A modern glass building with a bridge in the background.

Find Business Hotels in Eastern Iowa, IA

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Eastern Iowa Business Hotels

Tonight
15 Oct - 16 Oct
Tomorrow
16 Oct - 17 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Eastern Iowa business-friendly hotels

A living room with a stone fireplace, a black leather sofa, patterned armchairs, and a coffee table with decorative items.
A hotel lobby with a reception desk, seating area, and wall-mounted amenities.
A hotel room with two beds, a sofa, a TV, and a desk.
A hotel room with a large bed, a brown headboard, a white bedside table with a lamp, a blue ottoman, a brown leather sofa, and a separate bathroom with a bathtub.

1. Cornerstone Inn & Suites

Cornerstone Inn & Suites
Oelwein
United States
Chelsey Rae
AED 345
AED 387 total
includes taxes & fees
16 Oct - 17 Oct
Cornerstone Inn & Suites
A restaurant with multiple tables and chairs, a stone fireplace, and framed artwork on the walls.
A cozy lobby with a stone fireplace, a large clock, and comfortable seating.
A vending machine stocked with snacks and drinks, a certificate of training, and a sign indicating the location is a 24-hour marketplace.
A hotel reception area with a Cobblestone Rewards sign, a computer, and a digital screen displaying hotel information.

2. Cobblestone Inn & Suites – Manchester

Cobblestone Inn & Suites – Manchester
Manchester
United States
Paula
AED 343
AED 388 total
includes taxes & fees
11 Nov - 12 Nov
Cobblestone Inn & Suites – Manchester
A Country Inn & Suites building with a covered front porch, outdoor seating, and hanging flower baskets.
A modern living room with a stone fireplace, a blue armchair, a beige sofa with red cushions, and two floor lamps.
A hotel room with a bed, a desk, a chair, a sofa, and a bathroom.
A gym with treadmills, an elliptical, and a weight machine.

3. Country Inn & Suites by Radisson, Decorah, IA

Country Inn & Suites by Radisson, Decorah, IA
Decorah
United States
Ann
AED 409
AED 458 total
includes taxes & fees
15 Nov - 16 Nov
Country Inn & Suites by Radisson, Decorah, IA
A building with a covered entrance, stone pillars, and a paved driveway.
A hotel dining area with multiple tables and chairs, a stone fireplace, and a television mounted on the wall.
A hotel room with a large bed, a separate bathroom with a bathtub, a flat-screen TV, and a desk with a chair.
A playground with slides and picnic tables.

4. Cobblestone Inn & Suites - Monticello

Cobblestone Inn & Suites - Monticello
Monticello
United States
Mark
AED 401
AED 449 total
includes taxes & fees
16 Oct - 17 Oct
Cobblestone Inn & Suites - Monticello
A hotel room with a large bed, a desk with a computer, a TV, and a microwave.
An indoor swimming pool with wooden walls, multiple lounge chairs, and a clear pool area.
Property amenity
A breakfast area with a stone wall, wooden tables and chairs, a coffee station, and a sign for Daybreak Breakfast.

5. Days Inn by Wyndham Evansdale Waterloo

Days Inn by Wyndham Evansdale Waterloo
Evansdale
United States
Daisy
AED 244
AED 273 total
includes taxes & fees
1 Nov - 2 Nov
Days Inn by Wyndham Evansdale Waterloo
A modern hotel building with a prominent sign reading "Hyatt Place."
A modern lobby with a reception desk, seating area, and a bar with shelves of bottles.
An indoor swimming pool with clear views through large windows, lounge chairs, and modern lighting.
A spacious lobby with a modern design, featuring a central reception desk, a staircase, and a seating area with yellow chairs.

6. Hyatt Place Iowa City Downtown

Hyatt Place Iowa City Downtown
Downtown
United States
Mark
AED 404
AED 459 total
includes taxes & fees
25 Oct - 26 Oct
Hyatt Place Iowa City Downtown
A hotel room with two beds, a desk with a computer, a TV, and a window with curtains.
A vending machine with a Pepsi logo, a refrigerated display case with various snacks, and a stand selling branded merchandise.
A covered pavilion with a stone plaque, a picnic area, and a view of the mountains.
A hotel reception area with a coffee machine, a refrigerator, and a self-service beverage dispenser.

