Find 4 Star Hotels in Defiance, MO from AED 468
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Compare Defiance 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hilton St. Louis Frontenac
Frontenac
8.8 out of 10, Excellent, (1002)
The price is AED 410
AED 477 total
includes taxes & fees
20 Dec - 21 Dec

Ameristar Casino Resort and Spa
St. Charles
8.4 out of 10, Very Good, (1007)
The price is AED 526
AED 676 total
includes taxes & fees
7 Dec - 8 Dec

DoubleTree by Hilton St. Louis - Westport
Maryland Heights
8.2 out of 10, Very Good, (1004)
The price is AED 404
AED 468 total
includes taxes & fees
28 Dec - 29 Dec

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
8.6 out of 10, Excellent, (1006)
The price is AED 449
AED 521 total
includes taxes & fees
20 Dec - 21 Dec

The Inn at Elijah McLeans
Washington
8.8 out of 10, Excellent, (133)
The price is AED 436
AED 497 total
includes taxes & fees
9 Dec - 10 Dec

Historic Main Street Heritage Retreat
St. Charles Historic District
9.4 out of 10, Exceptional, (37)

Landing Apartments - Eureka
Eureka
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Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Hilton St. Louis Frontenac
10/10 Excellent
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Defiance Hotels by Star Rating
Stay near popular Defiance attractions
- Hotels near Chandler Hill Vineyards
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Yellow Farmhouse Winery
- Hotels near Sugar Creek Winery
- Hotels near Broemmelsiek Park
- Hotels near Ameristar Casino St. Charles
- Hotels near Six Flags St. Louis
- Hotels near Mississippi River
- Hotels near Hollywood Casino Amphitheatre
- Hotels near St Charles Convention Center
- Hotels near Westport Plaza
- Hotels near Hidden Valley Ski Resort
- Hotels near Route 66 State Park
- Hotels near Magic House - St. Louis Children's Museum
- Hotels near St. Louis Premium Outlets
- Hotels near Purina Farms
- Hotels near Lindenwood University
- Hotels near Family Arena
- Hotels near Historic Main Street
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Explore more hotels
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