A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina Vacations

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Top destinations in Upstate South Carolina

A riverside walkway with cyclists, a bridge, and modern buildings.

Discover the most popular places to visit in Upstate South Carolina

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Walk around the campus of Clemson University, a top university in Clemson. Experience the area's theater scene or attend a football game.

Upstate South Carolina Hotel Deals

Room, 1 King Bed | Bathroom | Towels

Carolina Inn Anderson Clemson Area

45 km from Upstate South Carolina

"Very noisy AC. Stained carpets and towels"

AED 244 total

includes taxes & fees

21 Jul - 22 Jul

Premium bedding, in-room safe, laptop workspace, WiFi (free)

Carolina Camp Cedar

37.8 km from Upstate South Carolina

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

AED 974 total

includes taxes & fees

21 Jul - 22 Jul

See all properties in Upstate South Carolina