Find Resorts & Hotels with Spas in East Biloxi, MS

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Check prices for these dates

Tonight
5 Nov - 6 Nov
Tomorrow
6 Nov - 7 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for East Biloxi hotels with a spa

A modern spa interior with a prominent sign for 'pure THE PALACE SPA'.

1. Palace Casino Resort

Palace Casino Resort
4.0 star property
Biloxi
9.2 out of 10, Wonderful, (3,154 reviews)
  • cleanliness
    Indulge in luxurious pampering at this bayfront hotel with 5 spa treatment rooms and expert massage services for a rejuvenating escape.
The price is AED 247
AED 276 total
includes taxes & fees
29 Nov - 30 Nov
Palace Casino Resort
A spa room with two beds, a massage table, a sink, and candles.

2. Golden Nugget Biloxi

Golden Nugget Biloxi
4.0 star property
Downtown Biloxi
8.2 out of 10, Very good, (3,479 reviews)
  • cleanliness
    Indulge in ultimate relaxation at this waterfront resort with 9 spa treatment rooms and private outdoor therapy spaces.
The price is AED 131
AED 209 total
includes taxes & fees
24 Nov - 25 Nov
Golden Nugget Biloxi
A well-furnished living room with a sofa, armchairs, a coffee table, and a large abstract painting on the wall.

3. Beau Rivage

Beau Rivage
4.0 star property
Downtown Biloxi
9.4 out of 10, Exceptional, (1,435 reviews)
  • cleanliness
    Revitalize at this waterfront resort with 14 treatment rooms and couples massage suites where deep soaking tubs complement spa journeys.
The price is AED 403
AED 537 total
includes taxes & fees
11 Nov - 12 Nov
Beau Rivage
A spa room with two beds, a large mirror, and a view of palm trees.

4. IP Casino Resort Spa - Biloxi

IP Casino Resort Spa - Biloxi
4.0 star property
Biloxi
8.8 out of 10, Excellent, (5,058 reviews)
  • cleanliness
    Relax at this resort spa with 19 treatment rooms, sauna, and steam room for rejuvenating escape.
The price is AED 257
AED 363 total
includes taxes & fees
1 Dec - 2 Dec
IP Casino Resort Spa - Biloxi
A reception area with a white reception desk, shelves with products, and a wall with a 'Bellissimo' sign.

5. Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination

Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination
4.0 star property
Downtown Biloxi
7.8 out of 10, Good, (1,650 reviews)
  • cleanliness
    Relax in this casino resort's full-service spa offering 12 treatment rooms and a tranquil outdoor pool.
The price is AED 210
AED 321 total
includes taxes & fees
6 Dec - 7 Dec
Harrah's Gulf Coast Hotel & Casino - A Caesars Rewards Destination
A modern lobby with a dark blue wall, a reception desk, a seating area with ottomans, and a decorative wooden partition.

6. OS Hotel

OS Hotel
2.0 star property
Ocean Springs
9.4 out of 10, Exceptional, (199 reviews)
The price is AED 557
AED 618 total
includes taxes & fees
1 Dec - 2 Dec
OS Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in East Biloxi

Pool
Breakfast included

Top East Biloxi Hotel Reviews

A modern spa interior with a prominent sign for 'pure THE PALACE SPA'.
Palace Casino Resort

Palace Casino Resort

Palace Casino Resort
Biloxi

10/10 Excellent

My family has been coming here for many years and we love it. Always clean, consistent and friendly service.
United States
Kristi
Reviewed June 2, 2025
Palace Casino Resort

Frequently Asked Questions

Looking to vacation at a spa hotel in East Biloxi?

Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Travelers highly recommend the restaurants in East Biloxi. Enjoy the live music and beaches during your vacation. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.

What is the best spa hotel in East Biloxi?

Palace Casino Resort is a top spa hotel featuring 5 restaurants, a casino, a 24-hour fitness center, and an outdoor pool. Spend an afternoon at the spa where you’ll find facials, body scrubs, and Swedish massages. Other popular spa hotels in East Biloxi include Golden Nugget Biloxi and IP Casino Resort Spa - Biloxi.

How many spa hotels are there in East Biloxi?

Among Expedia's 76 accommodation options in East Biloxi, there are 5 spa hotels.

What's there to see and do in East Biloxi?

Enjoy all that East Biloxi has to offer and visit Beach Boulevard, Biloxi Municipal Stadium, and The Salvation Army Kroc Center MS Gulf Coast. If you have a bit of extra time while you’re in the area, you might want to check out Biloxi Little Theater and Lee Street Field.

What is a East Biloxi spa hotel?

Spa hotels in East Biloxi feature full on-site spas offering services like facials and a range of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

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