A riverside promenade with cafes, trees, and buildings.

Find 5 Star Hotels in Santo Antonio from AED 381

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Check availability on Santo Antonio 5 Star Hotels

Our top choices for Santo Antonio 5-star hotels

A modern hotel with a prominent "EPIC SANA" sign, featuring a grid-like facade and multiple floors.

1. EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,579 reviews)
"Lovely hotel in a great location."
United Kingdom
John
The price is AED 730
AED 806 total
includes taxes & fees
4 Dec - 5 Dec
EPIC SANA Marques Hotel
A spacious lobby with modern chandeliers, a glass staircase, and a seating area.

2. EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,174 reviews)
"Great roof top bar and good. Amazing views of Tagus River !"
United States
Bruce
The price is AED 762
AED 841 total
includes taxes & fees
4 Dec - 5 Dec
EPIC SANA Lisboa Hotel
A modern lobby with a polished floor, a reception desk, and a seating area with a large chandelier.

3. Eurostars Das Letras

Eurostars Das Letras
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent choice the hotel is clean in great location the staff is amazing and very helpful"
United States
Ana
The price is AED 434
AED 493 total
includes taxes & fees
9 Dec - 10 Dec
Eurostars Das Letras
A balcony with wicker furniture, a table with a vase, and a city view.

4. Sofitel Lisbon Liberdade

Sofitel Lisbon Liberdade
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1,005 reviews)
"Great hotel great location"
United States
Bobbie
The price is AED 695
AED 769 total
includes taxes & fees
1 Dec - 2 Dec
Sofitel Lisbon Liberdade
A hotel room with a bed, a desk, a chair, a dining area, and a bathroom with a large mirror.

5. Olivia Lisboa Hotel 5*

Olivia Lisboa Hotel 5*
5.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (352 reviews)
"Thankful for helpful staff; breakfast was delicious; rooms were very clean"
United States
Deborah
The price is AED 556
AED 622 total
includes taxes & fees
13 Nov - 14 Nov
Olivia Lisboa Hotel 5*
A rooftop bar with outdoor seating, including sofas and tables, and a view of the cityscape.

6. Altis Grand Hotel

Altis Grand Hotel
5.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (1,006 reviews)
"The hotel was perfectly located and staff was great."
United States
JoAnn
The price is AED 707
AED 782 total
includes taxes & fees
3 Dec - 4 Dec
Altis Grand Hotel
A rooftop bar with a pool table, bar area, and seating, overlooking a cityscape at dusk.

7. Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Very nice hotel with very nice restaurants!! La cervecería was excellent, you can’t eat fresh fish and Olivier has a great view and good food!! Location was great right on liverdade avenue!! Lots of shops , places to eat and easy to move!! We had a great time and staff were very helpful and always giving suggestions for whatever you needed!! We would go back to this hotel in Lisboa!!"
United States
Julio
The price is AED 1,282
AED 1,392 total
includes taxes & fees
1 Dec - 2 Dec
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
An outdoor dining area with a table and chairs, surrounded by greenery and a modern building in the background.

8. 138 Liberdade Hotel

138 Liberdade Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (922 reviews)
"very nice hotel with very good breakfast buffet clean room and well situated staff welcoming"
Canada
fabienne
The price is AED 814
AED 895 total
includes taxes & fees
30 Nov - 1 Dec
138 Liberdade Hotel
A modern hotel room with a large bed, a chair, a desk, and a view of the city.

9. Iberostar Selection Lisboa

Iberostar Selection Lisboa
5.0 star property
Lisbon City Center
8.8 out of 10, Excellent, (1,003 reviews)
"Really nice hotel with parking and a really nice breakfast.nice bar."
United States
Sigrid
The price is AED 558
AED 624 total
includes taxes & fees
22 Nov - 23 Nov
Iberostar Selection Lisboa
An outdoor seating area with wicker chairs and a large umbrella, surrounded by potted plants and a wooden deck.

10. PortoBay Liberdade

PortoBay Liberdade
5.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (1,007 reviews)
"The staff was very helpful, breakfast was amazing"
United States
luisa
The price is AED 614
AED 684 total
includes taxes & fees
29 Nov - 30 Nov
PortoBay Liberdade
A restaurant with wooden tables and chairs, a bar area, and a large mirror.

