Find All South Carolina Midlands Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All South Carolina Midlands Hotels
We have found 3025 South Carolina Midlands Hotels
- Residence Inn Marriott Florence
- Quality Inn & Suites Columbia Harbison
- Courtyard by Marriott Florence
- Home2 Suites by Hilton Florence, SC
- Aloft Columbia Downtown
- Quality Inn Columbia Airport
- Staybridge Suites Florence - Civic Center by IHG
- Quality Inn & Suites Lexington
- Howard Johnson by Wyndham Rock Hill
- Super 8 by Wyndham, Orangeburg
- Comfort Inn Blythewood - North Columbia
- Clarion Inn Columbia Airport
- The Inn at the Crossroads
- Fairfield Inn and Suites by Marriott Columbia
- TRU BY Hilton North Augusta
- Holiday Inn Express Hotel & Suites Blythewood by IHG
- Cambria Hotel Rock Hill - University Center
- SpringHill Suites by Marriott Columbia Downtown/The Vista
- Wingate by Wyndham Columbia/Fort Jackson
- Hampton Inn Columbia Northeast - Fort Jackson Area
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Courtyard by Marriott Columbia Cayce
- Days Inn by Wyndham Florence Near Civic Center
- Hampton Inn Rock Hill
- Holiday Inn Rock Hill by IHG
- MainStay Suites Columbia Harbison
- Motel 6 Rock Hill, SC
- Spark by Hilton Orangeburg
- Woodspring Suites Sumter Near Shaw Afb
- Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG
- SureStay Hotel by Best Western Manning
- avid Hotel Fort Mill - Carowinds Blvd by IHG
- Comfort Suites Florence I-95
- SpringHill Suites by Marriott Florence
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
- Microtel Inn & Suites by Wyndham Florence
- Hampton Inn & Suites Lexington Columbia
- Fairfield Inn by Marriott Orangeburg
- Holiday Inn Express & Suites Lexington by IHG
- Red Roof Inn Columbia East - Ft Jackson
- Hyatt Place Sumter / Downtown
- Holiday Inn Express & Suites Newberry by IHG
- Quality Inn & Suites Florence Civic Center
- Aloft Columbia Harbison
- Fairfield Inn & Suites by Marriott Santee
- Comfort Inn Columbia West
- Comfort Inn & Suites Orangeburg
- Home2 Suites by Hilton Columbia Downtown
- Econo Lodge Rock Hill Northeast
- Tru by Hilton Sumter
- Microtel Inn & Suites by Wyndham Rock Hill/Charlotte Area
- Courtyard by Marriott Charlotte Fort Mill, SC
- Red Roof Inn Rock Hill
- WoodSpring Suites Fort Mill
- Days Inn by Wyndham Orangeburg
- Springhill Suites by Marriott Cheraw
- Hilton Garden Inn Rock Hill
- Ramada Limited Columbia
- Motel 6 Columbia, SC - Fort Jackson Area
- Fairfield Inn by Marriott Hartsville
- Hampton Inn Santee-I-95
- Clarion Inn & Suites Aiken South
- TownePlace Suites Columbia West/Lexington
- Homewood Suites by Hilton Columbia
- Fairfield Inn & Suites by Marriott Florence I-20
- Holiday Inn Santee by IHG
- Motel 6 Florence, SC
- Quality Inn at the Park
- Courtyard by Marriott Ballantyne
- Hilton Garden Inn Columbia Northeast
- Candlewood Suites, Columbia/Ft. Jackson by IHG
- Courtyard by Marriott Rock Hill
- Hampton Inn & Suites Fort Mill
- Comfort Suites Rock Hill Manchester Meadows Area
- Home2 Suites by Hilton Blythewood, SC
- Travelodge by Wyndham Orangeburg
- Fairfield Inn & Suites by Marriott Aiken
- Red Roof Inn Sumter
- Baymont by Wyndham Orangeburg North
- SpringHill Suites by Marriott Orangeburg
- Home2 Suites by Hilton Fort Mill, SC
- Fairfield Inn & Suites Rock Hill
- Hilton Garden Inn Florence
- Best Western Executive Inn
- Best Western Executive Inn & Suites
- Holiday Inn Express & Suites Columbia-I-20 @ Clemson Rd by IHG
- Comfort Inn & Suites Santee
- Holiday Inn Express North Augusta by IHG
- Microtel Inn & Suites by Wyndham Columbia/Fort Jackson N
- WoodSpring Suites Columbia Fort Jackson
- Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG
- Quality Inn & Suites Ft. Jackson Maingate
- Baymont by Wyndham Cheraw
- Extended Stay America Select Suites Columbia Ft. Jackson
- Super 8 by Wyndham Columbia SC / Ft. Jackson
- Hampton Inn Aiken
- Home2 Suites by Hilton Rock Hill
- Home2 Suites by Hilton Columbia Harbison
- Comfort Inn & Suites Rock Hill Northeast