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Check prices for these dates

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

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Our top choices for Santa Cruz hotels

A building with a pool, outdoor seating, and a hot tub.
An outdoor dining area with tables and chairs, string lights, and a covered section.
A multi-story building with multiple windows, a staircase, and a paved entrance area.
A well-maintained grassy lawn with a few trees and a building in the background.

1. Hotel Finca Las Hortensias

Hotel Finca Las Hortensias
Tepotzotlán
United States
Raymond
AED 202
AED 242 total
includes taxes & fees
5 Nov - 6 Nov
Hotel Finca Las Hortensias
A rooftop spa with two massage tables, a hot tub, and a seating area.
A rooftop lounge area with wooden loungers, beige cushions, and a wooden table.
A dining table with plates of food, wine glasses, and cutlery.
A stone entrance with a lit frame, a sign reading "La Morada Boutique Hotel & Spa", and a palm tree in the background.

2. La Morada Tepotzotlan Boutique & Spa

La Morada Tepotzotlan Boutique & Spa
Tepotzotlán
Mexico
Karina Ponce
AED 737
AED 896 total
includes taxes & fees
7 Oct - 8 Oct
La Morada Tepotzotlan Boutique & Spa
A spacious lobby with a reception desk, seating area, and large windows.
A hotel with a sign reading 'City Express by Marriott,' palm trees, and a van parked in front.
A hotel room with two beds, a desk, a chair, a wardrobe, and a window with a view.
An outdoor patio with tables and chairs, a large umbrella, and a potted plant.

3. City Express by Marriott Tepotzotlan

City Express by Marriott Tepotzotlan
Tepotzotlán
Mexico
Silvia
AED 255
AED 306 total
includes taxes & fees
6 Nov - 7 Nov
City Express by Marriott Tepotzotlan
A modern lobby with large windows, a sofa, ottomans, and a coffee table.
A gym with treadmills, elliptical machines, and a mirror wall.
A modern dining area with a large window, wooden tables, and hanging pendant lights.
A hotel room with two beds, a desk, a chair, a TV, and a mirror.

4. Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham

Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham
Cuautitlan Izcalli
United States
LEONARDO
AED 252
AED 303 total
includes taxes & fees
11 Oct - 12 Oct
Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham
A modern hotel reception area with a white reception desk, a digital screen displaying the weather, and a green sofa.
A modern living room with a dining table, sofa, TV, and kitchen area.
A hotel room with two beds, a headboard, and a curtain.
A conference room with rows of chairs, a projector screen, and blue walls.

5. Fiesta Inn Express Perinorte

Fiesta Inn Express Perinorte
Tultitlan
United States
Mario
AED 297
AED 356 total
includes taxes & fees
9 Oct - 10 Oct
Fiesta Inn Express Perinorte
A reception area with a blue wall, a reception desk, and two chairs.
A modern living room with a large flat-screen TV, wooden shelving, a beige sofa, and a glass partition wall.
A modern dining area with white tables and blue chairs, a large black pillar, and a wall-mounted TV.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view of trees.

6. One Cuautitlan

One Cuautitlan
Cuautitlan Izcalli
United States
Luis Alberto
AED 270
AED 329 total
includes taxes & fees
6 Nov - 7 Nov
One Cuautitlan
A pool area with lounge chairs and umbrellas, a tiled pool, and a modern building in the background.
A modern bar area with a red and white color scheme, featuring a menu board, multiple shelves with bottles, and bar stools.
A modern office space with multiple desks, computers, and chairs.
A hotel room with two beds, a desk with a computer, and a TV.

7. Fiesta Inn Cuautitlan

Fiesta Inn Cuautitlan
Cuautitlan Izcalli
United States
Bruno
AED 321
AED 388 total
includes taxes & fees
17 Oct - 18 Oct
Fiesta Inn Cuautitlan
An outdoor patio with string lights, wooden tables, and chairs.
A buffet setup with multiple food stations, overhead lighting, and a red counter.
A modern hotel building with a checkered facade, multiple balconies, and a prominent 'ibis' sign.
A dog in a yellow jacket walking on a concrete path surrounded by greenery and buildings.

