Find 4 Star Hotels in San Francisco from AED 179

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Check availability on San Francisco 4 Star Hotels

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Compare San Francisco 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4.0 star property
Tocumen
8.4 out of 10, Very Good, (2293)
"The room was clean and the staff were nice! "
United States
CECILIA
The price is AED 404
AED 444 total
includes taxes & fees
23 Dec - 24 Dec
Crowne Plaza Panama Airport by IHG
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very Good, (1252)
"Its a very beautiful hotel with view and very good breakfast "
United States
Patrick
The price is AED 449
AED 494 total
includes taxes & fees
19 Dec - 20 Dec
Megapolis Hotel Panamá
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1001)
"Wonderful stay!"
United States
Martha
The price is AED 583
AED 647 total
includes taxes & fees
14 Dec - 15 Dec
Las Americas Golden Tower Panama
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

4.0 star property
Panama City
9.0 out of 10, Wonderful, (1000)
"Great breakfast "
United States
Amina
The price is AED 521
AED 573 total
includes taxes & fees
12 Dec - 13 Dec
Marriott Panama Hotel
Front of property
Novotel Panama City

Novotel Panama City

4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1010)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is AED 360
AED 396 total
includes taxes & fees
9 Dec - 10 Dec
Novotel Panama City
Restaurant
Studio Coliving

Studio Coliving

4.5 star property
Bella Vista
7.8 out of 10, Good, (575)
"The staff was friendly and always helpful when I had requests. The room was"
United States
Toni-Q
The price is AED 162
AED 179 total
includes taxes & fees
7 Dec - 8 Dec
Studio Coliving
Exterior
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4.0 star property
San Francisco
8.6 out of 10, Excellent, (1430)
"Excellent stay. Wonderful staff, good location and excellent breakfast"
United States
Michael
The price is AED 280
AED 308 total
includes taxes & fees
14 Dec - 15 Dec
Decapolis Hotel Panama City
Outdoor pool, pool umbrellas, sun loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1099)
"Property and location was excellent. Staff is very accommodating and helpful. "
Canada
Helen
The price is AED 446
AED 491 total
includes taxes & fees
4 Jan - 5 January 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Front of property - evening/night
American Trade Hotel

American Trade Hotel

4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (600)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is AED 1,071
AED 1,178 total
includes taxes & fees
4 Jan - 5 January 2026
American Trade Hotel
Terrace/patio
Sheraton Grand Panama

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (988)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is AED 496
AED 545 total
includes taxes & fees
13 Dec - 14 Dec
Sheraton Grand Panama
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (611)
"Friwndly staff, clean rooms and a very convenient location."
United States
Alisa
The price is AED 267
AED 397 total
includes taxes & fees
7 Dec - 8 Dec
Waymore Hotel Spa & Casino
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1002)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is AED 387
AED 426 total
includes taxes & fees
5 Jan - 6 January 2026
Courtyard by Marriott Panama Metromall
Exterior
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

4.0 star property
Bella Vista
8.8 out of 10, Excellent, (1003)
"The staff members are amazing!!"
United States
Cherisse
The price is AED 286
AED 335 total
includes taxes & fees
9 Dec - 10 Dec
Holiday Inn Panama Distrito Financiero by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1002)
"Great staff, perfect location, and delicious breakfast. "
United States
Tatiana
The price is AED 742
AED 816 total
includes taxes & fees
12 Dec - 13 Dec
Central Hotel Panama Casco Viejo
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco
8.8 out of 10, Excellent, (1001)
"Perfect stay "
United States
pedro
The price is AED 434
AED 477 total
includes taxes & fees
3 Jan - 4 January 2026
Courtyard by Marriott Panama Multiplaza Mall
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (534)
"Amazing hotel amazing view service great location perfect "
United States
Melissa
The price is AED 528
AED 580 total
includes taxes & fees
3 Jan - 4 January 2026
Residence Inn by Marriott Panama City
Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (118)
"Great hotel fair price"
United States
Santiago
The price is AED 496
AED 545 total
includes taxes & fees
13 Dec - 14 Dec
Hyatt Regency Panama City
Front of property
Hotel San Felipe

Hotel San Felipe

4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (243)
"Really nice staff and property is in amazing location "
United States
Michael
The price is AED 446
AED 491 total
includes taxes & fees
9 Dec - 10 Dec
Hotel San Felipe
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is AED 1,183
AED 1,302 total
includes taxes & fees
23 Dec - 24 Dec
Hotel La Compañía Casco Antiguo
2 outdoor pools, pool umbrellas, sun loungers
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 star property
Amador
8.6 out of 10, Excellent, (1001)
"Wonderful staff and easy checkin!"
United States
Kristin
The price is AED 256
AED 282 total
includes taxes & fees
23 Dec - 24 Dec
Radisson Hotel Panama Canal
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in San Francisco.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
The price is AED 420 per night from Dec 9 to Dec 10
AED 420
AED 462 total
9 Dec - 10 Dec
includes taxes & fees
9/10 Wonderful! (4,620 reviews)
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PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top San Francisco Hotel Reviews

Sheraton Grand Panama

Sheraton Grand Panama

10/10 Excellent
"Was amazing food was delicious and stay was great "
Amanda 5-night trip
Posted 3 days ago
Sheraton Grand Panama

Frequently asked questions

What are the best 4-star hotels in San Francisco?
Ramada Plaza By Wyndham Panama Punta Pacífica is among our travelers' favorite 4-star hotels around San Francisco. A Champagne service and private picnic options are only the start of its many conveniences. Another property that receives top reviews for its unforgettable guest experience is Sheraton Grand Panama. Book your stay here and enjoy access to beauty services and premium bedding.
How much does it cost to stay in a 4-star hotel in San Francisco?
To find a 4-star hotel in San Francisco that fits your budget, make use of Expedia's handy filter tool. Check out the availability during your vacation dates and use our pricing filter to set your limit. You can also list your results by the most economical stay first.

  • Search for the lowest price from AED 462

What's the difference between 5-star and 4-star hotels in San Francisco?
Treat yourself to luxury during your San Francisco getaway by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are usually packed with amenities like complimentary bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and memorable one. Concierge assistance, elegant furnishings and gourmet dining are a few of the superior services and conveniences you'll likely have access to.

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