Find 4 Star Hotels in Texas Medical Center, TX from AED 466

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Texas Medical Center 4 Star Hotels

This weekend
Next weekend

Our top choices for Texas Medical Center 4-star hotels

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston
4.0 star property
Downtown Houston
8.6 out of 10, Excellent, (4,113 reviews)
"Great location, friendly attentive staff."
United States
Rose
The price is AED 404
AED 472 total
includes taxes & fees
21 May - 22 May
Club Quarters Hotel Downtown, Houston

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
Greater Uptown
8.4 out of 10, Very Good, (3,898 reviews)
"Great place to stay"
United States
Jose Luis
The price is AED 475
AED 560 total
includes taxes & fees
29 May - 30 May
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,820 reviews)
"Great hotel. Very convenient and comfortable for business trips and trips to the medical center. "
United States
Byron
The price is AED 555
AED 649 total
includes taxes & fees
29 May - 30 May
Blossom Hotel Houston, Curio Collection by Hilton

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1,011 reviews)
"Wonderful and helpful staff!"
United States
Ashlee
The price is AED 724
AED 1,013 total
includes taxes & fees
25 May - 26 May
Hotel Zaza Houston Museum District

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria
8.6 out of 10, Excellent, (1,859 reviews)
"Would stay here again. Very central, clean & excellent service. "
United States
Saamia
The price is AED 451
AED 527 total
includes taxes & fees
3 May - 4 May
The Royal Sonesta Houston Galleria

The Whitehall Houston

The Whitehall Houston
4.0 star property
Downtown Houston
8.6 out of 10, Excellent, (2,165 reviews)
"Great place to stay for work meetings. Close to where I need to be. Great place to stay. "
United States
Jacob
The price is AED 496
AED 581 total
includes taxes & fees
18 May - 19 May
The Whitehall Houston

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,325 reviews)
"We really enjoyed our stay here, I think this will be our go to spot when we just want to get away from the house for the weekend."
United States
LINDA
The price is AED 591
AED 696 total
includes taxes & fees
29 May - 30 May
Hyatt Regency Houston/Galleria

The Westin Galleria Houston

The Westin Galleria Houston
4.5 star property
The Galleria
9.0 out of 10, Wonderful, (1,007 reviews)
"Great place to stay"
United States
David
The price is AED 777
AED 1,028 total
includes taxes & fees
29 May - 30 May
The Westin Galleria Houston

DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
Greenway Plaza-Upper Kirby
8.4 out of 10, Very Good, (1,570 reviews)
"The room was clean, the location near Lakewood is why I stay here. "
United States
Cathy
The price is AED 424
AED 496 total
includes taxes & fees
15 May - 16 May
DoubleTree by Hilton Hotel Houston - Greenway Plaza

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very Good, (1,892 reviews)
"Excellent stay while there for a tournament near NRG. Perfect location. The staff was so wonderful! "
United States
Lindsy
The price is AED 403
AED 475 total
includes taxes & fees
24 May - 25 May
Hilton Houston Plaza/Medical Center

Omni Houston Hotel

Omni Houston Hotel
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,004 reviews)
"Great place to stay in Houston "
United States
Rakeshkumar
The price is AED 658
AED 781 total
includes taxes & fees
10 May - 11 May
Omni Houston Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel
4.0 star property
Downtown Houston
9.2 out of 10, Wonderful, (1,491 reviews)
"Everything was fantastic and would absolutely stay here again."
United States
jonathan scott
The price is AED 485
AED 579 total
includes taxes & fees
24 May - 25 May
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Marriott Marquis Houston

Marriott Marquis Houston
4.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1,105 reviews)
"Beautiful hotel, very nice staff"
United States
Crystal
The price is AED 1,128
AED 1,427 total
includes taxes & fees
23 May - 24 May
Marriott Marquis Houston

Houston Marriott Westchase

Houston Marriott Westchase
4.0 star property
Westchase
8.4 out of 10, Very Good, (1,010 reviews)
"it was a good stay, recommended. "
United States
Yanwen
The price is AED 397
AED 466 total
includes taxes & fees
22 May - 23 May
Houston Marriott Westchase

The Moran CITYCENTRE

The Moran CITYCENTRE
4.0 star property
Memorial
9.0 out of 10, Wonderful, (1,017 reviews)
"Excellent stay "
United States
Anthony
The price is AED 608
AED 820 total
includes taxes & fees
23 May - 24 May
The Moran CITYCENTRE

The Westin Oaks Houston at the Galleria

The Westin Oaks Houston at the Galleria
4.0 star property
The Galleria
9.2 out of 10, Wonderful, (1,003 reviews)
"Great location in the Galeria. Clean and ample rooms."
United States
Hernan
The price is AED 777
AED 1,028 total
includes taxes & fees
29 May - 30 May
The Westin Oaks Houston at the Galleria

Houston Marriott Sugar Land

Houston Marriott Sugar Land
4.0 star property
First Colony
8.6 out of 10, Excellent, (1,002 reviews)
"The room was large and clean, very comfortable bed. Great location. "
United States
Tatyana
The price is AED 558
AED 652 total
includes taxes & fees
15 May - 16 May
Houston Marriott Sugar Land

Thompson Houston, by Hyatt

Thompson Houston, by Hyatt
4.0 star property
Fourth Ward
9.4 out of 10, Exceptional, (263 reviews)
"Great hotel"
United States
Joshua
The price is AED 1,028
AED 1,360 total
includes taxes & fees
21 May - 22 May
Thompson Houston, by Hyatt

Hilton Americas-Houston

Hilton Americas-Houston
4.0 star property
Downtown Houston
9.4 out of 10, Exceptional, (1,719 reviews)
"Great place to stay "
United States
Suzanne Jeanette
The price is AED 648
AED 765 total
includes taxes & fees
24 May - 25 May
Hilton Americas-Houston

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,007 reviews)
"Beautiful property "
United States
Halona
The price is AED 599
AED 774 total
includes taxes & fees
29 May - 30 May
InterContinental Houston by IHG
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Texas Medical Center.
Still don't see what you're looking for?
See all properties in Texas Medical Center.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Texas Medical Center Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Texas Medical Center?
Blossom Hotel Houston and DoubleTree by Hilton Houston Medical Center Hotel & Suites are two highly recommended getaways located in or near Texas Medical Center. Both have a 4-star rating and promise high-end comfort alongside an unrivaled guest experience. Check in to the first and get access to designer toiletries and a rooftop terrace. The second features premium bedding and a swimming pool, among other amenities.
How much does it cost to stay in a 4-star hotel in Texas Medical Center?
With Expedia's handy search filters, scoring a top deal on a 4-star hotel in Texas Medical Center just got simpler. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best matches your style and budget.

  • Search for the lowest price from AED 1,019

What's the difference between 5-star and 4-star hotels in Texas Medical Center?
Offering a welcoming guest experience and upmarket décor, 4-star hotels are a fantastic option for your Texas Medical Center getaway. These types of stays generally come with loads of handy amenities that make it easy to unpack and unwind — think large beds, bathrobes, pools and restaurants. Or enjoy even more lavishness at a 5-star hotel designed to pamper with high-end perks and amenities. Full-service health clubs, complimentary toiletries and fine dining are typically featured at these swanky properties.