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Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Our top choices for La Mesa vacation homes

A modern living room with a sofa, a chair, a coffee table, and a ceiling fan.

1. Entire Private Home w/ 4BR 3Bath, King Bed, Large Yard & Prime Area, Ranch Style

Entire Private Home w/ 4BR 3Bath, King Bed, Large Yard & Prime Area, Ranch Style
La Mesa
10.0 out of 10, Exceptional, (1 review)
"Great overall experience, clean room."
United States
Warren B.
Entire Private Home w/ 4BR 3Bath, King Bed, Large Yard & Prime Area, Ranch Style
A modern two-story house with a well-maintained lawn and a pathway leading to the front door.

2. Entire Private House with 4 Beds, Gated Yard, Parking, Ranch Style in La Mesa

Entire Private House with 4 Beds, Gated Yard, Parking, Ranch Style in La Mesa
La Mesa
Entire Private House with 4 Beds, Gated Yard, Parking, Ranch Style in La Mesa
A modern living room with a flat-screen TV, a sofa, and a dining area with a table set for four.

3. Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking

Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking
La Mesa
Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking
A modern kitchen with a large island, stainless steel appliances, and pendant lighting.

4. Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access

Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
La Mesa
9.0 out of 10, Wonderful, (10 reviews)
"We had a wonderful stay! The home is lovely, clean and exactly as described. Jonathan is very nice and easy to communicate with. We loved staying here to celebrate our son’s graduation from SDSU!"
United States
Anonymous traveler
Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
A living room with a sectional sofa, a red armchair, a wooden coffee table, and a ceiling fan.

5. Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!

Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!
Spring Valley
9.2 out of 10, Wonderful, (9 reviews)
"Location was perfect for our needs. Great space for the dogs too. "
United States
Hayley G.
Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!
A living room with a flat-screen TV, a sofa, a dining area with a table and chairs, and a kitchen area with a fridge and a microwave.

6. Hermosa Casa en Spring Valley

Hermosa Casa en Spring Valley
Spring Valley
8.4 out of 10, Very good, (17 reviews)
"Great value and good location. Comfortable stay for the 4 of us."
United States
Pierre B.
Hermosa Casa en Spring Valley
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table with upholstered chairs.

7. La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.2 out of 10, Wonderful, (13 reviews)
"Owner was gracious to let us stay 2 extra hours"
United States
Janet
La Mesa Family Retreat - 20 minutes to Beaches & More!
A gravel pathway with red bricks leading to a gate.

8. La Casita Guest House, private fenced yard & with heat and AC, pet friendly

La Casita Guest House, private fenced yard & with heat and AC, pet friendly
Mount Helix
9.8 out of 10, Exceptional, (15 reviews)
"Thank you so much for the hospitality and your kindness"
United States
Lisa D.
La Casita Guest House, private fenced yard & with heat and AC, pet friendly
A living room with a beige sofa, two armchairs, a coffee table, and a rug. There are two lamps, a painting on the wall, and a window with a view of greenery and a blue car outside.

9. 'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
Encanto
8.8 out of 10, Excellent, (43 reviews)
"Beds were very comfortable."
United States
Paula
The price is AED 301
AED 915 total
includes taxes & fees
8 Nov - 9 Nov
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
A living room with a flat-screen TV on a wooden wall, a sofa, a coffee table with a tray, and a door leading to another room.

10. SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.

SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.
Mid-City
9.4 out of 10, Exceptional, (19 reviews)
"The location was great for getting to all the top attractions in San Diego. The back yard and garden was very peaceful and great for kids to explore!"
United States
Jenna T.
SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.
A deck with two wicker chairs and a small table, overlooking a mountainous landscape and a body of water.

11. Luxury Studio with Lake Views and Spacious Balcony

Luxury Studio with Lake Views and Spacious Balcony
Spring Valley
8.0 out of 10, Very good, (8 reviews)
"Great place"
United States
Brian
Luxury Studio with Lake Views and Spacious Balcony
A modern living room with a grey sofa, a small round coffee table, and a ceiling fan.

12. Charming 1-bedroom house in Beautiful San Diego with WiFi, AC

Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
Mid-City
10.0 out of 10, Exceptional, (2 reviews)
"Our stay was excellent. We enjoyed the space. Used TV, sofa and bed… nothing else. Quiet and easy access to property. "
United States
Socorro C.
The price is AED 514
AED 1,108 total
includes taxes & fees
2 Nov - 3 Nov
Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
A modern kitchen with a gas stove, a microwave, and a dishwasher. There is a wooden cutting board with utensils on it, and a potted plant on the counter.

13. Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (112 reviews)
"Easy to get to location in a good neighborhood! Nice and clean quiet despite being close to everything!"
United States
Anonymous traveler
The price is AED 918
AED 1,164 total
includes taxes & fees
1 Nov - 2 Nov
Beautiful Normal Heights Living
A modern kitchen with a central island, wooden bar stools, and a dining area set for six.

14. 3-bedroom house in lovely San Diego with garage. Enjoy your stay

3-bedroom house in lovely San Diego with garage. Enjoy your stay
El Cajon
9.6 out of 10, Exceptional, (4 reviews)
"Clean rooms, everything was accurate as it was described in the description. "
United States
Virgilio Alan A.
3-bedroom house in lovely San Diego with garage. Enjoy your stay
A modern living room with a sofa, coffee table, and a dining area with chairs and a table.

15. Modern Hideaway in North Park - 3941

Modern Hideaway in North Park - 3941
North Park
10.0 out of 10, Exceptional, (3 reviews)
"Such a great experience here! The host was very communicative and attentive. Spot was clean and perfect for our weekend getaway. There are plenty of bars and cool shops within walking distance. We will definitely be booking the same spot on our next trip!"
United States
Madison S.
The price is AED 298
AED 904 total
includes taxes & fees
16 Nov - 17 Nov
Modern Hideaway in North Park - 3941
A modern kitchen with wooden cabinets, stainless steel appliances, and a dining area with a table and chairs.

16. Spacious 4BR - Fletcher Hills Retreat

Spacious 4BR - Fletcher Hills Retreat
Fletcher Hills
10.0 out of 10, Exceptional, (1 review)
"There were plenty of rooms for everyone which was amazing to come with a large group. We used it as a 5 bedroom. The 2 bathrooms are great too. There could have been more seating in the living room and maybe small lamps in the bedrooms. The hosts were helpful and they respond quickly. The neighborhood is safe and close to many convenient places like grocery store, dollar tree, CVS. There is also a lot of options for food close by. Highway is close and the house location was only 20 minutes...
United States
Sofia K.
Spacious 4BR - Fletcher Hills Retreat
A modern living room with a sectional sofa, a dining area with a white table and chairs, a kitchen with white cabinets and stainless steel appliances, and a large painting on the wall.

17. Gillespie 1059 unit C 3bed 2 bath by SD Stay

Gillespie 1059 unit C 3bed 2 bath by SD Stay
Spring Valley
8.6 out of 10, Excellent, (8 reviews)
"Wonderful stay, as advertised - thank you!"
United States
Stacey L.
Gillespie 1059 unit C 3bed 2 bath by SD Stay
A modern hotel room with a large bed, a TV, a desk, and a bathroom visible through an open door.

18. Family Haven: Sports Court, Game Room, King Beds

Family Haven: Sports Court, Game Room, King Beds
Fletcher Hills
10.0 out of 10, Exceptional, (6 reviews)
"Wonderful stay - kids had an amazing time in the game room/garage."
United States
Calvin C.
Family Haven: Sports Court, Game Room, King Beds
A modern kitchen with a wooden dining table, black chairs, and a view of the outdoors.

19. 3bed/2ba, Fam Friendly, Views & Downtown

3bed/2ba, Fam Friendly, Views & Downtown
Encanto
9.0 out of 10, Wonderful, (6 reviews)
"We enjoyed our experience and grateful for this time here. "
United States
Lowlan B.
3bed/2ba, Fam Friendly, Views & Downtown
A modern kitchen with white cabinets, a stainless steel dishwasher, a stove, and a refrigerator.

20. Cozy Private Home, 10-min From DT, Beach & Parks

Cozy Private Home, 10-min From DT, Beach & Parks
Mid-City
8.2 out of 10, Very good, (20 reviews)
"Awesome stay, Nothing but great things to say! "
United States
Brayden C.
The price is AED 489
AED 1,037 total
includes taxes & fees
1 Nov - 2 Nov
Cozy Private Home, 10-min From DT, Beach & Parks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent
"Nothing to add."
Lea 1-night trip
Posted 1 hour ago
Days Inn by Wyndham San Diego Hotel Circle

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