Cheap Flights from Houston (HOU) to São Tomé Island (TMS)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save on select hotels after you book a flight*
    trophy illustration

    Find the right fit

    We search billions of combinations of flights to help you find your next adventure

Frequently asked questions

Is it cheaper to buy a plane ticket from HOU to Sao Tome Intl. Airport last minute?
When it comes to booking your flights, being organized pays off. While you may be able to score a deal on a William P. Hobby Airport (HOU) to Sao Tome Intl. Airport (TMS) flight at the last minute, tickets usually don't get cheaper as the date of departure nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days in advance. For international trips it's between three and four months.
What airports do you fly into for São Tomé Island from Houston?
Houston to São Tomé Island flights arrive at Sao Tome Intl. Airport (TMS). The terminal is approximately 21 kilometers northeast of central São Tomé Island. Land a fantastic airfare with Expedia and then get set for an adventure.
Can I change the date of my flight from HOU to Sao Tome Intl. Airport?
It's a piece of cake to make amendments to your William P. Hobby Airport to TMS trip yourself. Just log in to the Expedia Trips portal and hit "change flight." Look around for new flights and secure the one that fits your new plans. You'll see an estimate of applicable flight change fees. Alternatively, head to our Customer Service portal to connect with our Virtual Agent and get answers to your questions.

Travel information

Travel information

Origin airport
William P. Hobby
Destination airport
São Tomé Intl.
Distance
11077 km

Book with confidence

Book with confidence