8. ibis Mexico Perinorte

ibis Mexico Perinorte
Cuautitlan Izcalli
Mexico
J Jesus
AED 164
AED 197 total
includes taxes & fees
23 Oct - 24 Oct
ibis Mexico Perinorte
An indoor swimming pool with lounge chairs and a table, surrounded by white walls and blue ceiling accents.
An ornate wooden door, a stained glass window, and a painting on the wall.
A bar area with a large jar of iced tea, glasses on a tray, and a sign with 'There is Beauty Everywhere'.
A hotel room with two beds, a window, a bedside table, and a wall-mounted lamp.

9. Ramada by Wyndham CDMX Perinorte

Ramada by Wyndham CDMX Perinorte
Tlalnepantla de Baz
United States
Garrett
AED 237
AED 284 total
includes taxes & fees
7 Oct - 8 Oct
Ramada by Wyndham CDMX Perinorte
A modern dining area with a high ceiling, large windows, and a view of the city.
A modern dining area with a high ceiling, large windows, and a view of a cityscape.
A modern hotel building with a flat facade and multiple windows.
A modern office space with a round table, chairs, a sofa, and a view of the city through large windows.

10. City Express Plus by Marriott Ciudad de México Mundo E

City Express Plus by Marriott Ciudad de México Mundo E
Jardines de Santa Monica
Canada
Veronica Esther
AED 258
AED 309 total
includes taxes & fees
18 Oct - 19 Oct
City Express Plus by Marriott Ciudad de México Mundo E
A hotel entrance with a modern design, featuring a glass facade, a central staircase, and a Christmas tree.
A hotel room with a bed, a chair, and a table. There are two lamps on the table.
A hotel room with a wooden door, a bed with a headboard, and a small potted plant in the background.
A hotel reception area with a reception desk, chairs, a vase with flowers, a wall-mounted TV, and a reception sign.

11. Antigua Hotel Boutique

Antigua Hotel Boutique
Ciudad López Mateos
United States
George
AED 270
AED 324 total
includes taxes & fees
11 Oct - 12 Oct
Antigua Hotel Boutique
A hotel entrance with a curved awning, a fountain, and a well-lit building facade.
A Starbucks coffee shop with a menu board, a beverage display, and a refrigerated section.
A buffet with various food items and beverages, set against a brick wall.
A spacious lobby with a grand piano, a reception desk, and wooden doors.

12. Real Inn Perinorte

Real Inn Perinorte
Tlalnepantla de Baz
United States
Jose
AED 264
AED 317 total
includes taxes & fees
19 Oct - 20 Oct
Real Inn Perinorte
A bar area with red and black furniture, a bar counter, and a television screen.
A hotel lobby with a staircase leading to a second floor, a reception desk, and a seating area.
A hotel with a prominent "HOTEL" sign, multiple flags, and a well-lit entrance.
A restaurant with wooden tables and chairs, large windows, and a modern ceiling design.

13. Hotel Parque Satelite

Hotel Parque Satelite
San Lucas Tepetlacalco
Mexico
Yair
AED 150
AED 180 total
includes taxes & fees
7 Oct - 8 Oct
Hotel Parque Satelite
An outdoor dining area with tables and chairs, a view of a cityscape, and a decorative ceiling.
A table set with plates of food, wine glasses, and a glass of juice, surrounded by chairs.
A Holiday Inn Express hotel with a modern design, located near a body of water with a fountain.
A modern bar area with marble countertops, black chairs, and a wooden wine rack.

14. Holiday Inn Express Mexico City Satelite by IHG

Holiday Inn Express Mexico City Satelite by IHG
Ciudad Satélite
United States
Frank
AED 259
AED 311 total
includes taxes & fees
6 Nov - 7 Nov
Holiday Inn Express Mexico City Satelite by IHG
A spacious lobby with modern lighting, a reception desk, seating area, and large windows.
A buffet counter with various food items, a coffee machine, and a microwave.
A hotel building with a sign reading "cityexpress hotels" and multiple illuminated windows.
A modern hotel room with a sofa, a bed with a red blanket, a desk with a chair, and a large window offering a city view.

