Find Resorts & Hotels with Spas in Big Pine Key, FL

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Check availability on Big Pine Key Resorts & Hotels with Spas

Tonight
5 Mar - 6 Mar
Tomorrow
6 Mar - 7 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

Our top choices for Big Pine Key hotels with a spa

Couples treatment rooms, body treatments, aromatherapy

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,100 reviews)
"great resort "
United States
Niki
The price is AED 1,907
AED 2,404 total
includes taxes & fees
15 Mar - 16 Mar
Isla Bella Beach Resort & Spa
Sports facility

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,215 reviews)
"Beautiful resort, only was there for one night, will be back for a longer stay. "
United States
Denise
The price is AED 1,314
AED 1,617 total
includes taxes & fees
5 Apr - 6 Apr
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
3 outdoor pools, sun loungers

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,003 reviews)
"The customer service and hospitality was exceptional. "
United States
Janine
The price is AED 2,054
AED 2,561 total
includes taxes & fees
13 Mar - 14 Mar
Tranquility Bay Beachfront Hotel and Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Big Pine Key

Pool
Breakfast included

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Top Big Pine Key Hotel Reviews

Banana Bay Resort & Marina

Banana Bay Resort & Marina

8/10 Good
"we did not have a waterview room. Air conditioner was a bit noisy. It was chilly when we were in town so thankfully the ceiling fan was enough for us."
anne 4-night trip
Posted 3 days ago
Banana Bay Resort & Marina

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Frequently asked questions

Looking for a spa hotel in Big Pine Key?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the beaches in Big Pine Key - worth a picture or two! Be sure to enjoy activities like kayaking and snorkeling during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation.
What's there to see and do in Big Pine Key?
Enjoy all that Big Pine Key has to offer and visit Calusa Beach, Bahia Honda State Park, and Florida Keys Beaches. If you have extra time while you're in the area, you might want to see Big Pine Key Flea Market and Cook Island.
What is a Big Pine Key spa hotel?
Spa hotels in Big Pine Key provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.