Find Boutique Hotels in Greenville, SC

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Greenville Boutique Hotels

Tonight
5 Oct - 6 Oct
Tomorrow
6 Oct - 7 Oct
Next weekend
10 Oct - 12 Oct
In two weeks
17 Oct - 19 Oct

Top Greenville Boutique Hotels

Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is AED 1,686
AED 1,855 total
includes taxes & fees
29 Oct - 30 Oct
Hotel Domestique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Greenville Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's there to see and do in Greenville?
The shopping, waterfalls, and sporting events are just some of the things to enjoy while you're in the area. Activities and attractions to experience around Greenville include The Peace Center, Greenville County Museum of Art, and Bob Jones University Museum and Gallery. For even more to see and do, make a stop at The Children's Museum of the Upstate, Bon Secours Wellness Arena, and Greenville Zoo.
What kind of weather should I plan for when I travel to Greenville?
Understanding the weather in Greenville is important when you plan your trip. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Greenville is 55 inches.
What's the best way to get to my boutique hotel in Greenville?
You have a few options for transportation to and around Greenville. The nearest major airport is Greenville-Spartanburg Intl. Airport (GSP), which is located 10.7 mi (17.2 km) from the heart of the city. If you want to explore the larger area, ride aboard one of the trains from Greenville Station.