15. City Express by Marriott Ciudad de México Tlalnepantla

City Express by Marriott Ciudad de México Tlalnepantla
Ciudad Satélite
United States
Juan Manuel
AED 174
AED 209 total
includes taxes & fees
6 Nov - 7 Nov
City Express by Marriott Ciudad de México Tlalnepantla
A hotel room with a large bed, a seating area with a table and chairs, a TV mounted on the wall, and a view of the city through the window.
A gym with multiple cardio machines, including treadmills and stationary bikes, arranged in rows.
A conference room with a long table, chairs, and a projector screen.
A corridor with a long, straight path, a wall-mounted lamp, and a framed picture on the wall.

16. Fiesta Americana México Satélite

Fiesta Americana México Satélite
Tlalnepantla de Baz
United States
Alfonso
AED 496
AED 595 total
includes taxes & fees
18 Oct - 19 Oct
Fiesta Americana México Satélite
A spacious living area with leather sofas, a coffee table, and a large plant.
A gym with treadmills, a weight machine, and a mirror.
A conference room with a long table, white chairs, a painting on the wall, and a projector screen.
A hotel room with a bed, a desk, a chair, a television, and a mirror.

17. Mandarin Carton

Mandarin Carton
Ciudad Satélite
United States
Selena
AED 212
AED 255 total
includes taxes & fees
14 Oct - 15 Oct
Mandarin Carton
A modern lobby with a glass staircase, seating area, and a reception desk.
A buffet with various pastries, desserts, and a vase of flowers.
A hotel room with a large bed, a desk with a chair, a flat-screen TV, and a window with curtains.
A modern interior with a staircase, seating area, and a sign reading "VALLE D'ORADO".

18. NH Mexico City Valle Dorado

NH Mexico City Valle Dorado
Valle Dorado
United States
Alfredo
AED 270
AED 324 total
includes taxes & fees
6 Nov - 7 Nov
NH Mexico City Valle Dorado
A modern kitchen with a large island, bar seating, and a view of the city.
A modern restaurant with a geometric patterned wall, wooden ceiling, and a bar area with stools.
A modern hotel lobby with a reception desk, a refrigerator stocked with beverages, a print station, and a wooden wall with a sign that reads "Connect & Print".
A modern hotel with a prominent 'VIA' sign, a glass facade, and a mix of orange and white buildings.

19. Fairfield Inn & Suites Mexico City Vallejo

Fairfield Inn & Suites Mexico City Vallejo
Azcapotzalco
United States
Karen
AED 340
AED 407 total
includes taxes & fees
19 Oct - 20 Oct
Fairfield Inn & Suites Mexico City Vallejo
A courtyard with white outdoor furniture, large umbrellas, and a building in the background.
A modern hotel with a swimming pool, outdoor seating, and a covered patio area.
A hotel room with two beds, a desk, a chair, a dresser, and a TV on the wall.
A buffet with various desserts and beverages.

20. Krystal Satélite María Bárbara

Krystal Satélite María Bárbara
San Lucas Tepetlacalco
United States
Miguel
AED 182
AED 226 total
includes taxes & fees
1 Nov - 2 Nov
Krystal Satélite María Bárbara
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Top Santa Cruz Hotel Reviews

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

10/10 Excellent
"The staff the back the desk and the people with the black tuxedo needed more experience and friendly, don’t helped and all time have angry face, the rest people nice friendly"
Eduardo 1-night trip
Posted 5 hours ago
Holiday Inn Express Mexico Basilica by IHG
InterContinental Presidente Mexico City by IHG

InterContinental Presidente Mexico City by IHG

10/10 Excellent
"Great Hotel..."
Daniel 4-night trip
Posted 8 hours ago
InterContinental Presidente Mexico City by IHG
Exe Alameda Reforma

Exe Alameda Reforma

10/10 Excellent
"Es un hotel muy atento"
Guadalupe 4-night trip
Posted 1 day ago
Exe Alameda Reforma
Hyatt Regency Mexico City

Hyatt Regency Mexico City

10/10 Excellent
"Excellent overall! Great location!"
Frank 2-night trip
Posted 1 day ago
Hyatt Regency Mexico City
Collections by ULIV Palacio

