Cheap Flights from Knoxville (TYS) to Colon (ONX)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save on select hotels after you book a flight*
  • trophy illustration

    Find the right fit

    We search billions of combinations of flights to help you find your next adventure

Frequently asked questions

Is it cheaper to buy a plane ticket from TYS to ONX last minute?
When it's time to book your flights, it's better to be prepared. While it's possible to pick up a last-minute deal on a TYS to ONX flight, prices usually don't get cheaper as the departure date nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to lock in a domestic flight is between 28 – 35 days ahead. For international trips it's between three and four months.
What airports do you fly into for Colon from Knoxville?
There are three airports you can fly into on your trip from Knoxville to Colon: Colon (ONX-Enrique Adolfo Jimenez), Marcos A. Gelabert Intl. Airport (PAC) and Tocumen Intl. Airport (PTY). Colon (ONX-Enrique Adolfo Jimenez) is around 3 kilometers east of downtown Colon. Before deciding where to touch down, consider ticket prices, the distance to your next stop and the convenience and cost of getting from the airport.
Can I change the date of my flight from Knoxville Airport to ONX?
Make changes quickly to your TYS to ONX journey by logging in to the Expedia Trips portal. But before you make any amendments, read the conditions and rules in your itinerary to see what you're able to do and whether fees apply. Some carriers have a change fee per person, in addition to any difference in airfares. But if you booked in the last 24 hours, you may be able to cancel for free and organize new flights. You can also swing by our Customer Service portal for more info and to connect with our Virtual Agent.

Travel information

Origin airport
McGhee Tyson
Destination airport
Enrique Adolfo Jimenez
Distance
2952 km

Book with confidence