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Go beyond your typical stay in Southwestern Virginia

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Our top choices for Southwestern Virginia hotels

La Quinta Inn & Suites by Wyndham Roanoke Salem

Salem

Ahmed

AED 390 total

includes taxes & fees

22 Jun - 23 Jun

Sleep Inn Wytheville I-77 and I-81

Wytheville

George

AED 382 total

includes taxes & fees

24 Jun - 25 Jun

Comfort Suites Abingdon I-81

Abingdon

Linda

AED 385 total

includes taxes & fees

19 Jul - 20 Jul

Hyatt Place Blacksburg / University

McBryde

Prajakta

AED 342 total

includes taxes & fees

29 Jun - 30 Jun

Fairfield Inn by Marriott Christiansburg

Christiansburg

Azende

AED 347 total

includes taxes & fees

5 Jul - 6 Jul

Americas Best Value Inn & Suites Independence VA

Independence

Deborah

AED 313 total

includes taxes & fees

23 Jun - 24 Jun

Country Inn & Suites by Radisson, Roanoke, VA

Alpine Hills

Siuping

AED 451 total

includes taxes & fees

21 Jul - 22 Jul

Tru by Hilton Radford, VA

Christiansburg

Jackie

AED 319 total

includes taxes & fees

28 Jun - 29 Jun

Travelodge by Wyndham Wytheville

Wytheville

tracy

AED 241 total

includes taxes & fees

22 Jun - 23 Jun

General Francis Marion Hotel

Marion

Carol

AED 433 total

includes taxes & fees

22 Jun - 23 Jun

Spark by Hilton Wytheville Holston Rd I 81

Wytheville

Dennis

AED 326 total

includes taxes & fees

19 Jul - 20 Jul

Breakfast, lunch, dinner and brunch served

The Highlander at Radford, Tapestry Collection by Hilton

Radford

Ariel

AED 350 total

includes taxes & fees

5 Jul - 6 Jul

Comfort Inn Blacksburg University Area

Ellett - Jennelle

Jeshan

AED 301 total

includes taxes & fees

5 Jul - 6 Jul

Home2 Suites by Hilton Blacksburg - University

Airport Acres

Jessica

AED 403 total

includes taxes & fees

29 Jun - 30 Jun

Fairfield Inn & Suites by Marriott Roanoke Salem

Salem

John

AED 421 total

includes taxes & fees

28 Jun - 29 Jun

avid hotel Salem by IHG

Salem

Suzanne

AED 333 total

includes taxes & fees

19 Jul - 20 Jul

Country Inn & Suites by Radisson, Wytheville, VA

Wytheville

David

AED 458 total

includes taxes & fees

19 Jul - 20 Jul

Tru by Hilton Wytheville

Wytheville

Alan

AED 503 total

includes taxes & fees

28 Jun - 29 Jun

The Inn at Wise

Wise

Robert

AED 428 total

includes taxes & fees

23 Jun - 24 Jun

Desk, laptop workspace, blackout drapes, iron/ironing board

Comfort Inn & Suites Troutville-Roanoke North

Troutville

Scott

AED 361 total

includes taxes & fees

12 Jul - 13 Jul

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Vacation Rentals in Southwestern Virginia

Aparthotel

The West End Flats

West End

"A spacious and economical stay in a converted school building that also had a nice low key brewery on the premises. It is a bit out of the downtown, but a quick drive. The hosts were very responsive, we had a problem with the door when we arrived, but a text was immediately responded to and the problem resolved on the spot. The only complaint would be that there was trash that was not emptied in the can from the previous guest. That made us question the overall cleanliness."

Cottage

Mountain-view Blue Ridge Cabin Getaway w/ Fire Pit

Callaway

"Wonderful stay for a beautiful VT football weekend. Great place for our family. Gorgeous views and property. "

Cabin

4BR Lodge on Wolf Creek – Fishing, Hiking, New River Fun & Hokie Weekends

Narrows

"House was very clean with a well appointed kitchen. Great space for a large family with room to spread out. We love being beside the beautiful creek. "

Cottage

Cozy Damascus Cottage w/ Porch & Trail Access!

Damascus

Cabin

New River 3BR - Fishing, Kayaking, Hot tub, VT Game Weekends

Belspring

Cottage

Cozy Damascus Home < 1 Mi to Appalachian Trl

Damascus

"Very clesn, well equipped, great location"

Cottage

Walk to Roanoke River Greenway: Mountain-view Home

Riverland/Walnut Hill

"Beautiful home in a great location. Just enough room for a family of 4. Comfy house definitely felt like home away from home. Contact person is great and very responsive. "

Apartment

Bristol Escape w/ Patio, 2 Mi to Downtown!

Bristol

"It was so cozy nice weekend getaway "

Cottage

Walk to River & Trails: Cozy Damascus Cottage!

Damascus

"Perfect little cottage, newly renovated, very clean, literally 15 feet from the AT. Very much enjoyed my stay!"

Cottage

Home w/ Bunkroom: 2 Mi to Hatfield & Mccoy Trail

Bluefield

"Very nice place to stay, like brand new inside."

Cottage

Cozy Fries Escape w/ Mountain & River Views!

Fries

"The family and I loved this place. Clean, comfortable, has everything well organized, great location, great view of New River. "

Cottage

Relaxing Retreat w/ Private Dock on Claytor Lake!

Dublin

"Very nice house right on the lake. Lots of areas to sit/eat outside if it’s nice. "

Cottage

Bristol Retreat w/ Creek Access: 2 Mi to Dtwn

Bristol

"The property was amazing, settled right on a beautiful creek and the property owner was wonderful. "

Cottage

Dreamy Damascus Cabin ~ 1 Mi to Appalachian Trail

Damascus

"This cottage was beautifully decorated, inviting and relaxing. The various outdoor seating areas were lovely. The attention to detail was obvious."

Apartment

Comfy Damascus Apartment - Walkable Location

Damascus

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Stay near popular Southwestern Virginia attractions

Virginia Tech University

9.6/5 (1,791 reviews)

Enjoy the collegiate vibe around Virginia Tech University, a top college in Blacksburg. You can attend a sporting event while in the area.

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Learn more about Southwestern Virginia

Explore the family-friendly area of Southwestern Virginia—a college vibe, sports teams, and sights from Wytheville Meeting Center to Wohlfahrt Haus Dinner Theatre.

See all hotels in Southwestern Virginia

Top Southwestern Virginia Hotel Reviews

Sleep Inn Wytheville I-77 and I-81

10/10 Excellent

"Sleep Inn is conveniently located and easy to access. The front desk staff were friendly, welcoming, and very helpful throughout our stay. The room was clean, comfortable, and free of any unpleasant odors. One feature I particularly appreciated was that the window could be opened slightly, allowing fresh air to circulate through the room and making the environment feel much fresher and more pleasant. The breakfast offered a good selection of food. The only minor drawback was that the dining area was a bit small, so it could become crowded during peak breakfast hours. It would also be helpful if the breakfast hours could be extended slightly, giving guests more flexibility and helping to reduce congestion during busy times. Overall, Sleep Inn provides good value for the money. I enjoyed my stay and would be happy to stay here again in the future."

Hard Rock Hotel & Casino Bristol

10/10 Excellent

"It was our first time here. All employees were very pleasant and helpful. The music is great. Dining at Council Oaks steak and seafood was a great experience. Will definitely be back for that. Pool was very nice and well maintained. Bartenders and servers will go out of their way to make you feel on vacation. Rooms are pricey - nothing too showy- but they do the job. We don’t gamble and still had a great time."