A sunny street lined with historic buildings, a 'ONE WAY' sign, and a flagpole with flags.

Find Resorts & Hotels with Spas in Key West, FL

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Check availability on Key West Resorts & Hotels with Spas

Our top choices for Key West hotels with a spa

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Old Town Key West
10.0 out of 10, Exceptional, (1,007 reviews)
"We really enjoyed our stay! The staff were amazing and the room was perfect!"
United States
Teresa
The price is AED 936
AED 1,052 total
includes taxes & fees
30 Nov - 1 Dec
Almond Tree Inn Hotel - Adults Only

2. Douglas House - Adults Only

Douglas House - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (588 reviews)
"Very good stay in Key west, good location and friendly staff, situated at the older town of key west, love the experience!"
Australia
Xiaojun
The price is AED 714
AED 1,030 total
includes taxes & fees
17 Nov - 18 Nov
Douglas House - Adults Only

3. The Gardens Hotel

The Gardens Hotel
4.0 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,001 reviews)
"Best place we have stayed. The staff was amazing location perfect and the room was perfect"
United States
Misty
The price is AED 905
AED 1,018 total
includes taxes & fees
30 Nov - 1 Dec
The Gardens Hotel

4. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,006 reviews)
"Fantastic property. Love staying here 💗"
United States
Jessica
The price is AED 1,025
AED 1,153 total
includes taxes & fees
15 Nov - 16 Nov
Orchid Key Inn - Adults Only

5. H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (674 reviews)
"Amazing stay! Loved the private pool!"
United States
Kimberly
The price is AED 1,319
AED 1,731 total
includes taxes & fees
30 Nov - 1 Dec
H2O Suites - Adults Only

6. Key West Villas

Key West Villas
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (279 reviews)
"Great location and very hospitable hotel owners"
United States
Margaret
The price is AED 988
AED 1,112 total
includes taxes & fees
18 Nov - 19 Nov
Key West Villas

7. Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Key West Historic District
9.8 out of 10, Exceptional, (1,000 reviews)
"Staff was great rooms are older but quite charming. Would definitely stay again."
United States
William
The price is AED 1,245
AED 1,401 total
includes taxes & fees
25 Nov - 26 Nov
Simonton Court Historic Inn & Cottages

8. Alexander's Guesthouse - Adult Exclusive

Alexander's Guesthouse - Adult Exclusive
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (176 reviews)
"We had such a great stay, nice property, Great location , the staff was helpful, friendly and fantastic! Delicious breakfast included … we really loved this place and we are looking forward to come back!"
United States
Nestor
The price is AED 757
AED 1,002 total
includes taxes & fees
12 Nov - 13 Nov
Alexander's Guesthouse - Adult Exclusive

9. The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (198 reviews)
"We really enjoyed getting to know the staff. The breakfast was excellent and everything was in walking distance."
United States
Jennifer
The price is AED 1,005
AED 1,131 total
includes taxes & fees
11 Nov - 12 Nov
The Conch House Heritage Inn

10. The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,002 reviews)
"This is my favorite hotel in the world, and Key West"
United States
Josh
The price is AED 1,495
AED 1,889 total
includes taxes & fees
29 Nov - 30 Nov
The Marquesa Hotel

11. Duval House

Duval House
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,138 reviews)
"Great stay!"
United States
Dennis
The price is AED 654
AED 814 total
includes taxes & fees
18 Nov - 19 Nov
Duval House

12. Island City House Hotel

Island City House Hotel
3.0 star property
Key West Historic District
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place with lots of character and perfect location."
United States
Elise
The price is AED 737
AED 829 total
includes taxes & fees
1 Dec - 2 Dec
Island City House Hotel

13. The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,001 reviews)
"Fun apartment style living in Key West…fun little patio with coffee and continental breakfast. Make sure you look at the check in hours :) great spot makes you feel local"
United States
Justyn
The price is AED 579
AED 743 total
includes taxes & fees
23 Nov - 24 Nov
The Grand Guesthouse

14. Santa Maria Suites

Santa Maria Suites
4.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,003 reviews)
"Great place for families"
United States
Anthony
The price is AED 1,322
AED 1,736 total
includes taxes & fees
2 Dec - 3 Dec
Santa Maria Suites

15. Tropical Inn

Tropical Inn
3.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (456 reviews)
"Staff are super friendly and went out of their way to accommodate us"
United States
Kelley
The price is AED 614
AED 783 total
includes taxes & fees
15 Nov - 16 Nov
Tropical Inn

16. The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (331 reviews)
"such a lovely location. nice and quiet for a restful stay. staff was attentive to all our needs. would definitely return"
United States
christine
The price is AED 1,162
AED 1,307 total
includes taxes & fees
29 Nov - 30 Nov
The Mermaid & Alligator

17. Westwinds Inn

Westwinds Inn
3.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,007 reviews)
"Breakfast was great . Pools were great and easy walk or bike ride to Duval street"
United States
Shari
The price is AED 793
AED 893 total
includes taxes & fees
29 Nov - 30 Nov
Westwinds Inn

18. L'Habitation Guest House - Adults Only

L'Habitation Guest House - Adults Only
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,003 reviews)
"A very cute, cozy and comfortable place to stay especially for old Key West charm. Will definitely stay here again."
United States
Callie
The price is AED 625
AED 703 total
includes taxes & fees
1 Dec - 2 Dec
L'Habitation Guest House - Adults Only

19. Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West
9.4 out of 10, Exceptional, (520 reviews)
"Clean room, comfortable bed, friendly staff, good amenities!"
United States
Lisa and David
The price is AED 808
AED 1,095 total
includes taxes & fees
30 Nov - 1 Dec
Ella's Cottages - Key West Historic Inns

20. Weatherstation Inn

Weatherstation Inn
2.5 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,003 reviews)
"This was the perfect location for access to Key West by foot!!!! We loved the community the resort is in!"
United States
Jane
The price is AED 804
AED 905 total
includes taxes & fees
11 Nov - 12 Nov
Weatherstation Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Key West

Spa hotels with pools in Key West

Spa hotels with free breakfast in Key West

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Key West Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Key West?
Forget the stress of everyday life and book yourself a lush spa hotel. Travelers love Key West for the sunsets and sea views so get ready to explore the great outdoors. Enjoy the live music and bars during your vacation. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key West?
Casa Marina Key West, Curio Collection by Hilton is a top spa hotel featuring a private beach, a fitness center, a bar, and a restaurant. Spend an afternoon at Spa Al Mare where you'll find facials, body scrubs, and deep-tissue massages and more. Other popular spa hotels in Key West include Southernmost Beach Resort and Guesthouses and Pier House Resort & Spa.
How many spa hotels will I find in Key West?
Among Expedia's 2618 accommodation options in Key West, there are 6 spa hotels.
What's there to see and do in Key West?
Take in the sights and attractions that Key West offers with a visit to Duval Street, Florida Keys Beaches, and Ernest Hemingway Home and Museum. If you have a bit of extra time while you're in the area, you might want to check out Key West Lighthouse and Keeper's Quarters Museum and Harry S. Truman Little White House.
What is a Key West spa hotel?
Spa hotels in Key West provide lodging and have an on-site spa which offers services such as couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.