Top La Quinta Inn & Suites in Southern Illinois, IL from AED 300

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois La Quinta Inn & Suites

Studio Suite, Non Smoking (1 King Bed) | Pillowtop beds, desk, blackout drapes, iron/ironing board

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport

Taylor

AED 322

AED 370 total

includes taxes & fees

6 Sep - 7 Sep

Deluxe Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

2. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Alexis

AED 378

AED 423 total

includes taxes & fees

30 Aug - 31 Aug

Room, 2 Queen Beds, Non Smoking | Premium bedding, pillowtop beds, desk, iron/ironing board

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

O'Fallon

Tahjae

AED 261

AED 300 total

includes taxes & fees

1 Sep - 2 Sep

Deluxe Room, 1 King Bed, Non Smoking | Premium bedding, down comforters, desk, iron/ironing board

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

Granite City

Weldon

AED 350

AED 402 total

includes taxes & fees

9 Aug - 10 Aug

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Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

10/10 Excellent

"We love staying here; it's both clean and quiet. The staff are very friendly and accommodating. Ashley, the bartender, was memorable. When you add in the happy hour perks and free breakfast, this luxury brand hotel is very affordable."

Drury Inn & Suites Marion

10/10 Excellent

"This was our 3rd time staying there in 2 months and everything was excellent! The free dinner and drinks is always good!"

Ramada by Wyndham Effingham

10/10 Excellent

"Staff"

The Principal Hotel

10/10 Excellent

"What a find! We were looking for a hotel outside of St.Louis and asked ChatGPT for suggestions. The overall pick was The Principal. Great ratings, great rate. We were already impressed before we reached the hotel. Columbia is a beautiful city. As we drove down Main St it was like stepping back in time. The hotel has a history you’ll have to discover for yourself. You’ll be very happy you stayed here. Graphite, the restaurant, has to-die-for desserts and Cafe on the Abbey is a must for breakfast (be sure to pick up a pecan brownie to go!). We will be back for sure."

Baymont by Wyndham Marion

10/10 Excellent

"Was a good safe clean place to sleep. Breakfast was nothing to write home about. Nothing hot. No protein. But would stay while traveling again."

Comfort Suites Mount Vernon

10/10 Excellent

"Hot tub was kinda gross. Definitely needed a water change. And the bubbles that you turn on, weren't working well"

Holiday Inn Express Metropolis by IHG

8/10 Good

"Water pressure at 5 am was limited to 1/4 it’s normal volume."

Baymont by Wyndham Effingham

8/10 Good

"We will be back. Enjoyed our stay."

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southern Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham Effingham

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

4. La Quinta Inn & Suites by Wyndham Pontoon Beach