A coastal landscape with rocky cliffs, green hills, and a clear blue sea.

Find 4 Star Hotels in Mediterranean Region from AED 354

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mediterranean Region 4 Star Hotels

Tonight
29 Sep - 30 Sep
Tomorrow
30 Sep - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Mediterranean Region 4-star hotels

A spacious lobby with modern seating arrangements, a large digital screen displaying a scenic view, and a high ceiling with natural light.
A multi-level interior with glass railings and a geometric ceiling design.
A buffet with various food items and dishes.
A modern hotel room with a bed, bedside table, lamp, and a bathroom visible through a glass partition.

1. Barcelona Airport Hotel

Barcelona Airport Hotel
El Prat de Llobregat
United States
Craig
AED 593
AED 669 total
includes taxes & fees
29 Oct - 30 Oct
Barcelona Airport Hotel
A modern hotel interior with a central hallway, multiple balconies, and a sign reading 'HOTEL 101 MADRID'.
A gym with treadmills, elliptical machines, and weight benches.
A hotel entrance with a revolving door, glass doors, and a reception area with seating.
A modern indoor pool with lounge chairs, a tiled floor, and a building with balconies.

2. Hotel101- Madrid

Hotel101- Madrid
Barajas
Canada
Madine
AED 322
AED 354 total
includes taxes & fees
4 Oct - 5 Oct
Hotel101- Madrid
The exterior of a building with a prominent "BARCELONA" sign.
A hotel lobby with a reception desk, bar area, and seating.
A reception area with a granite counter, a clock, and a reception desk.
A buffet with various food items and condiments, a red vase, and two monitors on the wall.

3. Hotel 3K Barcelona

Hotel 3K Barcelona
Lisbon City Center
United Kingdom
Guilherme
AED 428
AED 487 total
includes taxes & fees
16 Oct - 17 Oct
Hotel 3K Barcelona
A modern living room with a sofa, a coffee table, and a bookshelf.
A balcony with breakfast items, two glasses of juice, and a view of a statue and building facade.
A modern hotel room with a sofa, a bed, a coffee table, and a framed artwork on the wall.
A modern bathroom with a large mirror, a robe hanging on a rack, and a towel shelf.

4. Hotel Regina

Hotel Regina
Madrid Centro
United States
Peter
AED 1,146
AED 1,261 total
includes taxes & fees
30 Sep - 1 Oct
Hotel Regina
A rooftop pool area with modern loungers and a city view.
A modern restaurant with wooden tables and chairs, a bar area, and large windows offering a view of the outdoors.
A bar area with a marble counter, bar stools, and a view of the cityscape.
A modern indoor seating area with sofas and tables, large windows, and indoor plants.

5. The Stanley

The Stanley
Athens City Centre
United States
Hong
AED 429
AED 530 total
includes taxes & fees
25 Oct - 26 Oct
The Stanley
A Radisson hotel with a modern design, featuring a prominent sign and multiple floors.
A modern hotel lobby with a buffet area, marble flooring, and large mirrors.
A modern hotel lobby with marble flooring, a central staircase, and a reception area.
A modern lobby with marble walls, a large abstract mural, and a staircase.

6. Radisson Blu Hotel

Radisson Blu Hotel
Lisbon City Center
United States
Adalberto
AED 470
AED 531 total
includes taxes & fees
26 Oct - 27 Oct
Radisson Blu Hotel
A bar area with chairs and a table, overlooking a cityscape with buildings and a dome structure.
A hotel lobby with a circular ceiling light, a reception desk, and a seating area with sofas.
A pool area with multiple white umbrellas and a clear view of the city skyline.
A breakfast table with a variety of food items, a glass of orange juice, and a cup of coffee.

7. Hotel Riu Plaza España

Hotel Riu Plaza España
Madrid Centro
United States
Alejandro
AED 738
AED 812 total
includes taxes & fees
28 Oct - 29 Oct
Hotel Riu Plaza España
A swimming pool with blue and white stripes, a large building with a dome, and a cityscape in the background.
A spacious lobby with seating areas, a reception desk, and a modern ceiling design.
A balcony with wicker chairs and a small table, overlooking a cityscape with historic buildings and a dome structure.
A buffet with various pastries and desserts.

8. Urban Hive Madrid

Urban Hive Madrid
Madrid Centro
Canada
Victoria
AED 698
AED 768 total
includes taxes & fees
18 Oct - 19 Oct
Urban Hive Madrid
A hallway with wooden flooring, grey walls, and two elevators.
A cityscape with modern high-rise buildings, including a distinctive curved skyscraper and a tall rectangular building with illuminated signage.
A large hall with rows of blue chairs, a high arched ceiling, and emergency exit signs.
A hotel room with a bed, a desk with a computer, a chair, a small table with a cup and book, and a window with curtains.