11. Browns Avenue Hotel

Browns Avenue Hotel
5.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (447 reviews)
"great place"
United States
Cullen
The price is AED 610
AED 680 total
includes taxes & fees
29 Nov - 30 Nov
Browns Avenue Hotel
A rooftop pool with lounge chairs and umbrellas, surrounded by greenery and buildings.

12. TURIM Boulevard Hotel

TURIM Boulevard Hotel
5.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (524 reviews)
"I like the location as it is at the center of many tours."
United States
Joseph
The price is AED 722
AED 798 total
includes taxes & fees
16 Nov - 17 Nov
TURIM Boulevard Hotel
A rooftop pool area with a bar and seating, overlooking a cityscape.

13. Memmo Príncipe Real - Design Hotels

Memmo Príncipe Real - Design Hotels
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (362 reviews)
"Comfortable beds, excellent food and drinks! The staff is very helpful and accommodating."
United States
Laura
The price is AED 985
AED 1,076 total
includes taxes & fees
9 Dec - 10 Dec
Memmo Príncipe Real - Design Hotels
A building with ornate architectural details, including carved stonework and a balcony with wrought iron railings.

14. Valverde Lisboa Hotel & Garden - Relais & Châteaux

Valverde Lisboa Hotel & Garden - Relais & Châteaux
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (548 reviews)
"Excellent eestaurant and very kind people"
United States
Alexander
The price is AED 1,320
AED 1,432 total
includes taxes & fees
16 Nov - 17 Nov
Valverde Lisboa Hotel & Garden - Relais & Châteaux
A person in a swimming pool with clear water, surrounded by a tiled floor and a red wall.

15. The Vintage Hotel & Spa - Lisbon

The Vintage Hotel & Spa - Lisbon
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (368 reviews)
"Good location, nice rooms (a bit dark though), and great staff"
Canada
Michael
The price is AED 907
AED 995 total
includes taxes & fees
6 Dec - 7 Dec
The Vintage Hotel & Spa - Lisbon
A multi-story building with classical and modern architectural styles, featuring balconies and large windows.

16. Hang your Hat

Hang your Hat
5.0 star property
Lisbon City Center
Hang your Hat
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santo Antonio.
Locke de Santa Joana

Locke de Santa Joana

18 Rua Camilo Castelo Branco Lisbon
The price is AED 332 per night from Nov 30 to Dec 1
AED 332
AED 385 total
30 Nov - 1 Dec
includes taxes & fees
9.4/10 Exceptional! (2,259 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santo Antonio

Wander through the elegant Avenida da Liberdade, where luxury shops line a boulevard flanked by beautiful gardens and historic squares. Take in panoramic city views at Miradouro de São Pedro de Alcântara before exploring the fascinating collections at the Medeiros e Almeida Museum.

See all hotels in Santo Antonio
A row of historic buildings with ornate balconies and detailed facades.

Top Santo Antonio Hotel Reviews

EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel

8/10 Good
"Breakfast had good variety, Marissa the host was great, attentive and accommodating. Room cleaning staff was attentive although somtimes in consistent with how the room was reset. Fries in the restaurants definitely seem like they are from McDonald's (a positive 😆). The classic cocktails were nice."
Brianna 8-night trip
Posted 1 day ago
EPIC SANA Lisboa Hotel

Frequently asked questions

What are the best 5-star hotels in Santo Antonio?
PortoBay Liberdade is among the leading picks around the Lisbon District neighborhood of Santo Antonio according to reviews by Expedia customers. Altis Grand Hotel and Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world are other 5-star hotels in this area that are favorites among travelers.
How much does it cost to stay in a 5-star hotel in Santo Antonio?
The amount you pay for a 5-star hotel in Santo Antonio can vary based on when you prefer to travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to score the best rate on a high-end stay.

  • Search for the lowest price per night from AED 381

What makes a hotel 5 stars in Santo Antonio?
From fine dining restaurants and all-day gyms to pools and deluxe bedding, the 5-star experience in Santo Antonio is all about indulgence and comfort. But it calls for more than just top-notch amenities to get a 5-star rating. Stays also have to deliver remarkable services like in-room beauty treatments, laundry and dry cleaning and room service any time day or night.

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