A marshy landscape with water, trees, and a distant city skyline.

Find Resorts & Hotels with Spas in Ladys Island, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Ladys Island Resorts & Hotels with Spas

Tonight
2 Oct - 3 Oct
Tomorrow
3 Oct - 4 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Ladys Island hotels with a spa

A two-story white colonial-style building with a central entrance, columns, and a balcony on the upper floor.
A spacious bathroom with a large bathtub, wooden paneling, and a glass table with a chair.
A traditional living room with a fireplace, two sofas, a coffee table, and a bookshelf.
A bathroom with a white vanity, a large mirror, and a hanging light fixture.

1. Anchorage 1770

Anchorage 1770
Historic District
  • Luxuriate in historic charm with rooftop terrace views and rejuvenating spa massages at this beautifully maintained hotel.
AED 967
AED 1,064 total
includes taxes & fees
4 Oct - 5 Oct
Anchorage 1770
A person lying in a bathtub with multiple showerheads, a tiled wall, and a mosaic tile pattern in the background.
A balcony with a view of a beach and a pool area.
A hotel with multiple floors, a swimming pool, and a beach area.
An outdoor dining area with tables set for a meal, surrounded by trees and overlooking a body of water.

2. Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island
Mid Island
  • Discover tranquil oceanside renewal with spa treatments, pools, and garden serenity at this waterfront island resort.
AED 629
AED 846 total
includes taxes & fees
30 Oct - 31 Oct
Hilton Beachfront Resort & Spa Hilton Head Island
A reception area with a stone wall, wooden reception desk, and wicker chairs.
A large resort with multiple buildings, a swimming pool, and a beach area.
A spacious dining area with wooden flooring, a long table set for a meal, and large windows offering a view of the outdoors.
A resort pool area with a view of the ocean at sunset, surrounded by palm trees and string lights.

3. The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa
Mid Island
  • Rejuvenate at this beachfront retreat featuring a 9-room heavenly spa, three outdoor pools, and sun-soaked balconies for a blissful escape.
AED 658
AED 899 total
includes taxes & fees
11 Oct - 12 Oct
The Westin Hilton Head Island Resort & Spa
A room with three armchairs, each with a small table and a lamp. The walls have a leaf-pattern wallpaper.
A balcony with wicker furniture overlooking a pool and beach.
A resort with multiple swimming pools, sun loungers, and a view of the ocean.
An outdoor dining area with a view of the beach, string lights, and palm trees.

4. Omni Hilton Head Oceanfront Resort

Omni Hilton Head Oceanfront Resort
Mid Island
  • Unwind in coastal luxury at this full-service spa retreat offering couples treatments, beach yoga, and three pristine outdoor pools.
AED 777
AED 1,048 total
includes taxes & fees
1 Nov - 2 Nov
Omni Hilton Head Oceanfront Resort
A modern hotel corridor with a wooden reception desk, a bench, and shelves displaying toiletries.
An aerial view of a resort with a central swimming pool, multiple buildings, and lush greenery.
A wooden boardwalk leading to a beach with a view of the ocean.
A resort with a large pool, palm trees, and a view of the ocean.

5. Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island
South End
  • Serene beachfront spa retreat offers Ayurvedic treatments and aromatherapy for total renewal.
AED 613
AED 848 total
includes taxes & fees
1 Nov - 2 Nov
Sonesta Resort Hilton Head Island
A reception area with a wooden reception desk, a flat-screen TV, and a wall-mounted sign that reads "namaste spa".
A beach with waves at sunset.
An aerial view of a coastal resort with beachfront properties, a swimming pool, and lush greenery.
An indoor swimming pool with clear glass ceilings, multiple lounge chairs, and a view of the outdoors.

6. Marriott's Barony Beach Club

Marriott's Barony Beach Club
Mid Island
  • Rejuvenate at this beachfront condo resort with a full-service Namaste Spa offering Ayurvedic treatments, body wraps, and various massages.
AED 1,264
AED 1,390 total
includes taxes & fees
1 Nov - 2 Nov
Marriott's Barony Beach Club
Two people in separate bathtubs in a room with wooden flooring, a small table with a bottle, and a framed artwork on the wall.
A large house with a covered porch, a chimney, and a driveway.
A covered outdoor seating area with wicker furniture and large windows overlooking a garden.
A view through large windows of a landscaped garden with a circular stone feature, surrounded by potted plants.

7. Montage Palmetto Bluff

Montage Palmetto Bluff
Palmetto Bluff
  • Riverside serenity awaits at this hotel's award-winning spa with massage rooms and hydrotherapy treatments for relaxation.
AED 2,736
AED 3,265 total
includes taxes & fees
11 Oct - 12 Oct
Montage Palmetto Bluff
A room with two beds, a ceiling fan, and large windows with a view of the beach.
A spacious living area with a sofa, chairs, and a TV.
A pool with lounge chairs and palm trees, surrounded by a landscaped area with a view of the ocean.
An aerial view of a resort with multiple buildings, a central swimming pool, and a beach in the background.

8. Marriott's Grande Ocean

Marriott's Grande Ocean
South End
  • Oceanfront retreat with full-service spa offers rejuvenating escapes, featuring 5 hot tubs and a serene garden for complete relaxation.
AED 1,120
AED 1,232 total
includes taxes & fees
20 Oct - 21 Oct
Marriott's Grande Ocean
A historic building with a covered porch and a brick pathway.
A modern bedroom with a four-poster bed, a large window with a view of trees, and a unique ceiling light fixture.
A spacious patio with a dining area, wicker furniture, and a view of trees.
A modern kitchen with white cabinetry, a central island with a bowl, two wicker chairs, a hanging light fixture, a stove, and a view of greenery through large windows.

9. Montage Palmetto Bluff Residences

Montage Palmetto Bluff Residences
Palmetto Bluff
  • Riverside luxury spa escape with 13 treatment rooms, deep soaking tubs, and hot stone massages awaits at Montage.
AED 4,951
AED 5,950 total
includes taxes & fees
1 Nov - 2 Nov
Montage Palmetto Bluff Residences
View all properties

Choose what matters most at spa hotels in Ladys Island

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Ladys Island Hotel Reviews

Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island

8/10 Good
"The location"
frank 1-night trip
Posted 6 hours ago
Hilton Beachfront Resort & Spa Hilton Head Island
The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa

8/10 Good
"I general we enjoyed our stay. Given the prices at the Westin I expect better toilet paper. The comforters were way too heavy for a warm climate."
Lyn 4-night trip
Posted 1 day ago
The Westin Hilton Head Island Resort & Spa
Palmera Inn and Suites

Palmera Inn and Suites

8/10 Good
"The hotel is in a good location. The room was updated and clean. Unfortunately the doors and walls are razor thin and you hear every conversation and every person walking through the gallery. Also, they had a DJ playing electric music after 11 that pulsated the room."
Kelly 2-night trip
Posted 2 days ago
Palmera Inn and Suites
Beaufort Inn

Beaufort Inn

8/10 Good
"Was very nice and clean."
Alicia Ann 1-night trip
Posted 4 days ago
Beaufort Inn

Explore a world of travel with Expedia