Find 4 Star Hotels in Texas Medical Center, TX from AED 431

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Texas Medical Center 4 Star Hotels

This weekend
Next weekend

Our top choices for Texas Medical Center 4-star hotels

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston
4.0 star property
Downtown Houston
8.6 out of 10, Excellent, (4,124 reviews)
"Great location, friendly attentive staff."
United States
Rose
The price is AED 368
AED 431 total
includes taxes & fees
18 May - 19 May
Club Quarters Hotel Downtown, Houston

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
Greater Uptown
8.4 out of 10, Very Good, (3,924 reviews)
"Great place to stay"
United States
Jose Luis
The price is AED 514
AED 606 total
includes taxes & fees
29 May - 30 May
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very Good, (1,895 reviews)
"Excellent stay while there for a tournament near NRG. Perfect location. The staff was so wonderful! "
United States
Lindsy
The price is AED 403
AED 475 total
includes taxes & fees
24 May - 25 May
Hilton Houston Plaza/Medical Center

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,810 reviews)
"Great hotel. Very convenient and comfortable for business trips and trips to the medical center. "
United States
Byron
The price is AED 543
AED 635 total
includes taxes & fees
31 May - 1 Jun
Blossom Hotel Houston, Curio Collection by Hilton

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1,006 reviews)
"Wonderful and helpful staff!"
United States
Ashlee
The price is AED 741
AED 1,033 total
includes taxes & fees
25 May - 26 May
Hotel Zaza Houston Museum District

The Whitehall Houston

The Whitehall Houston
4.0 star property
Downtown Houston
8.6 out of 10, Excellent, (2,165 reviews)
"Great place to stay for work meetings. Close to where I need to be. Great place to stay. "
United States
Jacob
The price is AED 525
AED 615 total
includes taxes & fees
17 May - 18 May
The Whitehall Houston

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria
8.6 out of 10, Excellent, (1,865 reviews)
"Would stay here again. Very central, clean & excellent service. "
United States
Saamia
The price is AED 449
AED 525 total
includes taxes & fees
3 May - 4 May
The Royal Sonesta Houston Galleria

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,329 reviews)
"We really enjoyed our stay here, I think this will be our go to spot when we just want to get away from the house for the weekend."
United States
LINDA
The price is AED 591
AED 696 total
includes taxes & fees
24 May - 25 May
Hyatt Regency Houston/Galleria

DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
Greenway Plaza-Upper Kirby
8.4 out of 10, Very Good, (1,564 reviews)
"The room was clean, the location near Lakewood is why I stay here. "
United States
Cathy
The price is AED 424
AED 496 total
includes taxes & fees
9 May - 10 May
DoubleTree by Hilton Hotel Houston - Greenway Plaza

Omni Houston Hotel

Omni Houston Hotel
4.0 star property
Greater Uptown
9.2 out of 10, Wonderful, (1,002 reviews)
"Great place to stay in Houston "
United States
Rakeshkumar
The price is AED 621
AED 737 total
includes taxes & fees
10 May - 11 May
Omni Houston Hotel

The Westin Galleria Houston

The Westin Galleria Houston
4.5 star property
The Galleria
9.0 out of 10, Wonderful, (1,003 reviews)
"Great place to stay"
United States
David
The price is AED 777
AED 1,028 total
includes taxes & fees
23 May - 24 May
The Westin Galleria Houston

The Moran CITYCENTRE

The Moran CITYCENTRE
4.0 star property
Memorial
9.0 out of 10, Wonderful, (1,008 reviews)
"Excellent stay "
United States
Anthony
The price is AED 673
AED 897 total
includes taxes & fees
21 May - 22 May
The Moran CITYCENTRE

Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel
4.0 star property
Downtown Houston
9.2 out of 10, Wonderful, (1,498 reviews)
"Everything was fantastic and would absolutely stay here again."
United States
jonathan scott
The price is AED 485
AED 579 total
includes taxes & fees
17 May - 18 May
Magnolia Hotel Houston, A Tribute Portfolio Hotel

Marriott Marquis Houston

Marriott Marquis Houston
4.0 star property
Downtown Houston
9.0 out of 10, Wonderful, (1,107 reviews)
"Beautiful hotel, very nice staff"
United States
Crystal
The price is AED 907
AED 1,166 total
includes taxes & fees
21 May - 22 May
Marriott Marquis Houston

Houston Marriott Westchase

Houston Marriott Westchase
4.0 star property
Westchase
8.4 out of 10, Very Good, (1,010 reviews)
"it was a good stay, recommended. "
United States
Yanwen
The price is AED 379
AED 445 total
includes taxes & fees
16 May - 17 May
Houston Marriott Westchase

Grand Tuscany Hotel

Grand Tuscany Hotel
4.0 star property
Fairbanks
7.6 out of 10, Good, (24 reviews)
"Beautiful hotel. "
United States
Jiayou
The price is AED 393
AED 460 total
includes taxes & fees
7 May - 8 May
Grand Tuscany Hotel

The Westin Oaks Houston at the Galleria

The Westin Oaks Houston at the Galleria
4.0 star property
The Galleria
9.2 out of 10, Wonderful, (1,001 reviews)
"Great location in the Galeria. Clean and ample rooms."
United States
Hernan
The price is AED 777
AED 1,028 total
includes taxes & fees
22 May - 23 May
The Westin Oaks Houston at the Galleria

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,003 reviews)
"Beautiful property "
United States
Halona
The price is AED 613
AED 791 total
includes taxes & fees
30 May - 31 May
InterContinental Houston by IHG

Hotel ZaZa Houston Memorial City

Hotel ZaZa Houston Memorial City
4.0 star property
Memorial
9.4 out of 10, Exceptional, (1,002 reviews)
"Beautiful hotel "
United States
Anna
The price is AED 851
AED 1,165 total
includes taxes & fees
14 May - 15 May
Hotel ZaZa Houston Memorial City

The Laura Hotel, Houston Downtown, Autograph Collection

The Laura Hotel, Houston Downtown, Autograph Collection
4.5 star property
Downtown Houston
9.0 out of 10, Wonderful, (1,094 reviews)
"Amazing staycation"
United States
Charlsa
The price is AED 657
AED 886 total
includes taxes & fees
8 May - 9 May
The Laura Hotel, Houston Downtown, Autograph Collection
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Texas Medical Center.
Still don't see what you're looking for?
See all properties in Texas Medical Center.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Texas Medical Center Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Texas Medical Center?
Blossom Hotel Houston and DoubleTree by Hilton Houston Medical Center Hotel & Suites are two highly recommended getaways located in or near Texas Medical Center. Both have a 4-star rating and promise high-end comfort alongside an unrivaled guest experience. Check in to the first and get access to designer toiletries and a rooftop terrace. The second features premium bedding and a swimming pool, among other amenities.
How much does it cost to stay in a 4-star hotel in Texas Medical Center?
With Expedia's handy search filters, scoring a top deal on a 4-star hotel in Texas Medical Center just got simpler. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best matches your style and budget.

  • Search for the lowest price from AED 753

What's the difference between 5-star and 4-star hotels in Texas Medical Center?
Offering a welcoming guest experience and upmarket décor, 4-star hotels are a fantastic option for your Texas Medical Center getaway. These types of stays generally come with loads of handy amenities that make it easy to unpack and unwind — think large beds, bathrobes, pools and restaurants. Or enjoy even more lavishness at a 5-star hotel designed to pamper with high-end perks and amenities. Full-service health clubs, complimentary toiletries and fine dining are typically featured at these swanky properties.