7. Comfort Inn & Suites Marquette - Prairie du Chien

Comfort Inn & Suites Marquette - Prairie du Chien
Marquette
United States
Mary
AED 260
AED 292 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn & Suites Marquette - Prairie du Chien
A modern hotel room with a kitchenette, a bed, a sofa, and a TV.
A hotel lobby with a reception desk, seating area, and large windows.
A pool area with a blue chair, metal handrails, and large arched windows.
A reception area with a modern design, featuring a reception desk, a logo on the wall, and a tiled floor.

8. Microtel Inn & Suites by Wyndham Prairie du Chien

Microtel Inn & Suites by Wyndham Prairie du Chien
Southside
United States
Russ
AED 265
AED 296 total
includes taxes & fees
19 Oct - 20 Oct
Microtel Inn & Suites by Wyndham Prairie du Chien
A hotel room with a bed, a desk with a microwave, a television, and artwork on the wall.
A compact hotel room with a kitchenette, a large mirror, a desk with a chair, a sofa, and a patterned rug.
A spacious hotel lobby with multiple seating areas, a central bar, and a visible kitchen area.
An indoor swimming pool with clear glass walls, a tiled deck, and outdoor seating.

9. AmericInn by Wyndham Fairfield

AmericInn by Wyndham Fairfield
Fairfield
United States
Robert
AED 456
AED 511 total
includes taxes & fees
15 Nov - 16 Nov
AmericInn by Wyndham Fairfield
A multi-story hotel with a prominent 'La Quinta' sign, featuring a sun motif. The building has a modern design with brick and stone accents, multiple windows, and a covered entrance area.
A modern hotel room with a bed, a sofa, a desk, and a TV.
A modern kitchen with dark cabinetry, stainless steel appliances, and pendant lighting.
A lobby with a fireplace, seating area, and a large cityscape mural.

10. La Quinta Inn & Suites by Wyndham Coralville Iowa City

La Quinta Inn & Suites by Wyndham Coralville Iowa City
Coralville
United States
Laura
AED 375
AED 420 total
includes taxes & fees
18 Oct - 19 Oct
La Quinta Inn & Suites by Wyndham Coralville Iowa City
View all properties

Top Eastern Iowa Hotel Reviews

Hotel Julien Dubuque

Hotel Julien Dubuque

10/10 Excellent
"Restaurant Caroline’s was excellent"
thomas 1-night trip
Posted 2 hours ago
Hotel Julien Dubuque
Comfort Inn & Suites Davenport - Quad Cities

Comfort Inn & Suites Davenport - Quad Cities

10/10 Excellent
"Clean room, great front desk"
Chris 1-night trip
Posted 3 hours ago
Comfort Inn & Suites Davenport - Quad Cities
Heartland Inn

Heartland Inn

10/10 Excellent
"I needed to print something at midnight. Zack at the front desk went above and beyond to help me without asking."
Thibaud 1-night trip
Posted 5 hours ago
Heartland Inn
Best Western Plus Dubuque Hotel & Conference Center

Best Western Plus Dubuque Hotel & Conference Center

10/10 Excellent
"Wonderful staff!"
Allison 2-night trip
Posted 1 day ago
Best Western Plus Dubuque Hotel & Conference Center
SureStay Plus Hotel by Best Western Coralville Iowa City

SureStay Plus Hotel by Best Western Coralville Iowa City

10/10 Excellent
"Clean, quiet and in a good part of town."
Jacob 1-night trip
Posted 3 days ago
SureStay Plus Hotel by Best Western Coralville Iowa City
American Inn Cedar Rapids South

American Inn Cedar Rapids South

10/10 Excellent
"Helpful clean and quiet would come again"
Anthony 1-night trip
Posted 4 days ago
American Inn Cedar Rapids South
Doubletree by Hilton Cedar Rapids Convention Complex

Doubletree by Hilton Cedar Rapids Convention Complex

10/10 Excellent
"phenomenal experience. Great property close to restaurants and night life. Clean and a helpful staff. Thoroughly enjoyed the stay."
Martin 2-night trip
Posted 8 days ago
Doubletree by Hilton Cedar Rapids Convention Complex

Explore a world of travel with Expedia