Collections by ULIV Palacio

10/10 Excellent
"Very very happy with their service"
Leonor 4-night trip
Posted 2 days ago
Collections by ULIV Palacio
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

10/10 Excellent
"All amenities are brand new and modern. Staff is friendly and customer oriented. Lighting, restrooms shower, all very modern and extraordinarily clean. I liked the terrace for dinning and viewing the airport, food is traditionally Mexican and with a delicious taste. Just 2 minute drive by shuttle to the airport, and it is free, working 24/7, this is a plus. Highly recommend it!"
Rodolfo 1-night trip
Posted 4 days ago
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
Collections by ULIV Polanco

Collections by ULIV Polanco

10/10 Excellent
"Excelente lugar 10/10"
PAOLA 1-night trip
Posted 4 days ago
Collections by ULIV Polanco
Hotel MX lagunilla CDMX, Trademark Collection by Wyndham

Hotel MX lagunilla CDMX, Trademark Collection by Wyndham

10/10 Excellent
"It’s very neat and clean"
Jonatan 2-night trip
Posted 4 days ago
Hotel MX lagunilla CDMX, Trademark Collection by Wyndham
Hotel MX forum buenavista CDMX, Trademark by Wyndham

Hotel MX forum buenavista CDMX, Trademark by Wyndham

10/10 Excellent
"Everything was great! The complimentary breakfast was good"
Mauricio 3-night trip
Posted 8 days ago
Hotel MX forum buenavista CDMX, Trademark by Wyndham

More cheap stays in Santa Cruz

Capital Hostal

Capital Hostal

Segunda Cda. de la Séptima del Nogal 18 Mexico City CDMX
AED 50
AED 59 total
3 Nov - 4 Nov
includes taxes & fees
Capital Hostal
Hotel Ancona - Adults Only

Hotel Ancona - Adults Only

226 Calle Eligio Ancona Mexico City CDMX
AED 64
AED 76 total
7 Oct - 8 Oct
includes taxes & fees
Hotel Ancona - Adults Only
Hotel SR92 Only Adults

Hotel SR92 Only Adults

Calle de Francisco Díaz Covarrubias 92 Mexico City CDMX
AED 113
AED 135 total
7 Oct - 8 Oct
includes taxes & fees
7.4/10 Good! (363 reviews)
Hotel SR92 Only Adults
Hostal Casa MX Alameda - Hostel

Hostal Casa MX Alameda - Hostel

Soto 72, Colonia Guerrero Mexico City
AED 199
AED 238 total
7 Oct - 8 Oct
includes taxes & fees
7.8/10 Good! (196 reviews)
Hostal Casa MX Alameda - Hostel
Casa Olea

Casa Olea

C. de Francisco Díaz Covarrubias Mexico City CDMX
AED 214
AED 256 total
20 Oct - 21 Oct
includes taxes & fees
Casa Olea
KALI La Raza Mexico City

KALI La Raza Mexico City

AV. INSURGENTES NORTE 734 Mexico City CDMX
AED 220
AED 263 total
7 Oct - 8 Oct
includes taxes & fees
9.4/10 Exceptional! (411 reviews)
KALI La Raza Mexico City

Frequently asked questions

Where is the best place for a stay in Santa Cruz?
Located 18.9 mi (30.4 km) from the heart of Santa Cruz, Hyatt Regency Mexico City is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Downtown Treasure Place and InterContinental Presidente Mexico City by IHG. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Luxe Polanco Home Private Yard and Private Patio: This vacation home rental outside of Santa Cruz offers a garden, a selection of games, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about changing or cancelling your trip to Santa Cruz, head over to our customer service page.
What is staying in Santa Cruz like?
Those traveling to Santa Cruz are sure to enjoy the sights to see and things to do. In Santa Cruz, there are 2 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Places to visit in the wider area include Hacienda La Concepcion, National Museum of the Viceroyalty, and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually April and May with an average temp of 64°F, while the coldest months are January and December with an average of 57°F. The rainiest months in Santa Cruz are August, July, September, and June, with each month seeing an average of 7 inches of rainfall.