
Find 2 Star Hotels in Defiance, MO from AED 244
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Our top choices for Defiance 2-star hotels
The price is AED 227
AED 261 total
includes taxes & fees
17 Jan - 18 Jan

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles InnSt. Charles
5.8 out of 10, (1,004 reviews)
The price is AED 219
AED 253 total
includes taxes & fees
18 Jan - 19 Jan

Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic DistrictSt. Charles Historic District
9.4 out of 10, Exceptional, (1,000 reviews)
The price is AED 410
AED 471 total
includes taxes & fees
25 Jan - 26 Jan

8.0 out of 10, Very Good, (1,000 reviews)
The price is AED 328
AED 377 total
includes taxes & fees
5 Feb - 6 Feb

8.0 out of 10, Very Good, (1,000 reviews)

8.4 out of 10, Very Good, (1,003 reviews)
The price is AED 278
AED 320 total
includes taxes & fees
25 Jan - 26 Jan

8.0 out of 10, Very Good, (1,030 reviews)
The price is AED 278
AED 322 total
includes taxes & fees
19 Jan - 20 Jan

Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHGO'Fallon
8.6 out of 10, Excellent, (858 reviews)
The price is AED 349
AED 412 total
includes taxes & fees
18 Jan - 19 Jan
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Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Defiance.

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
The price is AED 312 per night from Feb 1 to Feb 2
AED 312
AED 361 total
1 Feb - 2 Feb
includes taxes & fees
7.8/10 Good! (1,073 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Relax Inn Saint Charles
10/10 Excellent
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Defiance Hotels by Star Rating
Stay near popular Defiance attractions
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Six Flags St. Louis
- Hotels near Ameristar Casino St. Charles
- Hotels near Mississippi River
- Hotels near Hollywood Casino Amphitheatre
- Hotels near St Charles Convention Center
- Hotels near Westport Plaza
- Hotels near Purina Farms
- Hotels near Hidden Valley Ski Resort
- Hotels near Magic House - St. Louis Children's Museum
- Hotels near Route 66 State Park
- Hotels near Lindenwood University
- Hotels near Hollywood Casino
- Hotels near Missouri River
- Hotels near Family Arena
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Explore more hotels
- Drury Inn & Suites Southwest St. Louis
- Hampton Inn St. Charles St. Peters
- The St. Charles Guest House, lovely historic home, fun for families and groups
- Drury Plaza Hotel St. Louis St. Charles
- Comfort Suites St Charles - St Louis
- Embassy Suites by Hilton St. Louis St. Charles
- Crowne Plaza St. Louis Airport by IHG
- Wingate by Wyndham St. Louis/Fenton Route 66
- Drury Inn & Suites St. Louis St. Peters
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Drury Plaza Hotel St. Louis Chesterfield
- Hampton Inn & Suites St. Charles Old Town Area
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- Drury Plaza Hotel St. Louis Creve Coeur
- Fairfield Inn & Suites by Marriott St. Louis Chesterfield
- Hilton St. Louis Frontenac
- Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
- Extended Stay America Suites St Louis St Peters
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