Cheap Flights from Knoxville (TYS) to Des Moines (DSM)

Popular airlines from McGhee Tyson Airport (TYS) to Des Moines International Airport (DSM)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save on select hotels after you book a flight*
    trophy illustration

    Find the right fit

    We search billions of combinations of flights to help you find your next adventure

Frequently asked questions

Is it cheaper to buy a plane ticket from TYS to Des Moines Intl. Airport (DSM) last minute?
Booking your journey from McGhee Tyson Airport (TYS) to DSM last minute could save you money if you hit the jackpot and find an amazing deal. However, fares typically don't come down in price as the departure date nears. If you hold out, flights could also be sold out or the best seats gone (because no one wants the middle seat). If you want to be on the safe side, book well in advance of the date you want to leave. In fact, some of the best deals are available on Expedia up to a year in advance. If your preferred carrier hasn't released its airfares yet, check back regularly as deals are updated on Expedia all the time.
What airports do you fly into for Des Moines from Knoxville?
You can travel from Knoxville to Des Moines through both Des Moines Intl. Airport (DSM) and Marshalltown, IA (MIW-Marshalltown Municipal). Land at Des Moines Intl. Airport (DSM) and you'll be about 6 kilometers to the southwest of downtown Des Moines. Leave your bags at your hotel and then explore some of the city's famous sights, including Iowa State Fairgrounds and Blank Park Zoo.
Can I change the date of my flight from McGhee Tyson Airport (TYS) to DSM?
Easily make changes to your McGhee Tyson Airport (TYS) to DSM trip by logging in to the Expedia Trips portal. But before you make any adjustments, check out the rules in your itinerary to see what the airline will let you do and if charges apply. Some airlines charge a change fee per person, plus any difference in ticket prices. However, if you booked in the last 24 hours, you may be able to cancel for free and organize new flights. You can also take a look at our Customer Service portal for further details and to chat with our Virtual Agent.

Travel information

Origin airport
McGhee Tyson
Destination airport
Des Moines Intl.
Distance
1045 km

Book with confidence