An aerial view of a forested landscape with a river, a parking lot, and a bridge.

Vacation Homes in Anderson County

Compare and save

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
25 Sep - 27 Sep
In two months
6 Nov - 8 Nov
In three months
4 Dec - 6 Dec
In four months
1 Jan - 3 Jan

Our top choices for Anderson County vacation homes

Dining

1. Trail`s Edge Cabin 2Bed, 2Bath next to Table Rock

Trail`s Edge Cabin 2Bed, 2Bath next to Table Rock
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"Very clean, great outdoor area for grilling, s’mores or just relaxing on the porch. Easy check in and communication with the this host was the best I have ever had. Close enough to drive to Clemson for a ball game too. We will definitely book this location again."
United States
John S.
Trail`s Edge Cabin 2Bed, 2Bath next to Table Rock
Terrace/patio

2. Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more

Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Six Mile
9.8 out of 10, Exceptional, (28 reviews)
"Check in was great the host was very helpful in answering all questions. Very clean very satisfied with the stay quiet area away from lake traffic."
United States
CJ L.
The price is AED 1,157
AED 2,866 total
includes taxes & fees
4 Oct - 5 Oct
Lake Keowee Lakefront Cove, Private Dock, Boat Parking, Kayaks & more
Exterior detail

3. Steps Away Downtown Douthit Greenville Getaway!

Steps Away Downtown Douthit Greenville Getaway!
Greenville
8.6 out of 10, Excellent, (11 reviews)
"Absolutely a perfect home!"
United States
Andrea R.
Steps Away Downtown Douthit Greenville Getaway!
Smart TV, fireplace

4. Near great hiking trails and the friendly amenities of downtown Travelers Rest

Near great hiking trails and the friendly amenities of downtown Travelers Rest
Travelers Rest
10.0 out of 10, Exceptional, (61 reviews)
"Very good experience"
United States
Cara L.
Near great hiking trails and the friendly amenities of downtown Travelers Rest
Smart TV, fireplace

5. NEW: Family + Pet-Friendly near Downtown GVL

NEW: Family + Pet-Friendly near Downtown GVL
Greenville
10.0 out of 10, Exceptional, (10 reviews)
"Excellent property. Perfect location and perfect for those traveling with pets. This our go to spot when staying in Greenville. "
United States
Orman S.
NEW: Family + Pet-Friendly near Downtown GVL
Living area

6. Great House In Taylors Just Minutes To Downtown Greenville

Great House In Taylors Just Minutes To Downtown Greenville
Taylors
"Should have been cleaned better! It’s more like a hotel stay in the sense that if you want to feel comfortable at home, this is not the place. If you’re OK with the hotel stay, this is the place!"
United States
Kristina D.
The price is AED 290
AED 602 total
includes taxes & fees
13 Sep - 14 Sep
Great House In Taylors Just Minutes To Downtown Greenville
Interior

7. "Cabin in the Cove" Private waterfront home on beautiful Lake Hartwell

"Cabin in the Cove" Private waterfront home on beautiful Lake Hartwell
Martin
9.8 out of 10, Exceptional, (71 reviews)
"This location is beautiful very family friendly will book again."
United States
jenea r.
"Cabin in the Cove" Private waterfront home on beautiful Lake Hartwell
Terrace/patio

8. Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water
Seneca
9.8 out of 10, Exceptional, (169 reviews)
"Great place with lake front access."
United States
Curt W.
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water
Coffee/tea maker, fridge, microwave, oven

9. NEW Spacious 4-Story 4-bedroom Townhome Retreat in Greenville

NEW Spacious 4-Story 4-bedroom Townhome Retreat in Greenville
Greenville
10.0 out of 10, Exceptional, (16 reviews)
"Wonderful stay! Beautiful property! Owner was a dream to work with and was very easy to communicate with. Quiet area with a 20 min walk to all the shops and restaurants on Main Street."
United States
Andrea L.
The price is AED 1,928
AED 3,277 total
includes taxes & fees
5 Oct - 6 Oct
NEW Spacious 4-Story 4-bedroom Townhome Retreat in Greenville
Outdoor dining

10. Resort Access - Lake - Pools -Pickleball - Gym. Spacious townhome for groups

Resort Access - Lake - Pools -Pickleball - Gym. Spacious townhome for groups
Salem
10.0 out of 10, Exceptional, (38 reviews)
"Great stay! Hosts were so welcoming and easy to work with. Everything was great."
United States
Marika J.
Resort Access - Lake - Pools -Pickleball - Gym. Spacious townhome for groups
Dining

