Find Boutique Hotels in Jeffersonville, IN

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Jeffersonville Boutique Hotels

Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Jeffersonville boutique hotels

Free daily full breakfast
Market Street Inn

Market Street Inn

Market Street Inn
3.5 star property
Jeffersonville
9.8 out of 10, Exceptional, (120)
"I enjoyed my stay, however the breakfast portion was very small even for a petite person like myself, I was still very hungry after breakfast. There was a cleaning issue with the bathroom that was overlooked by the cleaning staff that I alerted the owners to that will hopefully be fixed for future visitors. The house is great and very clean overall. The owners are very nice."
United States
Megan
The price is AED 680
AED 769 total
includes taxes & fees
25 Dec - 26 Dec
Market Street Inn
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1000)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is AED 511
AED 619 total
includes taxes & fees
1 Jan - 2 January 2026
21c Museum Hotel Louisville
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1157)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Jeffersonville Hotel Reviews

The Brown Hotel

The Brown Hotel

10/10 Excellent
"Absolutely wonderful hotel! My room was large and the bathroom was huge! A walk in shower made it easier on my old knees. Service was A++++!! I can't wait to go back!!"
Abigail 1-night trip
Posted 7 hours ago
The Brown Hotel

Explore a world of travel with Expedia

Frequently asked questions

What's the best boutique-style accommodation in Jeffersonville?
Market Street Inn is a favorite B&B with our travelers looking for a stylish accommodation, and features 7 guestrooms, free breakfast, and free parking.
What's there to see and do in Jeffersonville?
The live music, riverfront, and restaurants are just some of the things to enjoy while you're in the area. Activities and attractions to experience around Jeffersonville include Charlestown State Park, Ohio River Valley, and Schimpffs Confectionery. Some other things you might want to enjoy include Howard Steamboat Museum, Derby Dinner Playhouse, and Thomas Edison House.
What kind of weather should I plan for when I travel to Jeffersonville?
Understanding the weather in Jeffersonville is important when you plan your trip. The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Jeffersonville is 56 inches.
What's the best way to get to my boutique hotel in Jeffersonville?
You have a few options for traveling to and around Jeffersonville. The nearest major airport is Louisville, KY (LOU-Bowman Field), which is located 5.8 mi (9.3 km) from the heart of the city, but Louisville Intl. Airport (SDF) may also be an option. If you'd like to explore around the area, you may want a rental car for your journey.