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Find Casinos in Cape Girardeau, MO

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Pick from 8 Cape Girardeau Casinos and compare room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, (1000)
"Very nice and clean with great location and excellent staff. "
The price is AED 430
AED 477 total
includes taxes & fees
27 Jun - 28 Jun
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Inn & Suites Cape Girardeau
Exterior
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (789)
"The hotel is located in an area with shopping and restaurants are in walking distance. It is very clean and quiet. "
Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1002)
"Fairly quiet, clean property real nice staff very helpful"
The price is AED 195
AED 220 total
includes taxes & fees
23 Jun - 24 Jun
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau West
Exterior
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1000)
"We have stayed here several times visiting our son at SEMO. Clean and friendly staff. Close to shopping and restaurants."
The price is AED 225
AED 254 total
includes taxes & fees
25 Jun - 26 Jun
Pear Tree Inn Cape Girardeau West
Auburn Place Hotel And Suites
Indoor pool
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1002)
"When we first checked in, Karen at the front desk was AWESOME! There were cookies and milk and she directed us about the amenities of the hotel as well as the best place to park based on our room location. The room itself, while small and had some dated fixtures/doors, was very clean. I was thoroughly impressed! We went to the pool area that seemed busy and they were out of towels but that was okay. We used the dollar-to-coin change machine and played a few games of pool in the game area,...
The price is AED 241
AED 271 total
includes taxes & fees
1 Jul - 2 Jul
Auburn Place Hotel And Suites
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (636)
"Daughter had grandbaby #4 ... I always like to stay here. Staff is amazing. This location is super easy to get to right off highway to shopping and restaurants. Super quiet. "
The price is AED 292
AED 345 total
includes taxes & fees
23 Jun - 24 Jun
Candlewood Suites Cape Girardeau, an IHG Hotel
Quality Inn
Exterior
Quality Inn
2.5 star property
7.0 out of 10, Good, (474)
"Remote to TV didn't work. Replaced batteries, still didn't work. Had to unplug TV to turn it off."
The price is AED 250
AED 282 total
includes taxes & fees
23 Jun - 24 Jun
Quality Inn
Town House Inn Cape Giradreau
Exterior
Town House Inn Cape Giradreau
2.5 star property
6.0 out of 10, (142)
"Nothing like the one in jackson. I stayed at the townhouse inn in jackson mo then the one in cape girardeau. The one in jackson 10 stars the one in cape 2 stars so its woryh the 5 min drive "
The price is AED 273
AED 319 total
includes taxes & fees
24 Jun - 25 Jun
Town House Inn Cape Giradreau
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Searching for casino hotels in Cape Girardeau?
Hoping to win big in Cape Girardeau? You’re in luck, because you’ll find Isle Casino Cape Girardeau here, not to mention lots more to see and do. Visitors enjoy the riverfront, shopping, and dining options.
How many hotels that are good for gaming can I expect to find in Cape Girardeau?
Hit the casinos and have a good night’s sleep at one of Expedia’s 58 casino hotels in Cape Girardeau.
When should I take my casino trip to Cape Girardeau?
You might spend a lot of your vacation inside, but if you’re planning to venture beyond the casino, taking a look at local weather data can help you. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.
What is there to do in Cape Girardeau?
Cape Girardeau is known for its historic sites, offering you opportunities to enjoy the local culture. Some attractions to visit in the area are Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. For more to see and do, you can plan to visit Riverfront Bridge Park and Show Me Center.
What are my transportation options for my casino getaway to Cape Girardeau?
Here are some transportation options in Cape Girardeau: You can arrange a flight to the closest airport, which is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), situated 6 mi (9.7 km) from the city center. If you’d like to explore around the area, you may want to rent a car for your trip.

Recent reviews of Cape Girardeau hotels
Expedia verified reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

5/5 Excellent
"Very nice and clean with great location and excellent staff. "
A verified traveler stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Posted 3 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel