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Check prices for these dates

In two weeks
17 Oct - 19 Oct
In two months
28 Nov - 30 Nov
In three months
26 Dec - 28 Dec
In four months
23 Jan - 25 Jan

Vacation Homes in Byron

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
Fridge, microwave, oven, stovetop

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom

10.0 out of 10, Exceptional, (63)
"Wonderful quiet neighborhood. Plenty of room for multiple family members. Clean and quaint. Wonderful host!"
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Fridge, microwave, oven, stovetop

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (98)
"perfect location perfect house. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!
Property grounds

Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!

9.8 out of 10, Exceptional, (7)
"Attended Viola Gopher Count. Great place. Great location."
Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!
Century Cottage-PERFECT for Mayo & downtown visitors!
Outdoor dining

Century Cottage-PERFECT for Mayo & downtown visitors!

10.0 out of 10, Exceptional, (127)
"I love staying at the Cottage! Its my go-to spot when i travel to Rochester. "
Century Cottage-PERFECT for Mayo & downtown visitors!
Single Level Living with Comfortable Recliners
Fridge, microwave, oven, stovetop

Single Level Living with Comfortable Recliners

10.0 out of 10, Exceptional, (36)
"It was really nice and clean"
Single Level Living with Comfortable Recliners
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Dining

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

10.0 out of 10, Exceptional, (4)
"We stayed here for a quick night before heading into WI to visit family! We loved how cozy and pet friendly it was! We will stay again! "
The price is AED 547
AED 723 total
includes taxes & fees
17 Oct - 18 Oct
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Mynte House l Modern 4BR Near Mayo, Fast WiFi, Parking, Office, Bidet
Fridge, microwave, oven, stovetop

Mynte House l Modern 4BR Near Mayo, Fast WiFi, Parking, Office, Bidet

9.2 out of 10, Wonderful, (12)
"This is a beautiful property, exactly as pictured. Extremely clean, beds were very comfortable, great location. "
Mynte House l Modern 4BR Near Mayo, Fast WiFi, Parking, Office, Bidet
Entertainment for the whole family. Sleeps up to 10.
Outdoor dining

Entertainment for the whole family. Sleeps up to 10.

10.0 out of 10, Exceptional, (12)
"Everything was just as pictured and described except only half of the back lawn had been mowed and what was mowed seemed like it isn’t done regularly and looked like a hayfield"
Entertainment for the whole family. Sleeps up to 10.
Magical Nest Hideaway
Exterior

Magical Nest Hideaway

10.0 out of 10, Exceptional, (129)
"Stayed a couple days. Nice location and friendly owners. "
Magical Nest Hideaway
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Fridge, microwave, oven, stovetop

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

10.0 out of 10, Exceptional, (42)
"The house was as described! Pictures do the house justice and I can say for the first time in a couple VRBO stays that the beds were comfortable. "
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Lovely 2 BR 2BA, Close to Mayo and trails
Outdoor dining

Lovely 2 BR 2BA, Close to Mayo and trails

2.0 star property
9.6 out of 10, Exceptional, (5)
"We came to Rochester for the weekend for a convention. This property was more than we expected. Super nice! Host was great! Loved the cookies, too. "
Lovely 2 BR 2BA, Close to Mayo and trails
The Best of Southwest Rochester, MN
Living area

The Best of Southwest Rochester, MN

10.0 out of 10, Exceptional, (1)
"The house was lovely and impeccably clean and well stocked with essentials and bonus coffee, snacks and candies. Check in was clear and easy. Thank you, Sarah!"
The Best of Southwest Rochester, MN
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Interior

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

9.0 out of 10, Wonderful, (18)
"It was a great day. Probably was cleaning. Beds were comfortable. Really enjoyed it."
The price is AED 184
AED 753 total
includes taxes & fees
3 Oct - 4 Oct
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Outdoor dining

Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

9.6 out of 10, Exceptional, (18)
"Everything was excellent! Super happy"
The price is AED 545
AED 1,228 total
includes taxes & fees
14 Oct - 15 Oct
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)
3 bedrooms, iron/ironing board, WiFi, bed sheets

New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)

9.8 out of 10, Exceptional, (43)
"Communication was fantastic, lovely house! "
New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)
SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO
Interior

SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO

SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Fridge, microwave, oven, stovetop

Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic

10.0 out of 10, Exceptional, (37)
"Beautiful house in Rochester. Comfortable and clean with a very “at home” vibe. Broc was fabulous to work with and was always very quick to respond. We loved staying here!! "
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Recliners. Single Level Living. Walk in shower.
Fridge, microwave, oven, stovetop

Recliners. Single Level Living. Walk in shower.

10.0 out of 10, Exceptional, (23)
"Very clean! Beds were comfortable! Host was very responsive! We will definitely stay here again! "
Recliners. Single Level Living. Walk in shower.
One Level Retreat 10 min to Mayo: Power recliner, Jacuzzi tub, Deck w Grill
Fridge, microwave, oven, stovetop

One Level Retreat 10 min to Mayo: Power recliner, Jacuzzi tub, Deck w Grill

10.0 out of 10, Exceptional, (5)
"In town for family member's surgery. The house was so comfortable and quiet for her recovery. We all wish we could have stayed longer! We enjoyed the deck and all the wildlife. House is very organized and Bridget is so kind and welcoming. Definitely will recommend if anyone we know is traveling to the area!"
One Level Retreat 10 min to Mayo: Power recliner, Jacuzzi tub, Deck w Grill
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Fridge, microwave, oven, stovetop

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

9.8 out of 10, Exceptional, (66)
"Swimming pool construction crew in town to install a new concrete pool."
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Byron Hotel Reviews

Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"There’s a lot of street work in progress around the hotel right now; but the inconvenience is manageable. You can’t beat the price and convenience for proximity and accessibility to the Mayo Clinic. "
T 1-night trip
Posted 15 hours ago
Kahler Grand Hotel