A calm river with boats, lush greenery, and a clear blue sky.

Find Resorts & Hotels with Spas in Big Pine Key, FL

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Check availability on Big Pine Key Resorts & Hotels with Spas

This weekend
26 Jun - 28 Jun
Next weekend
3 Jul - 5 Jul

Our top choices for Big Pine Key hotels with a spa

Reception

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.6 out of 10, Excellent, (1,163 reviews)
  • cleanliness
    Rejuvenate at this waterfront resort's luxurious Ocean Spa with specialized massages in serene rooms.
The price is AED 483
AED 682 total
includes taxes & fees
1 Jul - 2 Jul
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Couples treatment rooms, body treatments, aromatherapy

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,175 reviews)
  • cleanliness
    Restore serenity at this beachfront hotel with 5 tranquil spa treatment rooms and multiple outdoor pools overlooking stunning ocean views.
The price is AED 809
AED 1,131 total
includes taxes & fees
6 Jul - 7 Jul
Isla Bella Beach Resort & Spa
3 outdoor pools, sun loungers

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Rejuvenate your spirit at this waterfront sanctuary where serene spa treatments complement 3 sparkling pools.
The price is AED 856
AED 1,200 total
includes taxes & fees
29 Jun - 30 Jun
Tranquility Bay Beachfront Hotel and Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Big Pine Key

Pool
Breakfast included

Top Big Pine Key Hotel Reviews

Banana Bay Resort & Marina

Banana Bay Resort & Marina

8/10 Good
"Room was great! Staff was friendly, pool area was taken over by loud guests to say the least and due to no other swimming areas available at the property that was a negative for us. Breakfast could use a few more options, but overall a great stay!"
Nayara 2-night trip
Posted 1 day ago
Banana Bay Resort & Marina

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Frequently asked questions

Looking for a spa hotel in Big Pine Key?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the beaches in Big Pine Key - worth a picture or two! Be sure to enjoy activities like kayaking and snorkeling during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation.
What's there to see and do in Big Pine Key?
Enjoy all that Big Pine Key has to offer and visit Florida Keys Beaches, Calusa Beach, and Bahia Honda State Park. If you have extra time while you're in the area, you might want to see Big Pine Key Flea Market and Blue Hole.
What is a Big Pine Key spa hotel?
Spa hotels in Big Pine Key provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.