Midtown, MO

St. Louis

Midtown
Photo by throwingsofas
Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit


Midtown Hotel Deals

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue, St. Louis, MO
The price is AED 496 per night from Sep 28 to Sep 29
AED 496
per night
Sep 28 - Sep 29
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (588 reviews)
"The hotel was fantastic for our family and the weekend we had in St Louis. The staff was so nice and my little kid enjoyed meeting everyone that works there. Highly recommend staying here and will probably do so again in the soon future."

Reviewed on 15 September 2025

Element St. Louis Midtown
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
The price is AED 441 per night from Sep 28 to Sep 29
AED 441
per night
Sep 28 - Sep 29
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,066 reviews)
Wonderful stay
"The hotel staff was amazing! Not just one or two, but EVERY staff member we came into contact with was so friendly and welcoming. Very refreshing! Location was amazing right next to the arch. We loved the breakfast and the 5:30 kickback. This was our first stay at a Drury hotel and definitely our ..."

Reviewed on 19 September 2025

Drury Plaza Hotel St. Louis at the Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
The price is AED 323 per night from Oct 19 to Oct 20
AED 323
per night
Oct 19 - Oct 20
Stay at this 3.5-star business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,149 reviews)
"Great places to jo"

Reviewed on 18 September 2025

Hollywood Casino & Hotel St. Louis
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road, St. Louis, MO
The price is AED 452 per night from Oct 3 to Oct 4
AED 452
per night
Oct 3 - Oct 4
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,007 reviews)
"!"

Reviewed on 19 September 2025

Renaissance St. Louis Airport Hotel
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
The price is AED 362 per night from Oct 5 to Oct 6
AED 362
per night
Oct 5 - Oct 6
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,939 reviews)
"Staff was helpful and shower was excellent."

Reviewed on 17 September 2025

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
The price is AED 459 per night from Oct 2 to Oct 3
AED 459
per night
Oct 2 - Oct 3
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,979 reviews)
"We will come back. The room we had is the best for full view of the arch."

Reviewed on 17 September 2025

Hyatt Regency St. Louis at The Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Midtown

Default Image

The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

The Gate
St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Downtown West
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.

Lafayette Square
Default Image

Shaw

4.5/5(3 area reviews)

While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Shaw
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

The Grove