Find Business Hotels in Downtown Des Moines, IA

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown Des Moines Business Hotels

Our top choices for Downtown Des Moines business-friendly hotels

Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Downtown Des Moines
9.4 out of 10, Exceptional, (1000)
"The check in lady was a grouchy old bag."
United States
David
The price is AED 316
AED 354 total
includes taxes & fees
29 Dec - 30 Dec
Staybridge Suites Des Moines Downtown by IHG

Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center
2.5 star property
Downtown Des Moines
8.8 out of 10, Excellent, (1007)
"Everything was great! We have stayed here several times and have never had any issues. Staff is great, our room was spotless, in fact, the whole hotel is very neat and clean!! We will stay again!"
United States
Brenda
The price is AED 340
AED 381 total
includes taxes & fees
14 Dec - 15 Dec
Comfort Inn & Suites Event Center

Hilton Des Moines Downtown

Hilton Des Moines Downtown
3.5 star property
Downtown Des Moines
9.0 out of 10, Wonderful, (1000)
"Great place "
United States
Eddie
The price is AED 479
AED 552 total
includes taxes & fees
20 Dec - 21 Dec
Hilton Des Moines Downtown

Des Lux Hotel

Des Lux Hotel
3.5 star property
Downtown Des Moines
9.8 out of 10, Exceptional, (1030)
"Beautiful and clean hotel with very friendly staff."
United States
Scott
The price is AED 546
AED 612 total
includes taxes & fees
11 Dec - 12 Dec
Des Lux Hotel

Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown
3.0 star property
Downtown Des Moines
8.2 out of 10, Very Good, (1008)
"Excellent location, very clean, good breakfast & the staff was great!"
United States
Dawn
The price is AED 371
AED 416 total
includes taxes & fees
15 Dec - 16 Dec
Hyatt Place Des Moines/Downtown

Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines
9.2 out of 10, Wonderful, (963)
"Room is clean great location check in was a breeze"
United States
linda
The price is AED 327
AED 366 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Des Moines Downtown by IHG

Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel
3.5 star property
Downtown Des Moines
8.6 out of 10, Excellent, (1001)
"Great place to stay downtown. "
United States
Wesley
The price is AED 496
AED 555 total
includes taxes & fees
4 Jan - 5 January 2026
Renaissance Des Moines Savery Hotel

Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown
4.0 star property
Downtown Des Moines
9.0 out of 10, Wonderful, (392)
"Clean room, quiet, excellent breakfast. "
United States
Randy
The price is AED 327
AED 366 total
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott Des Moines Downtown

Des Moines Marriott Downtown

Des Moines Marriott Downtown
3.5 star property
Downtown Des Moines
8.8 out of 10, Excellent, (957)
"Great location, clean, easy check in and check out. "
United States
Emily
The price is AED 496
AED 555 total
includes taxes & fees
4 Jan - 5 January 2026
Des Moines Marriott Downtown

AC Hotel Des Moines East Village

AC Hotel Des Moines East Village
3.0 star property
Downtown Des Moines
9.2 out of 10, Wonderful, (405)
"Hotel was clean and staff friendly."
United States
Cathy
The price is AED 555
AED 621 total
includes taxes & fees
19 Dec - 20 Dec
AC Hotel Des Moines East Village
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown Des Moines Hotel Reviews

Explore a world of travel with Expedia