Find Resorts & Hotels with Spas in Clayton, MO

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Pick from 6 Clayton Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Exterior
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
9.0 out of 10, Wonderful, (732)
"Great hotel "
The price is AED 635
AED 746 total
includes taxes & fees
29 Jun - 30 Jun
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
The Ritz-Carlton, St. Louis
Room
The Ritz-Carlton, St. Louis
5.0 star property
9.2 out of 10, Wonderful, (510)
"Lovely experience "
The price is AED 1,723
AED 2,007 total
includes taxes & fees
20 Jul - 21 Jul
The Ritz-Carlton, St. Louis
Le Méridien St. Louis Clayton
Room
Le Méridien St. Louis Clayton
4.0 star property
8.8 out of 10, Excellent, (483)
"Nice property "
The price is AED 621
AED 711 total
includes taxes & fees
30 Jun - 1 Jul
Le Méridien St. Louis Clayton
Clayton Plaza Hotel & Extended Stay
Exterior
Clayton Plaza Hotel & Extended Stay
3.5 star property
9.0 out of 10, Wonderful, (2881)
"It’s our second time staying there, so it’s pretty nice."
The price is AED 384
AED 434 total
includes taxes & fees
30 Jun - 1 Jul
Clayton Plaza Hotel & Extended Stay
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Property entrance
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
8.4 out of 10, Very Good, (544)
"Such a cute hotel! Older feeling with new upgrades "
The price is AED 496
AED 568 total
includes taxes & fees
1 Jul - 2 Jul
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Residence Inn By Marriott St. Louis Clayton
Exterior
Residence Inn By Marriott St. Louis Clayton
3.0 star property
9.2 out of 10, Wonderful, (96)
"Hotel was very clean and had everything we needed. The gym was well equipped and even had some machines in addition to free weights and cardio equipment. "
The price is AED 569
AED 669 total
includes taxes & fees
1 Jul - 2 Jul
Residence Inn By Marriott St. Louis Clayton
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Living room of apartment offers comfort & a sleeper sofa.
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
9.4 out of 10, Exceptional, (3)
"We thoroughly enjoyed our stay. The rooftop views are tremendous!"
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
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See all available properties in Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Looking for a spa hotel in Clayton?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Clayton. Be sure to pay a visit to the museums during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Clayton?
Among Expedia’s 10 accommodation options in Clayton, there are 3 spa hotels.
What's there to see and do in Clayton?
Enjoy all that Clayton has to offer when you visit Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Zoo, and St. Louis Union Station. If you have some spare time during your trip, you might want to check out Busch Stadium and Gateway Arch.
What is a Clayton spa hotel?
Spa hotels in Clayton provide lodging and have an on-site spa offering services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

Recent reviews of Clayton hotels
Expedia verified reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

5/5 Excellent
"Room had been recently updated. Bathroom/Shower was excellent. Ongoing upgrades will better the facility. Lobby need repairs at ceiling and upholstery needs cleaning."
A verified traveler stayed at Clayton Plaza Hotel & Extended Stay
Posted 1 day ago
Clayton Plaza Hotel & Extended Stay