9. Hotel Chamartin The One

Hotel Chamartin The One
Chamartín
United States
Jessy
AED 539
AED 593 total
includes taxes & fees
18 Oct - 19 Oct
Hotel Chamartin The One
A modern lobby with a staircase, seating area, and a reception desk.
The entrance of Hotel Liabeny with a sign above the doors and flags on the facade.
A modern hotel room with a bed, bedside tables, a desk, a chair, and a TV mounted on the wall.
A modern restaurant with round tables and cushioned chairs, a bar area with copper taps, and a large pillar structure.

10. Hotel Liabeny

Hotel Liabeny
Madrid Centro
United States
Corina
AED 880
AED 968 total
includes taxes & fees
27 Oct - 28 Oct
Hotel Liabeny
Terrace/patio
Pool
Bar (on property)
Bar (on property)

11. Locke de Santa Joana

Locke de Santa Joana
Lisbon City Center
United Kingdom
Ian
AED 446
AED 506 total
includes taxes & fees
25 Oct - 26 Oct
Locke de Santa Joana
A modern hotel lobby with a glass wall, seating areas, and a staircase leading to an upper level.
A rooftop terrace with two wicker lounge chairs, a small round table with a bottle and glasses, and a potted plant.
A long, narrow hotel corridor with doors on both sides, a carpeted floor, and overhead lighting.
A modern cafe with glass partitions, tables, and chairs.

12. Hotel América Sevilla

Hotel América Sevilla
Historical Center
United States
Maria C
AED 617
AED 679 total
includes taxes & fees
1 Oct - 2 Oct
Hotel América Sevilla
A modern restaurant with a variety of seating options, including tables and chairs, and a central display case with food items.
A modern building with a pool area, lounge chairs, and a sign indicating amenities like 'chegadas arrivals' and 'parque parking'.
A spacious lobby with a high ceiling, large windows, and modern seating arrangements.
A modern indoor pool area with lounge chairs and a reception desk.

13. Meliá Lisboa Aeroporto

Meliá Lisboa Aeroporto
Lisbon
United States
Peo
AED 824
AED 906 total
includes taxes & fees
30 Oct - 31 Oct
Meliá Lisboa Aeroporto
A modern hotel room with a large bed, a bathtub, and a seating area with a view of the city.
A modern outdoor seating area with a glass balustrade, potted plants, and a view of the cityscape.
A modern hotel with a glass facade, illuminated by blue lights, and a visible 'HOTEL' sign.
A spacious hotel lobby with a central spiral light fixture, comfortable seating areas, and a clear view of the upper floors.

14. Hard Rock Hotel Madrid

Hard Rock Hotel Madrid
Palos de la Frontera
United States
Robert
AED 978
AED 1,076 total
includes taxes & fees
30 Oct - 31 Oct
Hard Rock Hotel Madrid
A swimming pool with lounge chairs and umbrellas, surrounded by greenery and a building in the background.
A modern, well-lit hallway with a wooden floor, white walls, and potted plants.
A modern outdoor dining area with white furniture and a pool in the background.
A modern kitchen with a bar area, featuring a coffee machine, various bottles, and a large window with a view of greenery.

15. Italiana Hotels Florence

Italiana Hotels Florence
Florence
United States
Daniel
AED 335
AED 427 total
includes taxes & fees
28 Oct - 29 Oct
Italiana Hotels Florence
An outdoor cafe with tables and chairs, a view of the street, and buildings in the background.
A hotel reception area with a wooden reception desk, a glass door entrance, and a view of the street outside.
A hotel facade with a sign reading "HOTEL DELLE NAZIONI".
A modern dining area with patterned chairs, tables, and potted plants.

16. Hotel Delle Nazioni

Hotel Delle Nazioni
Rome City Centre
United States
eric
AED 1,343
AED 1,540 total
includes taxes & fees
25 Oct - 26 Oct
Hotel Delle Nazioni
A modern hotel room with two beds, a desk, a chair, a TV, and a view of the city.
A modern interior with a central staircase, glass railings, and a control desk area.
A modern buffet setup with multiple food stations, each with a glass display case and a variety of dishes.
A modern hotel room with a large window, a flat-screen TV, a sofa, a coffee table, and a bed.

17. Barceló Sants

Barceló Sants
Sants-Montjuïc
Hong Kong SAR China
KaFungKriztine
AED 675
AED 820 total
includes taxes & fees
26 Oct - 27 Oct
Barceló Sants
A narrow alleyway with a stone archway, potted plants, and a hanging lantern.
A spacious courtyard with arches, a balcony, wicker furniture, potted plants, and a tiled floor.
A courtyard with yellow buildings, potted plants, and a cobblestone path.
A building with arches, a tiled roof, and a stone facade.

18. Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
Historical Center
United Kingdom
Gene
AED 816
AED 898 total
includes taxes & fees
25 Oct - 26 Oct
Las Casas de la Judería, Sevilla Historic City Center
A rooftop restaurant with tables set for dining, overlooking a cityscape.
A rooftop restaurant with white wicker furniture, tables set with white tablecloths, and red flowers. A view of a cityscape with historic buildings is visible in the background.
A lobby with a fireplace, red and blue chairs, marble walls, and wall sconces.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and several balconies.

19. Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo
Rome City Centre
United States
Steven
AED 818
AED 963 total
includes taxes & fees
30 Oct - 31 Oct
Bettoja Hotel Mediterraneo
A dining area with round tables and purple chairs, large windows with a city view, and a red sofa.
A multi-story hotel with a classic architectural style, featuring balconies and illuminated windows.
A bar with various drinks and bottles, a fruit bowl, and a cityscape with mountains in the background.
A modern hotel room with a large bed, a desk, and a chair.

20. Marcella Royal Hotel - Rooftop Garden

Marcella Royal Hotel - Rooftop Garden
Rome City Centre
United States
Yaranett
AED 1,014
AED 1,178 total
includes taxes & fees
27 Oct - 28 Oct
Marcella Royal Hotel - Rooftop Garden
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mediterranean Region.
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Avenida Catedral, 7 Barcelona
AED 1,277
AED 1,515 total
29 Oct - 30 Oct
includes taxes & fees
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
Grand Hyatt Barcelona

Grand Hyatt Barcelona

Plaza de Pio XII, 4 Barcelona
AED 818
AED 1,010 total
16 Oct - 17 Oct
includes taxes & fees
9.2/10 Wonderful! (1,618 reviews)
Grand Hyatt Barcelona
Grand Hyatt Athens

Grand Hyatt Athens

115, Syngrou Avenue Athens Attica
AED 470
AED 598 total
25 Oct - 26 Oct
includes taxes & fees
Grand Hyatt Athens
Still don't see what you're looking for?
See all properties in Mediterranean Region.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mediterranean Region

During your stay in Mediterranean Region, you can discover things to see and do in the local area.

See all hotels in Mediterranean Region
A coastal sunset with pink and purple clouds over the ocean.

Top Mediterranean Region Hotel Reviews

Hotel101- Madrid

Hotel101- Madrid

10/10 Excellent
"Excellent hotel"
Fiona 3-night trip
Posted 1 hour ago
Hotel101- Madrid
Hotel Riu Plaza España

Hotel Riu Plaza España

10/10 Excellent
"Always a great stay in Madrid! We have stayed at Hotel Riu Plaza España several times, and whenever we visit Madrid, it continues to be our favorite place to stay. The location is excellent, right in the heart of the city and perfect for exploring Madrid. We really enjoy the hotel’s facilities, the wonderful breakfast buffet with plenty of options, and especially the rooftop, which has amazing views and a great atmosphere. We also love El Edén restaurant. Another highlight is the staff — always friendly, professional, and attentive, making us feel very welcome every time we return. It says a lot about a hotel when you keep choosing it trip after trip. We always have a wonderful experience here and will definitely stay again on our next visit to Madrid. Highly recommended! ❤️"
Tania 2-night trip
Posted 2 hours ago
Hotel Riu Plaza España
Hotel Regina

Hotel Regina

10/10 Excellent
"Great hotel all around"
Fiege 4-night trip
Posted 8 hours ago
Hotel Regina
Barcelona Airport Hotel

Barcelona Airport Hotel

10/10 Excellent
"Nice hotel near airport with on-site restaurants. They offer free shuttle to and from airport!"
Tina 1-night trip
Posted 11 hours ago
Barcelona Airport Hotel
Hilton Garden Inn Rome Airport

Hilton Garden Inn Rome Airport

8/10 Good
"No breakfast was offered for early departure."
Mark 1-night trip
Posted 11 hours ago
Hilton Garden Inn Rome Airport
Hôtel Saint Georges

Hôtel Saint Georges

8/10 Good
"L’hôtel était parfait, mais le wi-fi promis dans les chambres a été inaccessible pendant tout notre séjour, malgré l’avis qui avait été donné à la réception"
Josee 2-night trip
Posted 2 days ago
Hôtel Saint Georges
Hotel 3K Barcelona

Hotel 3K Barcelona

8/10 Good
"The hotel is conveniently located as it is close to the airport. It is also close to metro stations. The hotel could use new pillows as the ones in our room were flat, and the towels also smelt damp. It does not seem that early check-in is an option, even if an hour or two earlier than the 3 PM check-in time. Otherwise, our stay at the hotel was decent."
Denice 6-night trip
Posted 2 days ago
Hotel 3K Barcelona