Find Boutique Hotels in Florence, SC

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Check availability on Florence Boutique Hotels

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Florence Boutique Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Florence

Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1158)
"Enjoyed our stay there. "
United States
Cathy
The price is AED 369
AED 413 total
includes taxes & fees
4 Jan - 5 January 2026
Comfort Inn & Suites Florence Center Area
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property
Florence
8.8 out of 10, Excellent, (2476)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is AED 228
AED 255 total
includes taxes & fees
7 Dec - 8 Dec
Howard Johnson by Wyndham Florence
Indoor pool
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property
Florence
9.2 out of 10, Wonderful, (1002)
"Very good breakfast & convenient location"
United States
Diedre
The price is AED 404
AED 452 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Exterior
The Inn at the Crossroads

The Inn at the Crossroads

2.0 star property
Lake City
9.4 out of 10, Exceptional, (824)
"Awesome hotel stay "
United States
Jerry
The price is AED 438
AED 491 total
includes taxes & fees
6 Jan - 7 January 2026
The Inn at the Crossroads
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property
Florence
9.0 out of 10, Wonderful, (2192)
"Breakfast was great, room very clean ."
United States
Leann
The price is AED 345
AED 387 total
includes taxes & fees
7 Dec - 8 Dec
Park Inn by Radisson Florence, SC
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
Florence
9.4 out of 10, Exceptional, (922)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is AED 496
AED 555 total
includes taxes & fees
14 Dec - 15 Dec
Staybridge Suites Florence - Civic Center by IHG
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 star property
Florence
9.0 out of 10, Wonderful, (809)
"Clean room, courteous staff and easy access to and from highway."
United States
Joe
The price is AED 391
AED 438 total
includes taxes & fees
6 Jan - 7 January 2026
Hampton Inn & Suites Florence-North-I-95
Front of property - evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property
Florence
8.8 out of 10, Excellent, (1002)
"Great stay"
United States
Michaelle
The price is AED 367
AED 411 total
includes taxes & fees
15 Dec - 16 Dec
Hyatt Place Florence Downtown
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

2.5 star property
Florence
9.0 out of 10, Wonderful, (547)
"Good breakfast and room service "
United States
Indira
The price is AED 394
AED 441 total
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott Florence I-20
Exterior
Hilton Garden Inn Florence

Hilton Garden Inn Florence

2.5 star property
Florence
8.4 out of 10, Very Good, (251)
"Restaurants, shopping (the Mall) was right across the street. Stay was very friendly and helpful."
United States
Janie
The price is AED 365
AED 409 total
includes taxes & fees
14 Dec - 15 Dec
Hilton Garden Inn Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florence Hotel Reviews

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Frequently asked questions

What's there to see and do in Florence?
The shopping and restaurants are just some of the things to enjoy while you're in the area. Florence Museum, Florence National Cemetery, and Dr. Eddie Floyd Tennis Center are some of the local sights worth visiting. While you're here, you might also like to explore more of the area and take in additional sights like Magnolia Mall, Florence Civic Center, and Palmetto Shores Lake.
What kind of weather should I plan for when I travel to Florence?
Having a good idea of the weather in Florence will help you enjoy your stay to the fullest. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's the best way to get to my boutique hotel in Florence?
You have a few options for getting to Florence. The nearest major airport is Florence, SC (FLO-Florence Regional), which is located 2.3 mi (3.7 km) from the heart of the city. If you want to explore the larger area, hop on a train at Florence Station.