Find 5 Star Hotels in St. Louis, MO from AED164

Compare St. Louis 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Terrace/patio
Four Seasons Hotel St Louis
5.0 star property
9.4 out of 10, Exceptional, (911)
"The Four Seasons is a very high end quality hotel. It has great rooms with great beds. The staff was very welcoming and attended to my needs. The only thing I did not like was the noise in the middle of the night from the sirens of police cars and ambulances. It was a bit of a nuances. The place was very clean. I was there for a gala and it was very well put together. The food was very good. The place is very clean. We also visited the Gordon Ramsey restaurant and checked out the other...
The price is AED 1,708
AED 1,997 total
includes taxes & fees
27 May - 28 May
Four Seasons Hotel St Louis
Room
The Ritz-Carlton, St. Louis
5.0 star property
9.2 out of 10, Wonderful, (506)
"Staff, very warming and helpful rooms, clean bright and well maintained"
The price is AED 1,833
AED 2,135 total
includes taxes & fees
27 May - 28 May
The Ritz-Carlton, St. Louis
Living area
Exquisitely Designed Townhome - JZ Vacation Rentals
5.0 star property
10.0 out of 10, Exceptional, (2)
"Am amazing rental space, roomy and well appointed. Suited us perfectly"
The price is AED 687
AED 1,525 total
includes taxes & fees
23 Jun - 24 Jun
Exquisitely Designed Townhome - JZ Vacation Rentals
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Room
Charming Studio in CWE - JZ Vacation Rentals
5.0 star property
8.0 out of 10, Very Good, (1)
Charming Studio in CWE - JZ Vacation Rentals
Living area
Luxurious Townhome Next to Botanical Gardens - JZ Vacation Rentals
5.0 star property
Luxurious Townhome Next to Botanical Gardens - JZ Vacation Rentals
Designer Home in Shaw Left Side - JZ Vacation Rentals
5.0 star property
Designer Home in Shaw Left Side - JZ Vacation Rentals
Dining
Historic Townhome in Central West End - JZ Vacation Rentals
5.0 star property
Historic Townhome in Central West End - JZ Vacation Rentals
Interior
Large & Luxurious 5bdrm 3Ba - JZ Vacation Rentals
5.0 star property
Large & Luxurious 5bdrm 3Ba - JZ Vacation Rentals
Living area
Opulent 5-bedroom Soulard Home - JZ Vacation Rentals
5.0 star property
Opulent 5-bedroom Soulard Home - JZ Vacation Rentals
Living area
Stunning 4 Bedroom Home Near Tilles Park - JZ Vacation Rentals
5.0 star property
Stunning 4 Bedroom Home Near Tilles Park - JZ Vacation Rentals
Private kitchen
Beautiful 3 Bedroom Home in The Grove - JZ Vacation Rentals
5.0 star property
The price is AED 1,752
AED 2,772 total
includes taxes & fees
22 Jun - 23 Jun
Beautiful 3 Bedroom Home in The Grove - JZ Vacation Rentals
Exterior
Chic 4-bed Home Near Attractions - JZ Vacation Rentals
5.0 star property
The price is AED 1,145
AED 2,308 total
includes taxes & fees
23 Jun - 24 Jun
Chic 4-bed Home Near Attractions - JZ Vacation Rentals
Dining
Spacious Reimagined Home in Bevo Mill - JZ Vacation Rentals
5.0 star property
Spacious Reimagined Home in Bevo Mill - JZ Vacation Rentals
Living area
Charming Studio on Cherokee Street - JZ Vacation Rentals
5.0 star property
Charming Studio on Cherokee Street - JZ Vacation Rentals
Living area
Designer Home in Shaw Right Side - JZ Vacation Rentals
5.0 star property
Designer Home in Shaw Right Side - JZ Vacation Rentals
Exterior
Cozy Family Getaway - JZ Vacation Rentals
5.0 star property
Cozy Family Getaway - JZ Vacation Rentals

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Louis.
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO
The price is AED164 per night from May 27 to May 28
AED164
per night
May 27 - May 28
8.4/10 Very Good! (3,021 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in St. Louis?
Boasting first-rate amenities and guest services, our customers rate Four Seasons Hotel St Louis as among the best 5-star hotels in St. Louis. You’ll be immersed in a world of luxury from the moment you step foot into the lobby.
How much does it cost to stay in a 5-star hotel in St. Louis?
There are a range of pricing options for 5-star hotels in St. Louis on Expedia. How much you’ll pay will depend on your vacation dates, trip length and other factors. Compare all of the available accommodations for your chosen dates and make use of our pricing and other filters to find the perfect luxury stay.

  • Search for the lowest price per night from AED164

What makes a hotel 5 stars in St. Louis?
In St. Louis, a hotel needs to offer a certain number of upscale features to be rated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-centric service. You can expect things like concierge services, in-room massages and nightly turn-down services. Some may also offer additional touches like welcome gifts.
Are there any 5-star all-inclusive resorts in St. Louis?
Find a luxury escape that includes your room, meals, drinks and entertainment in St. Louis with the help of Expedia’s filter tool. Search for hotels with a 5-star rating and select the “All inclusive” filter. Make sure you check what’s included in the upfront price. That way, you’re ready to take advantage of all the premium perks when you arrive.
What are the top 5-star spa hotels in St. Louis?
For a rejuvenating stay in St. Louis, it’s hard to beat Four Seasons Hotel St Louis. Book in to this 5-star spa getaway and spend your days pampering yourself with its well-being programs and therapies.
Are there any 5-star vacation rentals in St. Louis?
You won’t find any 5-star vacation rentals in St. Louis on our site, but there are a few other top-rated properties worth checking out. Browse our vacation rentals in St. Louis to discover the perfect place for your stay.
Are there any 5-star hotels in downtown St. Louis?
Spend your break at Four Seasons Hotel St Louis and enjoy being close to the lively action of downtown St. Louis.