Panama City