11. Private, pet-friendly adorable getaway mins to downtown

Private, pet-friendly adorable getaway mins to downtown
Greenville
9.8 out of 10, Exceptional, (131 reviews)
"A great getaway! Close enough to Clemson and close to Greenville. Perfect for our family."
United States
Deanna C.
Private, pet-friendly adorable getaway mins to downtown
Terrace/patio

12. Charming pet-friendly Greenville house with mountain setting and fenced yard

Charming pet-friendly Greenville house with mountain setting and fenced yard
Greenville
10.0 out of 10, Exceptional, (31 reviews)
"This house was so adorable and the area around it was just as beautiful! We loved the porch swing and its proximity to Paris Mountain State Park. "
United States
Michelle Y.
Charming pet-friendly Greenville house with mountain setting and fenced yard
Coffee/tea maker, fridge, microwave, oven

13. The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (106 reviews)
"Fully equipped, comfortable beds…everything to make for an enjoyable stay. "
United States
Ron E.
The price is AED 271
AED 819 total
includes taxes & fees
8 Sep - 9 Sep
The Blue Bungalow by Unity Park - Newly Renovated
Microwave, oven, stovetop, dishwasher

14. Delightful 2-bedroom house with AC in charming Easley

Delightful 2-bedroom house with AC in charming Easley
Easley
9.8 out of 10, Exceptional, (17 reviews)
"Great location. Clean."
United States
Donald C.
Delightful 2-bedroom house with AC in charming Easley
Exterior

15. Just updated! Downtown Greer house. Walk to downtown shops. Fenced in backyard

Just updated! Downtown Greer house. Walk to downtown shops. Fenced in backyard
Greer
10.0 out of 10, Exceptional, (23 reviews)
"The house was clean and had everything we needed for our stay. "
United States
Anneice T.
Just updated! Downtown Greer house. Walk to downtown shops. Fenced in backyard
3 bedrooms, iron/ironing board, WiFi (free), bed sheets

16. Highland Hideaway 3BD-2BTH, Gameday Stadium-walkable, 82"TV/Pool Table/Firepit

Highland Hideaway 3BD-2BTH, Gameday Stadium-walkable, 82"TV/Pool Table/Firepit
Clemson
Highland Hideaway 3BD-2BTH, Gameday Stadium-walkable, 82"TV/Pool Table/Firepit
Property grounds

17. 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!
Seneca
9.8 out of 10, Exceptional, (388 reviews)
"Nice place with beautiful view!"
United States
roman s.
4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!
Outdoor dining

18. Cozy 2-bedroom house on Lake Keowee with private dock

Cozy 2-bedroom house on Lake Keowee with private dock
West Union
10.0 out of 10, Exceptional, (20 reviews)
"We thoroughly enjoyed our stay. The condo was exceptionally clean, comfortable, and felt very well cared for. The two-bedroom layout worked great for our family, and it had everything we needed for a relaxing few days at the lake.The views were beautiful, and we spent a lot of time enjoying the peaceful water and dock area. It’s a great spot for anyone who enjoys being on the lake.The only thing future guests should know is that the walk down to the dock is fairly steep. It wasn’t a problem for...
United States
Michael T.
Cozy 2-bedroom house on Lake Keowee with private dock
Outdoor dining

19. 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
Seneca
9.8 out of 10, Exceptional, (172 reviews)
"Exactly what we wanted. All around fantastic stay."
United States
Barbara A.
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
Property grounds

20. Beautiful large family home with dock on Lake Keowee!

Beautiful large family home with dock on Lake Keowee!
Seneca
9.8 out of 10, Exceptional, (131 reviews)
"Exactly as advertised. Host instructions were thorough and we enjoyed the trip without any need for contact. Beautiful area and home."
United States
Tom K.
Beautiful large family home with dock on Lake Keowee!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Anderson County Hotel Reviews

Hotel Hartness

Hotel Hartness

10/10 Excellent
"This property was amazing, comfortable and with every amenity needed to be happy. Will definitely return to this unique property."
Elizabeth 1-night trip
Posted 8 hours ago
Hotel Hartness

Explore a world of travel with Expedia