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Our top choices for Southwest Coast Florida hotels

A modern hotel lobby with a reception desk, seating area, and a dining section.

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Brian

AED 442 total

includes taxes & fees

13 Nov - 14 Nov

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

2. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

Bruce

AED 348 total

includes taxes & fees

29 Nov - 30 Nov

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

3. Best Western Fort Myers Inn & Suites

Fort Myers

Azael

AED 328 total

includes taxes & fees

15 Nov - 16 Nov

A Drury Inn & Suites hotel with a parking lot full of cars.

4. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

AED 487 total

includes taxes & fees

1 Dec - 2 Dec

An outdoor patio with a barbecue area, seating, and string lights.

5. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes

Leo

AED 505 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a bed, a desk, a chair, and a small table.

6. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Jon B.

AED 362 total

includes taxes & fees

22 Nov - 23 Nov

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

7. Hampton Inn Fort Myers Downtown

Fort Myers River District

Donald

AED 447 total

includes taxes & fees

25 Nov - 26 Nov

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

8. Comfort Suites Fort Myers East I-75

Fort Myers

Eloan

AED 363 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

9. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas

James

AED 449 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

10. Home2 Suites by Hilton Fort Myers Colonial Blvd

Fort Myers

Julio

AED 498 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

11. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Fort Myers Beach

Kimberly

AED 379 total

includes taxes & fees

8 Nov - 9 Nov

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

12. Hampton Inn & Suites Fort Myers - Colonial Blvd

Fort Myers

Luis

AED 414 total

includes taxes & fees

22 Nov - 23 Nov

A large, clear swimming pool with multiple lounge areas and palm trees.

13. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Lance

AED 910 total

includes taxes & fees

29 Nov - 30 Nov

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

14. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

AED 280 total

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

15. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Merlin

AED 269 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with a stone fire pit, seating, and string lights.

16. SpringHill Suites by Marriott Fort Myers Estero

Estero

Nail

AED 512 total

includes taxes & fees

13 Nov - 14 Nov

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

17. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Frank

AED 291 total

includes taxes & fees

30 Nov - 1 Dec

A hotel with a covered entrance, palm trees, and a well-maintained garden.

18. Homewood Suites by Hilton - Fort Myers

Villas

Anne

AED 449 total

includes taxes & fees

22 Nov - 23 Nov

The exterior of a hotel with a covered entrance, palm trees, and a car parked outside.

19. Hyatt Place Fort Myers/at The Forum

The Forum

Cornel

AED 389 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

20. Home2 Suites by Hilton Fort Myers Airport

Fort Myers

Donna

AED 500 total

includes taxes & fees

22 Nov - 23 Nov

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Vacation Rentals in Southwest Coast Florida

Aparthotel

A pool area with lounge chairs and umbrellas, a beach with umbrellas and lounge chairs, and palm trees.

Sundial Beach Resort & Spa

Mid Island

"Love the resort and great access to beach"

Aparthotel

A beach with a thatched-roof structure, palm trees, and a view of the sea.

The Suites at Fishermen’s Village

Punta Gorda Isles

"Great place to stay but comes with a price."

Apartment

A swimming pool with lounge chairs and a building with a sloped roof in the background.

Landing Apartments Fort Myers near Eastwood Village

Fort Myers

"Amazing , safe and beautiful place to stay . I was there for over 3 weeks and it’s local to many great locations , quiet and safe and over all highly recommend."

Aparthotel

A beach with a clear sky, a palm tree, and a sandy path leading to the water.

Sanibel Siesta on the Beach

Mid Island

"Great location and close to beach. Rooms nice and it had everything you needed for the beach. Pool wonderful"

Villa

A beachside area with colorful beach houses, a dock, and a sandy beach.

Matlacha Tiny Village

Matlacha

"So cute and clean nice dock to sit and relax or fish. Kayaks available to use free as well with life jackets paddles, etc. well equipped rental we can’t wait to go again! Great communication with hosts."

Vacation Home

A spacious living area with a large window overlooking a body of water, a ceiling fan, and a modern kitchen in the background.

Lovers Key Resort by Distinctive Beach Rentals

Fort Myers Beach

"This is our second year staying at this resort and we absolutely love it! Clean, easy check in and out , safe, couldn’t ask for more!"

Apartment

A spacious living area with a curved ceiling, large windows, a dining area, and a kitchen.

Landing Furnished Apartments minutes from Downtown Fort Myers

Hancock

"Clean, quiet, perfect alternative to a hotel"

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Stay near popular Southwest Coast Florida attractions

A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Siesta Key Beach

9.6/10 (4,113 reviews)

Nothing says vacation like spending a lazy day at Siesta Key Beach, a popular beach in Siesta Key. Amble around this relaxing area's seaside or experience its live music.

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Learn more about Southwest Coast Florida

Amazing beaches, island views, and top sights from Key West Express to Siesta Key Beach—discover Southwest Coast Florida, a destination also famous for its live music scene.

See all hotels in Southwest Coast Florida