The Best Hotels Closest to Sikeston Depot Museum in Sikeston for 2026

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Our top choices for Sikeston Depot Museum hotels

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

1. Fairfield Inn & Suites by Marriott Sikeston

2.4 km from Sikeston Depot Museum

Roslyn

AED 459 total

includes taxes & fees

19 Nov - 20 Nov

2. TownePlace Suites by Marriott Sikeston

2.3 km from Sikeston Depot Museum

Mark

AED 455 total

includes taxes & fees

19 Nov - 20 Nov

A buffet with various food items, including omelets and baked goods, served in metal containers.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

2.1 km from Sikeston Depot Museum

George

AED 397 total

includes taxes & fees

13 Dec - 14 Dec

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

4. Drury Inn & Suites Sikeston, MO

5.1 km from Sikeston Depot Museum

Tiffany

AED 397 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

5. Best Western Plus Sikeston I-55

5.4 km from Sikeston Depot Museum

Shelley

AED 294 total

includes taxes & fees

14 Dec - 15 Dec

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

6. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

5 km from Sikeston Depot Museum

Craig

AED 282 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

7. Comfort Inn & Suites Sikeston I-55

4.9 km from Sikeston Depot Museum

Fred

AED 352 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

8. Days Inn and Suites by Wyndham Sikeston

5.4 km from Sikeston Depot Museum

Earl

AED 278 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

9. Super 8 by Wyndham Sikeston/Miner Area

4.7 km from Sikeston Depot Museum

Laura

AED 243 total

includes taxes & fees

19 Nov - 20 Nov

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

10. Country Yard Inn and Suite

5.5 km from Sikeston Depot Museum

Marianne

AED 248 total

includes taxes & fees

14 Nov - 15 Nov

View all properties

Compare popular hotels close to Sikeston Depot Museum

Property	Property class	Guest rating
Fairfield Inn & Suites by Marriott Sikeston	3.0 star property	9.4 Exceptional 118 reviews	View
TownePlace Suites by Marriott Sikeston	3.0 star property	9.2 Wonderful 32 reviews	View
Holiday Inn Express & Suites Sikeston Southwest by IHG	2.5 star property	8.8 Excellent 526 reviews	View
Drury Inn & Suites Sikeston, MO	3.0 star property	9.6 Exceptional 1,002 reviews	View
Best Western Plus Sikeston I-55	2.5 star property	8.4 Very good 1,009 reviews	View

Other attractions near Sikeston Depot Museum

Central Park

7.2/10 (56 reviews)

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

See properties

Top Sikeston Depot Museum Hotel Reviews

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

Hampton Inn Sikeston

Sikeston

10/10 Excellent

Stacey

Drury Inn & Suites Sikeston, MO

Sikeston

10/10 Excellent

Judy

Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

10/10 Excellent

Anonymous traveler

Best Western Plus Sikeston I-55

Sikeston

10/10 Excellent

Anonymous traveler

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

10/10 Excellent

Anonymous traveler

Comfort Inn & Suites Sikeston I-55

Sikeston

10/10 Excellent

This is a fantastic hotel! The staff is very wonderful and helpful and thoughtful when my father passed away in November of 2017, part of my family stayed at this hotel. Now I am back here waiting for my mother to arrive for we are going to finally get to see my father who was a Vietnam veteran and was buried at the Bloomfield Cemetery has his headstone put up anyhow I have had some difficulties with a lot of the hotels around here in this one is by far the best I would recommend it to anyone.

Anonymous traveler

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

10/10 Excellent

JACK OR JULIE

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

10/10 Excellent

Britney

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

10/10 Excellent

Kristin

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

Drury Inn & Suites Cape Girardeau

Cape Girardeau

10/10 Excellent

StephM

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

Pear Tree Inn Cape Girardeau West

Cape Girardeau

10/10 Excellent

Kimberly

Frequently Asked Questions

What's the area like around Sikeston Depot Museum?

Sikeston Depot Museum is located in a welcoming area of Sikeston known for its array of dining options. If you're looking for a convenient place to stay, check out the 5 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Sikeston Depot Museum?

Drury Inn & Suites Sikeston, MO is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located 3.2 mi (5.1 km) from Sikeston Depot Museum. Other good choices within 5 miles include Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston.

How many hotels should I expect to find close to Sikeston Depot Museum?

Expedia has 5 hotels and other accommodations within a mile from Sikeston Depot Museum.

If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Sikeston Depot Museum.

Where can I learn more about changing or cancelling my trip in the area near Sikeston Depot Museum?

To find more details about picking new dates or cancelling your stay near Sikeston Depot Museum, head over to our customer service page.

Find hotels near Sikeston Depot Museum, Sikeston from AED 208

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Our top choices for Sikeston Depot Museum hotels

1. Fairfield Inn & Suites by Marriott Sikeston

2. TownePlace Suites by Marriott Sikeston

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

4. Drury Inn & Suites Sikeston, MO

5. Best Western Plus Sikeston I-55

6. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

7. Comfort Inn & Suites Sikeston I-55

8. Days Inn and Suites by Wyndham Sikeston

9. Super 8 by Wyndham Sikeston/Miner Area

10. Country Yard Inn and Suite

Compare popular hotels close to Sikeston Depot Museum

Other attractions near Sikeston Depot Museum

Central Park

Top Sikeston Depot Museum Hotel Reviews

Hampton Inn Sikeston

10/10 Excellent

Frequently Asked Questions

What's the area like around Sikeston Depot Museum?

What's the best hotel to stay near Sikeston Depot Museum?

How many hotels should I expect to find close to Sikeston Depot Museum?

If I need to cancel the hotel reservation for my stay near Sikeston Depot Museum, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Sikeston Depot Museum?