Photo by Visit Greenville, South Carolina

Find hotels in Upstate South Carolina, SC from AED 246
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Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
10.0 out of 10, Exceptional, (1 review)
The price is AED 202
AED 224 total
includes taxes & fees
19 May - 20 May

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is AED 231
AED 255 total
includes taxes & fees
19 May - 20 May

Clemson Memorabilia House
Clemson Memorabilia HouseClemson
9.6 out of 10, Exceptional, (10 reviews)
The price is AED 327
AED 872 total
includes taxes & fees
18 May - 19 May

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very Good, (702 reviews)
The price is AED 303
AED 356 total
includes taxes & fees
14 Jun - 15 Jun

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is AED 584
AED 953 total
includes taxes & fees
19 May - 20 May

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,005 reviews)
The price is AED 400
AED 497 total
includes taxes & fees
19 May - 20 May

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (230 reviews)
The price is AED 475
AED 522 total
includes taxes & fees
24 May - 25 May

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (717 reviews)
The price is AED 305
AED 333 total
includes taxes & fees
31 May - 1 Jun

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (790 reviews)
The price is AED 374
AED 419 total
includes taxes & fees
25 May - 26 May

Urban Boutique Hotel, BW Signature Collection
Urban Boutique Hotel, BW Signature CollectionGreenville
8.0 out of 10, Very Good, (1,003 reviews)
The price is AED 237
AED 261 total
includes taxes & fees
31 May - 1 Jun

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (458 reviews)
The price is AED 511
AED 557 total
includes taxes & fees
7 Jun - 8 Jun

Best Western Seneca-Clemson
Best Western Seneca-ClemsonSeneca
8.4 out of 10, Very Good, (659 reviews)
The price is AED 359
AED 395 total
includes taxes & fees
20 May - 21 May

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (615 reviews)
The price is AED 404
AED 448 total
includes taxes & fees
24 May - 25 May

Aloft by Marriott Greenville Downtown
Aloft by Marriott Greenville DowntownGreenville Downtown
9.2 out of 10, Wonderful, (1,002 reviews)
The price is AED 476
AED 539 total
includes taxes & fees
24 May - 25 May

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,011 reviews)
The price is AED 547
AED 607 total
includes taxes & fees
18 May - 19 May

Days Inn by Wyndham Greenville South/Mauldin
Days Inn by Wyndham Greenville South/MauldinMauldin
7.6 out of 10, Good, (695 reviews)
The price is AED 265
AED 292 total
includes taxes & fees
31 May - 1 Jun

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very Good, (1,005 reviews)
The price is AED 403
AED 447 total
includes taxes & fees
7 Jun - 8 Jun

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (710 reviews)
The price is AED 449
AED 498 total
includes taxes & fees
7 Jun - 8 Jun

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,206 reviews)
The price is AED 436
AED 479 total
includes taxes & fees
24 May - 25 May

Hilton Garden Inn Anderson
Hilton Garden Inn AndersonAnderson
9.0 out of 10, Wonderful, (725 reviews)
The price is AED 365
AED 405 total
includes taxes & fees
24 May - 25 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (73 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is AED 222 per night from Jun 11 to Jun 12
AED 222
AED 246 total
11 Jun - 12 Jun
includes taxes & fees
6/10 (601 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
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