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Comfort Inn & Suites Sikeston I-55

Property class: 2.5

Choose dates to view prices

You can look forward to laundry facilities, a gym, and a business center at Comfort Inn & Suites Sikeston I-55. Stay connected with free in-room WiFi.

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
The current price is AED 338
AED 385 total
includes taxes & fees
8 Sep - 9 Sep

Room options

Available filters for rooms
Showing 8 of 8 rooms

View all photos for 1 King Bed, Suite, Nonsmoking

A hotel room with a bed, two bedside tables, a lamp, a telephone, a framed picture on the wall, and a window with curtains.

1 King Bed, Suite, Nonsmoking

  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for 2 Queen Beds, Nonsmoking, Accessible

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

2 Queen Beds, Nonsmoking, Accessible

  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for 1 King Bed, Nonsmoking, Accessible

A hotel room with a bed, two bedside tables with lamps, a chair, and a patterned carpet.

1 King Bed, Nonsmoking, Accessible

  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds, Non Smoking

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

Standard Room, 2 Queen Beds, Non Smoking

8.2 out of 10
Very good
(14 reviews)
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

A hotel room with a blue sofa, a bed, a nightstand, and a lamp. There are three framed pictures on the wall.

Suite, 1 King Bed with Sofa bed, Non Smoking

  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Room, 1 King Bed, Accessible, Non Smoking

A hotel room with a large bed, a desk, a chair, and a small ottoman.

Room, 1 King Bed, Accessible, Non Smoking

8.6 out of 10
Excellent
(4 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

A hotel room with two beds, a microwave, a mini-fridge, a coffee maker, and a window with curtains.

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Non Smoking

A hotel room with a large bed, two bedside tables with lamps, a window with curtains, and a wall-mounted heater.

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(15 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

About the neighborhood

Sikeston is home to Comfort Inn & Suites Sikeston I-55. The area's natural beauty can be seen at Mississippi River and Central Park, while Sikeston Depot Museum and Front Street Studio & Art Gallery are cultural highlights. Visit our Sikeston travel guide
Map
109 Matthews Ln, Sikeston, MO, 63801

What's nearby

  • A cable-stayed bridge over a river with a rocky shoreline in the foreground.
    Riverfront Bridge Park
    28 min drive - 59.1 km
  • A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.
    Southeast Missouri State University
    31 min drive - 60.8 km
  • City of Miner Convention Center
    5 min walk - 0.4 km
  • Sikeston Depot Museum
    5 min drive - 5.9 km
  • Century Casino & Hotel Cape Girardeau
    31 min drive - 61.5 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    29 min drive

Restaurants

  • Love's Travel Stop
    6 min drive
  • Lambert's Cafe
    17 min walk
  • Buffalo Wild Wings
    5 min drive
  • McDonald's
    6 min drive
  • China Buffet
    6 min drive

About this property

Comfort Inn & Suites Sikeston I-55

  • Property highlights
  • Take advantage of laundry facilities, a gym, and a business center at Comfort Inn & Suites Sikeston I-55. Stay connected with free in-room WiFi.
  • Other perks include:
    • An indoor pool
    • Free self parking
    • Laundry services, an elevator, and a 24-hour front desk
    • A front-desk safe
    • Guest reviews give top marks for the helpful staff
  • Room features
  • All 64 rooms feature comforts such as air conditioning, in addition to amenities like free WiFi.
  • Other amenities include:
    • Bathrooms with tubs or showers
    • Cable channels, coffee/tea makers, and desks

Similar properties

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Best Western Plus Sikeston I-55
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  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
8.4 out of 10, Very Good, 1,011 reviews
The price is AED 272
AED 310 total
includes taxes & fees
23 Aug - 24 Aug
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: anytime
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 20 per pet, per night
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 20 lbs per pet)
Specific rooms only; pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)

Frequently asked questions

Does Comfort Inn & Suites Sikeston I-55 have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of 18 August 2026, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on 8 September 2026 start from AED 338, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Comfort Inn & Suites Sikeston I-55 pet-friendly?

Yes, Comfort Inn & Suites Sikeston I-55 allows cats and dogs (limit 2 total) with a maximum weight of up to 20 lbs per pet. There's a fee of USD 20 per pet, per night. Service animals are exempt from fees.

How much is parking?

Self parking is free at this property.

What time is check-in at Comfort Inn & Suites Sikeston I-55?

Check-in start time: 2:00 PM; Check-in end time: anytime.

What time is check-out at Comfort Inn & Suites Sikeston I-55?

Check-out is at 11:00 AM.

Where is Comfort Inn & Suites Sikeston I-55 located?

Situated in Sikeston, this hotel is 0.4 mi (0.6 km) from City of Miner Convention Center and within 6 mi (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9 mi (14.5 km) away.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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