A large eye sculpture in a park surrounded by trees.

Find 5 Star Hotels in Northeast Missouri, MO from AED 508

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Check availability on Northeast Missouri 5 Star Hotels

Tonight
1 Oct - 2 Oct
Tomorrow
2 Oct - 3 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Northeast Missouri 5-star hotels

An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A bar area with leather seating, a bar counter, and shelves of bottles.

1. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
United States
Kennedy
AED 2,127
AED 2,483 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Northeast Missouri.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO
AED 434
AED 508 total
15 Oct - 16 Oct
includes taxes & fees
8.4/10 Very Good! (1,189 reviews)
Renaissance St. Louis Airport Hotel
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
AED 528
AED 635 total
25 Oct - 26 Oct
includes taxes & fees
9/10 Wonderful! (2,130 reviews)
21C Museum Hotel St Louis
The Cheshire

The Cheshire

6300 Clayton Rd Richmond Heights MO
AED 545
AED 647 total
18 Oct - 19 Oct
includes taxes & fees
The Cheshire
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Northeast Missouri?
The amount you pay for a 5-star hotel in Northeast Missouri depends on factors such as when you plan to travel and the length of your stay. An insider tip for bagging the best deal? Use our pricing filters to check out all of the available hotels for your selected dates.
  • Search for the lowest price per night from AED 508
What makes a hotel 5 stars in Northeast Missouri?
From gourmet dining venues and fitness centers to pools and premium bedding, the 5-star experience in Northeast Missouri is all about comfort and luxury. But it requires more than just upscale conveniences to get a 5-star rating. Hotels must also provide superior guest services like in-room massages, on-site dry cleaning and laundry and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Northeast Missouri?
Use Expedia's filters to find a luxury getaway in Northeast Missouri where most of what you need is included. After your initial search, narrow down your results for accommodations that have a rating of 5 stars and are categorized as "All inclusive." The main thing to look forward to at these stays? Pure indulgence and relaxation.

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